45 research outputs found
Sunlight supply and gas exchange systems in microalgal bioreactor
The bioreactor with sunlight supply system and gas exchange systems presented has proved feasible in ground tests and shows much promise for space use as a closed ecological life support system device. The chief conclusions concerning the specification of total system needed for a life support system for a man in a space station are the following: (1) Sunlight supply system - compactness and low electrical consumption; (2) Bioreactor system - high density and growth rate of chlorella; and (3) Gas exchange system - enough for O2 production and CO2 assimilation
Compression of Auditory Space during Forward Self-Motion
<div><h3>Background</h3><p>Spatial inputs from the auditory periphery can be changed with movements of the head or whole body relative to the sound source. Nevertheless, humans can perceive a stable auditory environment and appropriately react to a sound source. This suggests that the inputs are reinterpreted in the brain, while being integrated with information on the movements. Little is known, however, about how these movements modulate auditory perceptual processing. Here, we investigate the effect of the linear acceleration on auditory space representation.</p> <h3>Methodology/Principal Findings</h3><p>Participants were passively transported forward/backward at constant accelerations using a robotic wheelchair. An array of loudspeakers was aligned parallel to the motion direction along a wall to the right of the listener. A short noise burst was presented during the self-motion from one of the loudspeakers when the listener’s physical coronal plane reached the location of one of the speakers (null point). In Experiments 1 and 2, the participants indicated which direction the sound was presented, forward or backward relative to their subjective coronal plane. The results showed that the sound position aligned with the subjective coronal plane was displaced ahead of the null point only during forward self-motion and that the magnitude of the displacement increased with increasing the acceleration. Experiment 3 investigated the structure of the auditory space in the traveling direction during forward self-motion. The sounds were presented at various distances from the null point. The participants indicated the perceived sound location by pointing a rod. All the sounds that were actually located in the traveling direction were perceived as being biased towards the null point.</p> <h3>Conclusions/Significance</h3><p>These results suggest a distortion of the auditory space in the direction of movement during forward self-motion. The underlying mechanism might involve anticipatory spatial shifts in the auditory receptive field locations driven by afferent signals from vestibular system.</p> </div
P5A-Type ATPase Cta4p Is Essential for Ca2+ Transport in the Endoplasmic Reticulum of Schizosaccharomyces pombe
This study establishes the role of P5A-type Cta4 ATPase in Ca2+ sequestration in the endoplasmic reticulum by detecting an ATP-dependent, vanadate-sensitive and FCCP insensitive 45Ca2+-transport in fission yeast membranes isolated by cellular fractionation. Specifically, the Ca2+-ATPase transport activity was decreased in ER membranes isolated from cells lacking a cta4+ gene. Furthermore, a disruption of cta4+ resulted in 6-fold increase of intracellular Ca2+ levels, sensitivity towards accumulation of misfolded proteins in ER and ER stress, stimulation of the calcineurin phosphatase activity and vacuolar Ca2+ pumping. These data provide compelling biochemical evidence for a P5A-type Cta4 ATPase as an essential component of Ca2+ transport system and signaling network which regulate, in conjunction with calcineurin, the ER functionality in fission yeast
P-173 A study of cytoskeltons of the hepatocytes in primary culture as a model for the introduction of hepatocytes into a cell cycle for liver regeneration
Characterization of a fission yeast P5-type ATPase homologue that is essential for Ca2+/Mn2+ homeostasis in the absence of P2-type ATPases
Changes in the gut microbiome in relation to the degree of gastric mucosal atrophy before and after Helicobacter pylori eradication
Effects of MPTP on ultrastructures of mouse caudate nucleus and substantia nigra observed with antibodies to tyrosine hydroxylase and dopamine
Quantitative analysis of reduction of aromatic-L-aminoacid decarboxylase- and tyrosine hydroxylase-like immunoreactivities in the nigrostriatal dopaminergic neurons of MPTP-treated mice
Distortion of Auditory Space during Linear Self-Motion
This study investigated how auditory space was represented during linear self-motion. Participants were passively transported forward or backward at constant accelerations by a robotic wheelchair. A short noise burst (30 ms) was presented during self-motion via a loudspeaker aligned parallel with the traveling direction. In Experiment 1, the participants judged in which direction (incoming or outgoing) the noise burst was presented (ie,, two alternative forced choice task). The auditory stimulus perceived to be aligned with the subjective coronal plane shifted in the traveling direction only during forward self-motion. The amount of shift increased with increasing acceleration. In Experiment 2, we examined the accuracy of sound localization during forward self-motion by employing a pointing method. Whereas the auditory stimulus located on the physical coronal plane was almost accurately perceived, those well located in the incoming space were perceived closer to the participants than the physical positions during forward self-motion. These results suggest that the representation of auditory space in the traveling direction was compressed during forward accelerations