Quantum local asymptotic normality based on a new quantum likelihood ratio

We develop a theory of local asymptotic normality in the quantum domain based on a novel quantum analogue of the log-likelihood ratio. This formulation is applicable to any quantum statistical model satisfying a mild smoothness condition. As an application, we prove the asymptotic achievability of the Holevo bound for the local shift parameter.Comment: Published in at http://dx.doi.org/10.1214/13-AOS1147 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org

Auditory Feedback of False Heart Rate for Video Game Experience Improvement

Changes in emotions affect our physiological responses, and perhaps vice versa. We investigate a new game interaction system that uses false heart rate (fHR) feedback to improve the player experience (PX). The fHR feedback presents false HR information to players so that they perceive changes in the presented HR as being a result of alteration in PX. We introduced auditory fHR feedback into game interaction and investigated its effects through an experiment. Participants repeated gameplay of an action game while hearing heartbeat-like sounds and answered questionnaires regarding PX. Some participants heard the heartbeat-like sounds synchronized with their actual HR, whereas others heard the heartbeat-like sounds whose tempo became gradually faster or slower than their actual HR. The results indicated that an accelerating fHR feedback pattern with +5 bpm/min was appropriate for improving PX; participants were able to maintain their motivation to continue the game. The experiment also indicated that it is necessary for participants to perceive the presented heartbeat-like sounds as reflecting their actual HR. Participants did not maintain their motivation when they were told that the presented sounds were not correlated with their actual HR. The present work provides new principles for video game interaction design based on physiological measurements

Experimental Demonstration of Adaptive Quantum State Estimation

The first experimental demonstration of an adaptive quantum state estimation (AQSE) is reported. The strong consistency and asymptotic efficiency of AQSE have been mathematically proven [ A. Fujiwara J. Phys. A 39 12489 (2006)]. In this Letter, the angle of linear polarization of single photons, the phase parameter between the right and the left circularly polarization, is estimated using AQSE, and the strong consistency and asymptotic efficiency are experimentally verified. AQSE will provide a general useful method in both quantum information processing and metrology.Comment: 5pages, 4figure

Dynamic Finite Element Analysis of Impulsive Stress Waves Propagating from Distal End of Femur

The human femur is subjected to an impulsive load at its distal end during daily life. Femoral bone fracture caused by impact loading is common in elderly women. It is important to clarify the dynamic response of the femur and to evaluate the change in its stress state during impact loading. A 3-dimensional model of the femur was prepared in the present study, and the impulsive stress waves propagating from the distal end of the femur were analyzed by the dynamic finite element method. This model showed that the von Mises equivalent stress is large on the anterior and posterior sides of the mid-diaphysis when the impact direction is different from that of the bone axis. As for the femoral neck, the absolute value of minimum principal stress initially increases on the medial side;slightly later the maximum principal stress increases on the lateral side. In this case, the absolute value of the maximum principal stress was found to be larger than that of the minimum principal stress, and the absolute value of the principal stress decreased as the impact angle increased. Further, the femoral neck and the trochanter were shown to have a higher risk of bone fracture when the impact direction is coincident with the bone axis

Capture of Electroweak Multiplet Dark Matter in Neutron Stars

If dark matter has a sizable scattering cross section with nucleons, it can efficiently be captured by a neutron star. Its energy is then transferred to the neutron star as heat through the scattering and annihilation inside the star. This heating effect may be detectable via dedicated temperature observations of nearby old pulsars, providing an alternative method for dark matter searches. In this paper, we show that for electroweak multiplet dark matter this search strategy can probe the parameter region which is out of reach of future dark matter direct detection experiments. To see this systematically, we classify such dark matter candidates in terms of their electroweak charges and investigate the effect of ultraviolet physics by means of higher-dimensional effective operators. We then show that if the effect of ultraviolet physics is sizable, the dark matter-nucleon elastic scattering cross section becomes sufficiently large, whilst if it is suppressed, then the mass splittings among the components of the DM multiplet get small enough so that the inelastic scattering processes are operative. In any case, the electroweak multiplet dark matter particles are efficiently captured in neutron stars, making the search strategy with the temperature observation of old neutron stars promising.Comment: 33 pages, 7 figures, 1 tabl

Voltage- and [ATP]-dependent Gating of the P2X2 ATP Receptor Channel

P2X receptors are ligand-gated cation channels activated by extracellular adenosine triphosphate (ATP). Nonetheless, P2X2 channel currents observed during the steady-state after ATP application are known to exhibit voltage dependence; there is a gradual increase in the inward current upon hyperpolarization. We used a Xenopus oocyte expression system and two-electrode voltage clamp to analyze this “activation” phase quantitatively. We characterized the conductance–voltage relationship in the presence of various [ATP], and observed that it shifted toward more depolarized potentials with increases in [ATP]. By analyzing the rate constants for the channel's transition between a closed and an open state, we showed that the gating of P2X2 is determined in a complex way that involves both membrane voltage and ATP binding. The activation phase was similarly recorded in HEK293 cells expressing P2X2 even by inside-out patch clamp after intensive perfusion, excluding a possibility that the gating is due to block/unblock by endogenous blocker(s) of oocytes. We investigated its structural basis by substituting a glycine residue (G344) in the second transmembrane (TM) helix, which may provide a kink that could mediate “gating.” We found that, instead of a gradual increase, the inward current through the G344A mutant increased instantaneously upon hyperpolarization, whereas a G344P mutant retained an activation phase that was slower than the wild type (WT). Using glycine-scanning mutagenesis in the background of G344A, we could recover the activation phase by introducing a glycine residue into the middle of second TM. These results demonstrate that the flexibility of G344 contributes to the voltage-dependent gating. Finally, we assumed a three-state model consisting of a fast ATP-binding step and a following gating step and estimated the rate constants for the latter in P2X2-WT. We then executed simulation analyses using the calculated rate constants and successfully reproduced the results observed experimentally, voltage-dependent activation that is accelerated by increases in [ATP]

Vortex Creep Heating vs. Dark Matter Heating in Neutron Stars

Dark matter particles captured in neutron stars deposit their energy as heat. This DM heating effect can be observed only if it dominates over other internal heating effects in NSs. In this work, as an example of such an internal heating source, we consider the frictional heating caused by the creep motion of neutron superfluid vortex lines in the NS crust. The luminosity of this heating effect is controlled by the strength of the interaction between the vortex lines and nuclei in the crust, which can be estimated from the many-body calculation of a high-density nuclear system as well as through the temperature observation of old NSs. We show that both the temperature observation and theoretical calculation suggest that the vortex creep heating dominates over the DM heating. The vortex-nuclei interaction must be smaller than the estimated values by several orders of magnitude to overturn this.Comment: 8 pages, 2 figure