419 research outputs found

    Psychological symptoms in obesity and related factors

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    Introduction: This study aimed to investigate the relationship between levels of depression and anxiety symptoms and quality of life, self-esteem in obesity. Methods: Fifty-two subjects whose Body Mass Index (BMI) is 30 kg/m² and over and 43 control whose BMI is normal were recruited for this study. The socio demographic data form, Hamilton Depression Rating Scale (HAM-D17), Hamilton Anxiety Rating Scale (HAM-A), Quality of Life Scale Short Form (WHOQOL-Brief-TR), Coopersmith Self Esteem Scale (CSES), The Eating Attitudes (EAT), were applied to the participants. Results: In this study most of the patients are women, married, postgraduated and live in urban areas. It was determined to scores of HAM-D17, HAM-A and EAT are higher in obese group than control group; WHOQOL-Brief-TR physical field scores was lower in obese group than control group. CSES scores wasn’t difference between obese and control group. In obese group, there was HAM-D17 and HAM-A scores a negative correlation between quality of life physical field score, negative correlation between CSES score, positive correlation between EAT scale score. There is no correlation between scores of HAM-D17 and HAM-A and BMI. Conclusion: Our results suggest that depressive and anxiety levels are high in induvidual with obesity. They have problems in eating attitudes and their quality of life especially physical field is poor. The psychological symptoms have negative effects on the quality of life, self-esteem, and eating attitudes. Our results suggest that psychiatric support to improving positive effects quality of life and self-esteem in individual with obesity. © 2015 by Turkish Association of Neuropsychiatry

    Testing justification for segment based relevant product market definition in merger control: Evidence from Turkey

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    In this paper, we aim to investigate whether different segments of beer products can constitute a separate relevant product market within the framework of competition law. This question gained importance when the merger between Anheuser-Busch InBev and SABMiller became subject to a Phase II investigation by the Turkish Competition Authority in March 2016, which ultimately ended with an unconditional clearance decision, based on an intact "beer" market, recognizing that the relevant product market regarding beer brands in Turkey must be wider than the premium segment. To answer the research question above concerning relevant product market definition, we implement a Hypothetical Monopolist Test in two steps. In the first step, the aggregate price elasticity of demand for the premium segment is estimated econometrically by using a nested logit demand model. This model tests whether products in the same group are closer substitutes than products in different groups. We conclude that the correlation of beers within the same group is not statistically significant. Since the data in our study are obtained at the retail level, the price elasticity of demand at the brewer level is derived from the estimate at the retailer level by using very conservative assumptions with regard to the passthrough rates. In the second step, the hypothetical monopolist test is implemented by using the critical elasticity which is calculated by using the profit margins for the premium beer segment at brewer/supplier level under both 5 percent and 10 percent SSNIP. It is seen that the actual elasticity of demand for the premium segment is larger than the critical elasticity (in absolute value) under both scenarios. These findings show that the relevant product market regarding beer brands in Turkey must be wider than the premium segment. © The Author 2017. Published by Oxford University Press. All rights reserved

    Defined conditions for propagation and manipulation of mouse embryonic stem cells.

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    The power of mouse embryonic stem (ES) cells to colonise the developing embryo has revolutionised mammalian developmental genetics and stem cell research. This power is vulnerable, however, to the cell culture environment, deficiencies in which can lead to cellular heterogeneity, adaptive phenotypes, epigenetic aberrations and genetic abnormalities. Here, we provide detailed methodologies for derivation, propagation, genetic modification and primary differentiation of ES cells in 2i or 2i+LIF media without serum or undefined serum substitutes. Implemented diligently, these procedures minimise variability and deviation, thereby improving the efficiency, reproducibility and biological validity of ES cell experimentation.The funding statement is uploaded separately from the manuscript but the authors acknowledged Wellcome Trust, BBSRC and MRC. Austin Smith is an MRC Professor

    Quantification of Thermal Oxidation in Metallic Glass Powder using Ultra-small Angle X-ray Scattering

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    In this paper, the composition, structure, morphology and kinetics of evolution during isothermal oxidation of Fe 48Cr 15Mo 14Y 2C 15B 6 metallic glass powder in the supercooled region are investigated by an integrated ex-situ and in-situ characterization and modelling approach. Raman and X-ray diffraction spectra established that oxidation yielded a hierarchical structure across decreasing length scales. At larger scale, Fe 2O 3 grows as a uniform shell over the powder core. This shell, at smaller scale, consists of multiple grains. Ultra-small angle X-ray scattering intensity acquired during isothermal oxidation of the powder over a wide Q-range delineated direct quantification of oxidation behavior. The hierarchical structure was employed to construct a scattering model that was fitted to the measured intensity distributions to estimate the thickness of the oxide shell. The relative gain in mass during oxidation, computed theoretically from this model, relatively underestimated that measured in practice by a thermogravimetric analyzer due to the distribution in sizes of the particles. As a whole, this paper introduces the first direct quantification of oxidation in metallic glass powder by ultra-small angle X-ray scattering. It establishes novel experimental environments that can potentially unfold new paradigms of research into a wide spectrum of interfacial reactions in powder materials at elevated temperatures

    Recorded Motions of the Mw6.3 April 6, 2009 L’Aquila (Italy) Earthquake and Implications for Building Structural Damage: Overview.

