Is economic planning hypercomputational? The argument from Cantor diagonalisation

Murphy [26] argues that the diagonal argument of the number theorist Cantor can be used to elucidate issues that arose in the socialist calculation debate of the 1930s. In particular he contends that the diagonal argument buttresses the claims of the Austrian economists regarding the impossibility of rational planning.We challenge Murphy’s argument, both at the number theoretic level and from the standpoint of economic realism

Mineral Losses in Gases and Fumes.

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PTRE-seq reveals mechanism and interactions of RNA binding proteins and miRNAs

A large number of RNA binding proteins (RBPs) and miRNAs bind to the 3′ untranslated regions of mRNA, but methods to dissect their function and interactions are lacking. Here the authors introduce post-transcriptional regulatory element sequencing (PTRE-seq) to dissect sequence preferences, interactions and consequences of RBP and miRNA binding

Globular Cluster Formation in M82

We present high resolution mid-infrared (mid-IR; 11.7 and 17.65 micron) maps of the central 400 pc region of the starburst galaxy M82. Seven star forming clusters are identified which together provide ~ 15% of the total mid-IR luminosity of the galaxy. Combining the mid-IR data with thermal radio measurements and near- and mid-IR line emission, we find that these young stellar clusters have inferred masses and sizes comparable to globular clusters. At least 20% of the star formation in M82 is found to occur in super-star clusters.Comment: 12 pages including three color figures; accepted for publication in Ap

Electrical Precipitation

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A Comparison of the Effects of Static Stretching Alone to Static Stretching Plus Slow Deep Breathing on Hip Flexion Range of Motion

Restricted hip range of motion (ROM) is a common issue for both the general public due to muscle tightness associated with an increased sedentary lifestyle and individuals with diaphragmatic breathing dysfunction. There is evidence that both static stretching treatment and proper breathing mechanics, increase hip ROM, however, it is unclear whether ROM can be enhanced by combining these techniques. The purpose of this study is to compare the effects of static stretching (SS) to static stretching combined with slow deep breathing (SS+SDB) on hamstring flexibility as measured by hip flexion. Eleven healthy participants between the ages of 18-30 with no current musculoskeletal injury, or diagnosed respiratory disease, reported for two separate test days, 1 to 4 weeks apart. The SS intervention consisted of a standing one-legged hamstring stretch for 2 sets of 30 seconds bilaterally with 10 seconds rest between sets. The SS+SDB intervention consisted of the same stretching protocol as used in the SS intervention with the addition of slow deep diaphragmatic breathing at a rate of 4 seconds inhale, 2 seconds hold, 4 seconds exhale. The order of the interventions was randomly assigned. Pre-and post-intervention measurements of hip flexion were acquired through completing an active straight leg raise bilaterally with video analysis. Post-intervention left and right hip flexion was normalized to pre-intervention hip flexion, averaged by intervention, and then compared using a T-test. There was a significant increase in hip flexion for the SS+SDB when compared to SS for both the right leg (3.91% +/- 1.57 vs 9.17% +/- 1.77, p \u3c 0.05), and left leg (2.88% +/- 1.03 vs 9.27% +/- 1.74, p \u3c 0.05). A separate analysis was conducted comparing the different treatment effects by gender which revealed no significant differences. In conclusion, this data suggests that the addition of slow deep breathing to static stretching produces a greater increase in hip ROM when compared to static stretching alone. Therefore, when aiming to increase hip ROM through static stretching it is important to incorporate slow deep breathing

Functional consequences of heterogeneous gap junction channel formation and its influence in health and disease

AbstractThe capacity of multiple connexins to hetero-oligomerize into functional heterogeneous gap junction channels has been demonstrated in vivo11Used herein to denote in an animal., in vitro22Used herein to denote in cultured cells., and in nonmammalian expression systems. These heterogeneous channels display gating activity, channel conductances, selectivity and regulatory behaviors that are sometimes not predicted by the behaviors of the corresponding homogeneous channels. Such observations suggest that heteromerization of gap junction proteins offers an efficient cellular strategy for finely regulating cell-to-cell communication. The available evidence strongly indicates that heterogeneous gap junction assembly is important to normal growth and differentiation, and may influence the appearance of several disease states. Definitive evidence that heterogeneous gap junction channels differentially regulate electrical conduction in excitable cells is absent. This review examines the prevalence, regulation, and implications of gap junction channel hetero-oligomerization

Wellbeing in long-term primary carers: biopsychosocial outcomes

Carers are vital to sustaining the independence and optimal functioning of some of the most vulnerable members of the community, yet carers themselves are at risk of poor health and wellbeing outcomes. Indeed, carers often subjugate their own needs in order to fulfill their caring role. This study examined wellbeing outcomes in long-term primary carers. The consequences of providing extended informal care were investigated using a mixed methodology, including questionnaires, saliva sampling and individual interviews. Carers and age and gender matched non-carers were compared across stress, distress, and subjective wellbeing as well as sleep variables and stress hormones. The findings are used to explore the biopsychosocial bases of carer wellbeing. This research has the potential to inform policy on the growing population of Australian carers and to add to the developing wellbeing literature

AGB subpopulations in the nearby globular cluster NGC 6397

It has been well established that Galactic Globular clusters (GCs) harbour more than one stellar population, distinguishable by the anti-correlations of light element abundances (C-N, Na-O, and Mg-Al). These studies have been extended recently to the asymptotic giant branch (AGB). Here we investigate the AGB of NGC 6397 for the first time. We have performed an abundance analysis of high-resolution spectra of 47 RGB and 8 AGB stars, deriving Fe, Na, O, Mg and Al abundances. We find that NGC 6397 shows no evidence of a deficit in Na-rich AGB stars, as reported for some other GCs - the subpopulation ratios of the AGB and RGB in NGC 6397 are identical, within uncertainties. This agrees with expectations from stellar theory. This GC acts as a control for our earlier work on the AGB of M 4 (with contrasting results), since the same tools and methods were used.Comment: 10 pages, 7 figures, 8 tables (2 online-only). Accepted for publication in MNRA