Guidelines for the LTO Noise Assessment of Future Civil Supersonic Aircraft in Conceptual Design

One of the most critical regulatory issues related to supersonic flight arises from limitations imposed by community noise acceptability. The most efficient way to ensure that future supersonic aircraft will meet low-noise requirements is the verification of noise emissions from the early stages of the design process. Therefore, this paper suggests guidelines for the Landing and Take-Off (LTO) noise assessment of future civil supersonic aircraft in conceptual design. The supersonic aircraft noise model is based on the semi-empirical equations employed in the early versions of the Aircraft NOise Prediction Program (ANOPP) developed by NASA, whereas sound attenuation due to atmospheric absorption has been considered in accordance with SAE ARP 866 B. The simulation of the trajectory leads to the prediction of the aircraft noise level on ground in terms of several acoustic metrics (LAmax, SEL, PNLTM and EPNL). Therefore, a dedicated validation has been performed, selecting the only available supersonic aircraft of the Aircraft Noise and Performance database (ANP), that is, the Concorde, through the matching with Noise Power Distance (NPD) curves for LAmax and SEL, obtaining a maximum prediction error of +/- 2.19%. At least, an application to departure and approach procedures is reported to verify the first noise estimations with current noise requirements defined by ICAO at the three certification measurement points (sideline, flyover, approach) and to draw preliminary considerations for future low-noise supersonic aircraft design

The Effect of Autologous Platelet Lysate Eye Drops: An In Vivo Confocal Microscopy Study

Purpose. To determine the effectiveness of autologous platelet lysate (APL) eye drops in patients with primary Sjögren syndrome (SS) dry eye, refractory to standard therapy, in comparison with patients treated with artificial tears. We focused on the effect of APL on cornea morphology with the in vivo confocal microscopy (IVCM). Methods. Patients were assigned to two groups: group A used autologous platelet lysate QID, and group B used preservative-free artificial tears QID, for 90 days. Ophthalmological assessments included ocular surface disease index (OSDI), best corrected visual acuity (BCVA), Schirmer test, fluorescein score, and breakup time (BUT). A subgroup of patients in group A underwent IVCM: corneal basal epithelium, subbasal nerves, Langerhans cells, anterior stroma activated keratocytes, and reflectivity were evaluated. Results. 60 eyes of 30 patients were enrolled; in group A (n=20 patients) mean OSDI, fluorescein score, and BUT showed significant improvement compared with group B (n=10 patients). The IVCM showed a significant increase in basal epithelium cells density and subbasal nerve plexus density and number and a decrease in Langerhans cells density (p<0.05). Conclusion. APL was found effective in the treatment of SS dry eye. IVCM seems to be a useful tool to visualize cornea morphologic modifications

Polylysine Enriched Matrices: A Promising Approach for Vascular Grafts

Cardiovascular diseases represent the leading cause of death in developed countries. Modern surgical methods show poor efficiency in the substitution of small-diameter arteries (<6 mm). Due to the difference in mechanical properties between the native artery and the substitute, the behavior of the vessel wall is a major cause of inefficient substitutions. The use of decellularized scaffolds has shown optimal prospects in different applications for regenerative medicine. The purpose of this work was to obtain polylysine-enriched vascular substitutes, derived from decellularized porcine femoral and carotid arteries. Polylysine acts as a matrix cross-linker, increasing the mechanical resistance of the scaffold with respect to decellularized vessels, without altering the native biocompatibility and hemocompatibility properties. The biological characterization showed an excellent biocompatibility, while mechanical tests displayed that the Young’s modulus of the polylysine-enriched matrix was comparable to native vessel. Burst pressure test demonstrated strengthening of the polylysine-enriched matrix, which can resist to higher pressures with respect to native vessel. Mechanical analyses also show that polylysine-enriched vessels presented minimal degradation compared to native. Concerning hemocompatibility, the performed analyses show that polylysine-enriched matrices increase coagulation time, with respect to commercial Dacron vascular substitutes. Based on these findings, polylysine-enriched decellularized vessels resulted in a promising approach for vascular substitution

Constitutionalism and democratic transitions

The book - as the outcome of a research performed by the University of Florence and the United States Institute of Peace of Washington - explores the role of law in the process of democratic transition in South Africa. More specifically it emphasize how constitutional law may contribute to "civilize" apparently unreconcilable conflicts, a part from laying down the foundations of the new legal order and institutions.The book - as the outcome of a research performed by the University of Florence and the United States Institute of Peace of Washington - explores the role of law in the process of democratic transition in South Africa. More specifically it emphasize how constitutional law may contribute to "civilize" apparently unreconcilable conflicts, a part from laying down the foundations of the new legal order and institutions

Constitutionalism and democratic transitions

The book - as the outcome of a research performed by the University of Florence and the United States Institute of Peace of Washington - explores the role of law in the process of democratic transition in South Africa. More specifically it emphasize how constitutional law may contribute to "civilize" apparently unreconcilable conflicts, a part from laying down the foundations of the new legal order and institutions

From Integrated Survey to the Parametric Modeling of Degradations. A Feasible Workflow