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    The normal-faulting earthquake of 6 April 2009 in the Abruzzo Region of central Italy caused heavy losses of life and substantial damage to centuriesold buildings of significant cultural importance and to modern reinforcedconcrete- framed buildings with hollow masonry infill walls. Although structural deficiencies were significant and widespread, the study of the characteristics of strong motion data from the heavily affected area indicated that the short duration of strong shaking may have spared many more damaged buildings from collapsing. It is recognized that, with this caveat of shortduration shaking, the infill walls may have played a very important role in preventing further deterioration or collapse of many buildings. It is concluded that better new or retrofit construction practices that include reinforcedconcrete shear walls may prove helpful in reducing risks in such seismic areas of Italy, other Mediterranean countries, and even in United States, where there are large inventories of deficient structures.Published651-6844.1. Metodologie sismologiche per l'ingegneria sismicaJCR Journalreserve

    Hybrid EEFIT mission to february 2023 Kahramanmaraş earthquake sequence

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    The southwestern part of Türkiye was hit on 6 February 2023 by an Mw 7.8 (epicentre:Pazarcık) and then an Mw 7.5 earthquake (epicentre: Elbistan). The event was followed by tensof thousands of aftershocks including the Mw 6.3 event on 20 February (epicentre: Uzunbağ).This paper reports on the preliminary findings of the mission organised by the UK’s EarthquakeEngineering Field Investigation Team (EEFIT) to the Kahramanmaraş Earthquake sequence ofFebruary 2023. This mission followed a hybrid model, combining field and remote investigationtechniques, to investigate the characteristics of the earthquake sequence, its impact on buildingsand infrastructure, as well as the efficacy of relief, response and recovery operations. The keymessages include that the building stock is hard to categorise which brings along difficulties withdamage assessment, that the recovery and reconstruction require multi-sectoral engagement ofkey stakeholders, and that the auditing and quality control mechanisms within the constructionindustry need revisiting in the way forward for better disaster resilience in Türkiye

    Shaking table tests and numerical analyses on a scaled dry-joint arch undergoing windowed sine pulses

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    The damages occurred during recent seismic events have emphasised the vulnerability of vaulted masonry structures, one of the most representative elements of worldwide cultural heritage. Although a certain consensus has been reached regarding the static behaviour of masonry arches, still more efforts are requested to investigate their dynamic behaviour. In this regard, the present paper aims to investigate the performance of a scaled dry-joint arch undergoing windowed sine pulses. A feature tracking based measuring technique was employed to evaluate the displacement of selected points, shading light on the failure mechanisms and gathering data for the calibration of the numerical model. This was built according to a micro-modelling approach of the finite element method, with voussoirs assumed very stiff and friction interface elements. Comparisons with existing literature are also stressed, together with comments about scale effects.This work was partly financed by FEDER funds through the Competitivity Factors Operational Programme-COMPETE and by national funds through FCT-Foundation for Science and Technology within the scope of the Project POCI-01-0145-FEDER-007633.info:eu-repo/semantics/publishedVersio

    The Türki̇ye earthquake sequence of February 2023: A longitudinal study report by EEFIT

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    On 6 February 2023 at 4:17 am local time, a large area in southeastern Türkiye and northern Syria was hit by an Mw 7.8 earthquake, which was followed by an Mw 7.5 earthquake at 1:24 pm local time, causing the loss of more than 50,000 lives, some 100,000 injuries and significant damage to buildings and infrastructure, estimated to be in the range of 84.1 billion USD for Türkiye alone. The largest earthquake in Türkiye since the deadly 1939 Erzincan earthquake with however much larger losses, the sequence immediately attracted the attention of the global post-disaster reconnaissance/engineering communities. This included the Earthquake Engineering Field Investigation Team (EEFIT), who, within one week of the event, gathered a team with 30 people from academia and industry in the UK (19), Türkiye (5), New Zealand (1), Hungary (1), Bulgaria (1), Greece (1) and USA (1) with two support members from the UK and the Netherlands, to study the events and their impacts, and also to develop suggestions to reduce the existing vulnerabilities in the future. The team was organised in the form of 6 working groups as shown below, which were (1) strong ground motions and seismotectonics, (2) geotechnics, (3) structures, (4) infrastructure, (5) remote sensing and (6) relief response and recovery
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