176 research outputs found
Design and evaluation of a directional antenna for ocean buoys
A system concept has been developed by Viasat, Inc. and Woods Hole Oceanographic Institution for improving the data
telemetry bandwidth available on ocean buoys. This concept utilizes existing communications satellites as data relay
stations and mechanically steered antenna arrays to achieve increased data rates and improved power efficiency needed for
ocean applications.
This report describes an initial feasibility and design study to determine if a mechanically steered antenna array can
meet the requirements of open ocean buoy applications. To meet the system requirements, an 18-element microstrip
antenna (9-element transmit, 9-element receive) was designed and fabricated under subcontract by Seavey Engineering
Associates, Inc. It operates in the 4-6GHz frequency band (C-band) and provides 14 dB of gain. The 1/2 power beamwidth
is +-t5° in azimuth and elevation. This antenna design, in conjunction with a simple rotating mount, was used to evaluate
the potential of this approach to keep a geostationary satellite in view when mounted on an ocean buoy. The evaluation is
based on laboratory measurements using a magnetic compass and a small stepper motor to maintain antenna orientation
while the complete assembly was rotated and tilted at speeds similar to what would be expected on an offshore buoy
equipped with a stabilizing wind vane.
The results are promising, but less than conclusive because of limitations in the experimental test setup. The recent
introduction of several commercially available mechanically steered antennas designed for use on small boats may provide
a viable alternative to the approach described here with appropriate modification to operate at C-band.Funding was provided by Viasat, Inc., under subcontract No. SC95001 and by a
Cecil H. and Ida M. Green Technology Innovation Award
The Origin of \lya Absorption Systems at ---Implications from the Hubble Deep Field
The Hubble Deep Field images have provided us with a unique chance to relate
statistical properties of high-redshift galaxies to statistical properties of
\lya absorption systems. Combining an {\em empirical} measure of the galaxy
surface density versus redshift with an {\em empirical} measure of the gaseous
extent of galaxies, we predict the number density of \lya absorption systems
that originate in extended gaseous envelopes of galaxies versus redshift. We
show that at least 50% and as much as 100% of observed \lya absorption systems
of W\apg0.32 \AA can be explained by extended gaseous envelops of galaxies.
Therefore, we conclude that known galaxies of known gaseous extent must produce
a significant fraction and perhaps all of \lya absorption systems over a large
redshift range.Comment: 12 pages, 3 figures, accepted for publication in the Astrophysical
Journal, April 10, 2000 issu
Nurses\u27 Alumnae Association Bulletin - Volume 4 Number 7
Welcome Home
Jefferson Unit Honored by Army
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Treasurer Report
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Jefferson Medical College Hospital School of Nursing Faculty
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Synthetic approaches to coronafacic acid, coronamic acid, and coronatine
The phytotoxin coronatine (COR) is a functional mimic of the active plant hormone (+)-7-iso-jasmonoyl-l-isoleucine (JA-IIe), which regulates stress responses. Structurally, COR is composed of a core unit, coronafacic acid (CFA), which is connected to coronamic acid (CMA), via an amide linkage. COR has been found to induce a range of biological activity in plants and based on its biological profile, COR, as well as CFA, and CMA are attractive starting points for agrochemical discovery, resulting in numerous total synthesis efforts. This review will discuss the synthetic approaches towards CFA, CMA and, ultimately COR, to date
Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study
The risk for cardiovascular (CV) disease is increased in rheumatoid arthritis (RA) but data on the burden of coronary atherosclerosis in patients with RA are lacking. We conducted a retrospective case-control study of Olmsted County (MN, USA) residents with RA and new-onset coronary artery disease (CAD) (n = 75) in comparison with age-and sex-matched controls with newly diagnosed CAD (n = 128). Angiographic scores of the first coronary angiogram and data on CV risk factors and CV events on follow-up were obtained by chart abstraction. Patients with RA were more likely to have multi-vessel coronary involvement at first coronary angiogram compared with controls (P = 0.002). Risk factors for CAD including diabetes, hypertension, hyperlipidemia, and smoking history were not significantly different in the two cohorts. RA remained a significant risk factor for multi-vessel disease after adjustment for age, sex and history of hyperlipidemia. The overall rate of CV events was similar in RA patients and controls; however, there was a trend for increased CV death in patients with RA. In a nested cohort of patients with RA and CAD (n = 27), we measured levels of pro-inflammatory CD4(+)CD28(null )T cells by flow cytometry. These T cells have been previously implicated in the pathogenesis of CAD and RA. Indeed, CD4(+)CD28(null )T cells were significantly higher in patients with CAD and co-existent RA than in controls with stable angina (P = 0.001) and reached levels found in patients with acute coronary syndromes. Patients with RA are at increased risk for multi-vessel CAD, although the risk of CV events was not increased in our study population. Expansion of CD4(+)CD28(null )T cells in these patients may contribute to the progression of atherosclerosis
Real-time tomography mooring
A real-time tomography system has been developed which combines ocean acoustic tomography with satellite-based time keeping
and satellite telemetry. The basis of the system is the acoustic tomography transceiver and its associated acoustic navigation grid.
