A novel phenolic acid from the fruits of <i>Rosa soulieana</i>

<div><p>From the <i>n</i>-BuOH-soluble fraction of a MeOH extract of the fruits of <i>Rosa soulieana</i>, one new phenolic glucoside (<b>1</b>) was isolated along with five known compounds, comprising two lignin glycosides, two flavonoid glycosides and a phenolic glycoside. The chemical structure of the new compound was elucidated by extensive spectroscopic analyses, including ESI-MS, UV, IR, ¹H and ¹³C NMR, DEPT and 2D NMR (HSQC and HMBC). All the isolated compounds were evaluated for their antioxidant activity by using ABTS (2,2′-azino-bis(3-ethylbenzoline-6-sulfonic acid)) assay. Among these compounds, <b>1</b>, <b>3</b> and <b>6</b> exhibited strong scavenging activity in ABTS^√+(SC₅₀ = 102.10, 193.85, 65.38 μmol/L, respectively) compared with the positive control l-ascorbic acid (<i>Vc</i>) (SC₅₀ = 117.16 μmol/L).</p></div

Amphiphilic Diblock Fullerene Derivatives as Cathode Interfacial Layers for Organic Solar Cells

A new amphiphilic diblock fullerene derivative [6,6]-phenyl-C₆₁-butyricacid-4-(9,9,9′,9′-tetrakis­(3-bromopropyl)-9<i>H</i>,9′<i>H</i>-[2,2′-bifluoren]-7-yl)­phenol-(<i>N</i>,<i>N</i>,<i>N</i>-trimethylpropan-1-aminium) bromide (C₆₀-4TPB) was synthesized and applied in organic solar cells. Solvent annealing by toluene could obviously induce the self-assembly of the C₆₀-4TPB layer, which can be tested by the measurements of the water contact angle. After the treatment with toluene, a vertical-like arrangement in the ultrathin layer of the C₆₀-4TPB molecule will be formed between electron-collecting zinc oxide (ZnO) layers and the active layer (blend system of PTB7:PC₇₁BM), leading to the improvement of the interfacial compatibility between the active layer and the ZnO layer. On the top surface of the C₆₀-4TPB layer, the C₆₀ molecules can be expected to induce the enrichment of PC₇₁BM and block the hole, resulting in further increase in the open-circuit voltage (<i>V</i>_OC) and fill factor (FF). After spin-coating the C₆₀-4TPB solutions onto the ZnO layer with a concentration of 0.5 mg/mL in dimethyl sulfoxide, obviously improved performances were obtained with a power conversion efficiency of 8.07%, which can be attributed to the optimized interface morphology between hydrophilic ZnO and hydrophobic PTB7:PC₇₁BM

Light Scattering in Nanoparticle Doped Transparent Polyimide Substrates

Here we demonstrate a simple and effective method of fabricating polymeric scattering substrate for flexible organic light-emitting diodes (OLEDs) that require no costly patterning, etching, or molding processes, aspects that are desirable for the commercialization of large-scale lighting panels. Systematic study of the influences of relative index of refraction, particle size, and doping concentration on transmittance and haze of transparent colorless polyimide (cPI) films was carried out. It was found that the reduction of transmittance and haze of the doped films decreases along with the decrease of the difference of refractive index between the particles and polymer matrix, and it could be compensated by the increase of particle size or doping concentration

Two new polyacetylene glycosides from the roots of <i>Codonopsis tangshen</i> Oliv.

<p>Two new polyacetylene glycosides, tangshenyne A (<b>1</b>) and tangshenyne B (<b>2</b>), along with six known polyacetylenes were isolated from an 85% MeOH extract of the roots of <i>Codonopsis tangshen</i> Oliv. The chemical structures of the new compounds were determined on the basis of extensive spectroscopic analyses, including UV, IR, 1D and 2D NMR (¹H–¹H COSY, HSQC and HMBC) and HR-ESI-MS.</p

1H-NMR spectral data °f the newly isolated compounds 1, 2, and 3 (600 MHz in DMSO-d6, δ in ppm, J in Hz).

<p>1H-NMR spectral data °f the newly isolated compounds 1, 2, and 3 (600 MHz in DMSO-d6, δ in ppm, J in Hz).</p

Cytotoxic Phorbol Esters of <i>Croton tiglium</i>

Chemical investigation of the seeds of <i>Croton tiglium</i> afforded eight new phorbol diesters (three phorbol diesters, <b>1</b>–<b>3</b>, and five 4-deoxy-4α-phorbol diesters, <b>4</b>–<b>8</b>), together with 11 known phorbol diesters (nine phorbol diesters, <b>9</b>–<b>17</b>, and two 4-deoxy-4α-phorbol diesters, <b>18</b> and <b>19</b>). The structures of compounds <b>1</b>–<b>8</b> were determined by spectroscopic data information and chemical degradation experiments. The cytotoxic activities of the phorbol diesters were evaluated against the SNU387 hepatic tumor cell line, and compound <b>3</b> exhibited the most potent activity (IC₅₀ 1.2 μM)

Radical-scavenging activity of the compounds isolated from BPL.

a<p>The SC₅₀ value of each compound was defined as the concentration (μM) that caused 50% scavenging capability of ABTS and DPPH.</p>b<p>Ascorbic acid was used as a positive control.</p

1H-NMR spectral data of the newly isolated compounds 4 and 5 (600 MHz in DMSO-d6, δ in ppm, J in Hz).

<p>1H-NMR spectral data of the newly isolated compounds 4 and 5 (600 MHz in DMSO-d6, δ in ppm, J in Hz).</p

¹³C-NMR spectral data of the newly isolated compounds 1, 2, 3, 4, and 5 (150 MHz in DMSO-d₆, δ in ppm).

<p>¹³C-NMR spectral data of the newly isolated compounds 1, 2, 3, 4, and 5 (150 MHz in DMSO-d₆, δ in ppm).</p

The estrogen biosynthesis activity of the isolated compounds from the BPL.

<p>KGN cells were seeded in 24-well plates and pretreated with test chemicals at 50 μM for 24 h. The cells were then supplemented with 10 nM testosterone for further 24 h, and 17β-estradiol in the culture medium was quantified using a magnetic particle-based 17β-estradiol ELISA. Cont., DMSO control; FSK, 10 μM Forskolin; Let, 1 μM letrozole.</p