Dark matter search results from the complete exposure of the PICO-60 C3F8 bubble chamber

[EN] Final results are reported from operation of the PICO-60 C3F8 dark matter detector, a bubble chamber filled with 52 kg of C3F8 located in the SNOLAB underground laboratory. The chamber was operated at thermodynamic thresholds as low as 1.2 keV without loss of stability. A new blind 1404-kg-day exposure at 2.45 keV threshold was acquired with approximately the same expected total background rate as the previous 1167-kg-day exposure at 3.3 keV. This increased exposure is enabled in part by a new optical tracking analysis to better identify events near detector walls, permitting a larger fiducial volume. These results set the most stringent direct-detection constraint to date on the weakly interacting massive particle (WIMP)-proton spin-dependent cross section at 3.2 x 10(-41) cm(2) for a 25 GeV WIMP, improving on previous PICO results for 3-5 GeV WIMPs by an order of magnitude.The PICO Collaboration wishes to thank SNOLAB and its staff for support through underground space, logistical and technical services. SNOLAB operations are supported by the Canada Foundation for Innovation and the Province of Ontario Ministry of Research and Innovation, with underground access provided by Vale at the Creighton mine site. We are grateful to Genevieve Belanger and Alexander Pukhov of the Universit e de Savoie for their useful correspondence regarding the interpretation of PICO results. We wish to acknowledge the support of the Natural Sciences and Engineering Research Council of Canada (NSERC) and the Canada Foundation for Innovation (CFI) for funding. We acknowledge the support from the National Science Foundation (NSF) (Grants No. 0919526, No. 1506337, No. 1242637, No. 1205987, and No. 1806722). We acknowledge that this work is supported by the U.S. Department of Energy (DOE) Office of Science, Office of High Energy Physics (under Award No. DE-SC-0012161), by the DOE Office of Science Graduate Student Research (SCGSR) award, by DGAPA-UNAM (PAPIIT No. IA100118) and Consejo Nacional de Ciencia y Tecnologia (CONACyT, Mexico, Grants No. 252167 and No. A1-S-8960), by the Department of Atomic Energy (DAE), Government of India, under the Centre for AstroParticle Physics II project (CAPP-II) at the Saha Institute of Nuclear Physics (SINP), European Regional Development FundProject "Engineering applications of microworld physics" (No. CZ. 02.1.01/0.0/0.0/16_019/0000766), and the Spanish (Ministry of Science, Innovation and Universities) Ministerio de Ciencia, Innovacion y Universidades (Red Consolider MultiDark, FPA2017-90566-REDC). This work is partially supported by the Kavli Institute for Cosmological Physics at the University of Chicago through NSF Grant No. 1125897, and an endowment from the Kavli Foundation and its founder Fred Kavli. We also wish to acknowledge the support from Fermi National Accelerator Laboratory under Contract No. DE-AC02-07CH11359, and from Pacific Northwest National Laboratory, which is operated by Battelle for the U.S. Department of Energy under Contract No. DE-AC05-76RL01830. We also thank Compute Canada (www.computecanada.ca) and the Centre for Advanced Computing, ACENET, Calcul Quebec, Compute Ontario and WestGrid for computational support.Amole, C.; Ardid Ramírez, M.; Arnquist, I.; Asner, DM.; Baxter, D.; Behnke, E.; Bressler, M.... (2019). Dark matter search results from the complete exposure of the PICO-60 C3F8 bubble chamber. Physical Review D: covering particles, fields, gravitation, and cosmology. 100(2):1-9. https://doi.org/10.1103/PhysRevD.100.022001191002Olive, K. A. 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