1,085 research outputs found

    Finding RR Lyrae Stars with SkyMapper: an Observational Test

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    One of the major science goals of the SkyMapper Survey of the Southern Hemisphere sky is the determination of the shape and extent of the halo of the Galaxy. In this paper we quantify the likely efficiency and completeness of the survey as regards the detection of RR Lyrae variable stars, which are excellent tracers of the halo stellar population. We have accomplished this via observations of the RR Lyrae-rich globular cluster NGC 3201. We find that for single epoch uvgri observations followed by two further epochs of g, r imaging, as per the intended three-epoch survey strategy, we recover known RR Lyraes with a completeness exceeding 90%. We also investigate boundaries in the gravity-sensitive single-epoch two-color diagram that yield high completeness and high efficiency (i.e., minimal contamination by non-RR Lyraes) and the general usefulness of this diagram in separating populations.Comment: 10 pages, 5 figures, to appear in the Publications of the Astronomical Society of Australia (PASA), published by Cambridge University Pres

    Exploring the perceptions of Patients with Chronic Respiratory Diseases and their insights into Pulmonary Rehabilitation in Bangladesh

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    Background: Chronic respiratory diseases (CRDs) require holistic management reflecting patient preferences, appropriate pharmacotherapy, pulmonary rehabilitation, and integrated care. We aimed to understand the perceptions of people with CRDs about their condition and pulmonary rehabilitation in Bangladesh.Methods: We conducted semi-structured interviews with a maximum variation sample of people with CRD who had participated in a feasibility study of pulmonary rehabilitation in 2021/ 2022. Interviews were transcribed verbatim, analysed in Bengali using a grounded theory approach and interpreted by a multidisciplinary team.Results: We interviewed 15 participants with COPD, asthma, or post-tuberculosis. Analysis revealed three themes. 1) Understanding CRD: patients characterised their condition by the symptoms (e.g., ‘Hapani’ meaning ‘breathlessness’) rather than describing a disease entity. Some identified occupation, previous infection or family history that they believed was the cause. 2) Perceptions of pulmonary rehabilitation: Exercise was counterintuitive as it exacerbated the breathlessness symptom that defined their disease. Views varied, though many acknowledged the benefits after a few sessions. Even with home-based programmes, participants described practical barriers to finding time for the sessions and adopted strategies to overcome the challenges. 3) Implementation: Participants highlighted the need for raising awareness of CRD and the potential of pulmonary rehabilitation in the community, adapting to the local context, and establishing an accessible resourced service. Conclusion: Understanding how patients and their communities perceive their condition and the barriers (both conceptual and logistical) to acceptance is the first step to embedding this highly effective intervention into routine healthcare services in Bangladesh with potential benefits for the increasing number of people living with CRDs in LMICs.<br/

    Nanomedicines as cancer therapeutics: Current status

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    As of 21st century, cancer is arguably the most complex and challenging disease known to mankind and an inevitable public health concern of this millennium. Nanotechnology, suitably amalgamated with cancer research, has ushered an era of highly personalized and safer medicines which can improve cancer diagnosis and therapy. A wide variety of nanomedicines are currently under investigation, including polymeric/non-polymeric nanoparticles, dendrimers, quantum dots, carbon nanotubes, lipid- and micelle-based nanoparticles. The bases of these nanomedicines in reducing toxicity associated with cancer therapy are their ability to carry a large payload and multivalent-ligand targeting. This imparts specificity for targeting the tissues as well as bypass resistance mechanisms. The major hurdles on these future medicines are potential toxicity of nanoparticles, which imposes the need of extensive regulatory evaluation before nanomedicines could be utilized as cancer therapeutics. This review highlights nanopharmaceuticals that have been investigated in oncology for various applications (diagnosis, therapeutic delivery and theranostics). It also discusses the effects of nano-sized materials on tissues/organ functions, the possibility of overcoming multi-drug resistance by using nanomedicines and their current clinical status

    Microstructure and Magnetic Properties of Very Thin CoCr Films Deposited on Different Underlayers by rf-Sputtering

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    Very thin CoCr films deposited on different underlayers on glass disk substrates were studied by the magneto-optic Kerr effect, VSM, torque magnetometry and TEM selected area diffraction. Square or near square perpendicular loops were obtained from Co/Ti, CoCr/Au, CoCr/Al, CoCr/C and CoCr/Si films. TEM SAD study revealed that the crystalline structure is a key factor determining the magnetic anisotropy of the very thin CoCr films. In particular, the c-axis of the hep CoCr films which exhibit square perpendicular loops is perpendicular to the film plane whilst that of the CoCr films which exhibit a thin and flat perpendicular loop lies in the film plane. The texture of the very thin CoCr films deposited on different underlayers is mainly dependent on the structure and texture of underlayers. The relation between the structure of CoCr and its underlayers is discussed

    4,4′-Dibromo-2-nitro­biphen­yl

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    The title compound, C12H7Br2NO2, a biphenyl derivative, displays a twisted conformation with the two benzene rings making a dihedral angle of 55.34 (14)°. The dihedral angle between the nitro group and its parent benzene ring is 26.8 (2)°. The crystal structure is stabilized by inter­molecular C—H⋯Br and C—H⋯O inter­actions, which lead to the formation of chains propagating along the c-axis direction

    Rice diversity and the joy of eid

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    This brief presents the results of research on the conservation and sustainable use of rice diversity in Bangladesh and how the rice varieties used and planted are intrinsically linked to religious festivals, food culture, land morphology and the climate that shape rice farming/cropping in this region. It highlights the important roles played by Community Seed Wealth Centers (community seed banks) and the Nayakrishi farmers, who manage them, in ensuring the conservation of rice varieties that are in danger of disappearing, and in supplying farmers with diverse, good quality seed. It also demonstrates the key roles played by women farmers as seed custodians and the strategic research and capacity building activities carried out by the Community Seed Wealth Centers
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