This work fits into an international research field about 3D modeling to evaluate the Building Information Model performance for infographic representation of Cultural Heritage. Modeling an historic building involves the creation of parametric objects library starting by data survey. The primary purpose of the research is the translation of these information into a parametric model, through the definition of a proper methodology. The main focus of the research is the creation of parametric object representing the preservation status of material and building components: some recurring schemes of the traditional representation have been identified, in order to find a methodology that leads to link these data to the HBIM (Historic BIM) model, improving their capabilitie

Guidelines for the LTO Noise Assessment of Future Civil Supersonic Aircraft in Conceptual Design

One of the most critical regulatory issues related to supersonic flight arises from limitations imposed by community noise acceptability. The most efficient way to ensure that future supersonic aircraft will meet low-noise requirements is the verification of noise emissions from the early stages of the design process. Therefore, this paper suggests guidelines for the Landing and Take-Off (LTO) noise assessment of future civil supersonic aircraft in conceptual design. The supersonic aircraft noise model is based on the semi-empirical equations employed in the early versions of the Aircraft NOise Prediction Program (ANOPP) developed by NASA, whereas sound attenuation due to atmospheric absorption has been considered in accordance with SAE ARP 866 B. The simulation of the trajectory leads to the prediction of the aircraft noise level on ground in terms of several acoustic metrics (LAmax, SEL, PNLTM and EPNL). Therefore, a dedicated validation has been performed, selecting the only available supersonic aircraft of the Aircraft Noise and Performance database (ANP), that is, the Concorde, through the matching with Noise Power Distance (NPD) curves for LAmax and SEL, obtaining a maximum prediction error of &plusmn;2.19%. At least, an application to departure and approach procedures is reported to verify the first noise estimations with current noise requirements defined by ICAO at the three certification measurement points (sideline, flyover, approach) and to draw preliminary considerations for future low-noise supersonic aircraft design

Guidelines for the LTO Noise Assessment of Future Civil Supersonic Aircraft in Conceptual Design

One of the most critical regulatory issues related to supersonic flight arises from limitations imposed by community noise acceptability. The most efficient way to ensure that future supersonic aircraft will meet low-noise requirements is the verification of noise emissions from the early stages of the design process. Therefore, this paper suggests guidelines for the Landing and Take-Off (LTO) noise assessment of future civil supersonic aircraft in conceptual design. The supersonic aircraft noise model is based on the semi-empirical equations employed in the early versions of the Aircraft NOise Prediction Program (ANOPP) developed by NASA, whereas sound attenuation due to atmospheric absorption has been considered in accordance with SAE ARP 866 B. The simulation of the trajectory leads to the prediction of the aircraft noise level on ground in terms of several acoustic metrics (LAmax, SEL, PNLTM and EPNL). Therefore, a dedicated validation has been performed, selecting the only available supersonic aircraft of the Aircraft Noise and Performance database (ANP), that is, the Concorde, through the matching with Noise Power Distance (NPD) curves for LAmax and SEL, obtaining a maximum prediction error of ±2.19%. At least, an application to departure and approach procedures is reported to verify the first noise estimations with current noise requirements defined by ICAO at the three certification measurement points (sideline, flyover, approach) and to draw preliminary considerations for future low-noise supersonic aircraft design

Unpredicted ecological and ecosystem services of biodiversity. Spontaneous vegetation, hedgerows, and maple trees as useful landscape components to increase predatory mite population in agroecosystems

Rural landscapes have been dramatically simplified and reduced. Large mechanical machinery was adopted and most of the natural helps such as living tutors in the vineyards disappeared or were replaced by cement or steel pillars. In the same way, field margins and hedgerows have also become restricted and simplified. The vegetation in the rural landscape mosaic provides alternative food and overwintering places, maintaining the inestimable importance of biodiversity in providing unexpected ecological services in agroecosystems. An important example could be predatory mites both as species and population density, providing ecological service for biological control such as the two-spotted spider mite attacks. Maple and grape leaf domatia can be hosted by a large number of small invertebrates, including predatory mites such as Phytoseiidae, Laelapidae, and Stigmaeidae. The present study would document the ecological service offered by the presence of predatory mites, especially Phytoseiidae, on wild herbal vegetation and tree species associated with hedgerows in agricultural sites across the Veneto Region (Italy). 25 confirmed species of phytoseiids were revealed. Neoseiulus barkeri results the common species in all plant species habitats studied and with Amblyseius andersoni, Amblyseius rademacheri, Euseius finlandicus, Neoseiulella tiliarum is recorded in most of the study sites. Other species are notable for the preferences of plant species: Neoseiulus cucumeris and Typhlodromus (Anthoseius) verrucosus results associated for elm, meanwhile Neoseiulus aurescens, Paraseiulus soleiger and Phytoseiulus persimilis for maple tree. A positive relationship between the increasing leaf hairiness and the mean number of Phytoseiidae is revealed. The movement of predatory mites from one plant to another could be a necessary condition to support an effective biological control. The reintroduction of the living tutor for vine such as maple and elm and increasing the field margins diversity could improve and maintain the inestimable importance of biodiversity in providing unexpected ecological services in agroecosystems