To this basic system, a link to the surface has been added to provide a pathway for telemetry of the tomographic data to shore and a downlink for satellite-derived time which is used to correct the transceiver's clock. The surface buoy contains a GPS receiver, clock comparator, system controller and multiple ID Argos transmitters. Processed tomography signals, transceiver location data time, time drift and surface buoy engineering data are transmitted to satellite using a total of 32 data buffers transmitted every eight minutes. The report describes the real-time tomography system in detail, with particular emphasis on the modifications
implemented to convert the standard tomography instrument to a real-time oceanographic tool.Funding was provided by the Office of Naval Technology
under Contract No. N000-14-C-90-0098
Design and operation of automated ice-tethered profilers for real-time seawater observations in the polar oceans
An automated, easily-deployed Ice-Tethered Profiler (ITP) has been developed for deployment on perennial sea ice in polar oceans to
measure changes in upper ocean temperature and salinity in all seasons. The ITP system consists of three components: a surface
instrument that sits atop an ice floe, a weighted, plastic-jacketed wire-rope tether of arbitrary length (up to 800 m) suspended from the
surface instrument, and an instrumented underwater unit that profiles up and down the wire tether. The profiling underwater unit is
similar in shape and dimension to an ARGO float except that the float's variable-buoyancy system is replaced with a traction drive unit.
Deployment of ITPs may be conducted either from ice caps or icebreakers, utilizing a self contained tripod/winch system that requires no
power. Careful selection of an appropriate multiyear ice floe is needed to prolong the lifetime of the system (up to 3 years depending on
the profiling schedule). Shortly after deployment, each ITP begins profiling the water column at its programmed sampling interval. After
each acquired temperature and salinity profile, the underwater unit (PROCON) transfers the data and engineering files using an inductive
modem to the surface controller (SURFCON). SURFCON also accumulates battery voltages, buoy temperature, and locations from GPS at
specified intervals in status files, and queues that information for transmission at the start of each new day. At frequent intervals, an
Iridium satellite transceiver in the surface package calls and transmits queued status and CTD data files onto a WHOI logger computer,
which are subsequently processed and displayed in near-real time at http://www.whoi.edu/itp. In 2004 and 2005, three ITP prototypes
were deployed in the Arctic Ocean. Each system was programmed with accelerated sampling schedules of multiple one-way traverses per
day between 10 and 750-760 m depth in order to quickly evaluate endurance and component fatigue. Two of the ITPs are continuing to
function after more than 10 months and 1200 profiles. Larger motor currents are observed at times of fast ice floe motion when larger
wire angles develop and drag forces on the profiler are increased. The CTD profile data so far obtained document interesting spatial
variations in the major water masses of the Beaufort Gyre, show the double-diffusive thermohaline staircase that lies above the warm,
salty Atlantic layer, and many mesoscale eddys. Deployed together with CRREL Ice Mass Balance (IMB) buoys, these ITP systems also
operate as part of an Ice Based Observatory (IBO). Data returned from an array of IBOs within an Arctic Observing Network will provide
valuable real time observations, support studies of ocean processes, and facilitate numerical model initialization and validation.Funding was provided by the National Science Foundation under Contract Nos. OCE-0324233 and ARC-0519899
Scope for Credit Risk Diversification
This paper considers a simple model of credit risk and derives the limit distribution of losses under different assumptions regarding the structure of systematic risk and the nature of exposure or firm heterogeneity. We derive fat-tailed correlated loss distributions arising from Gaussian risk factors and explore the potential for risk diversification. Where possible the results are generalised to non-Gaussian distributions. The theoretical results indicate that if the firm parameters are heterogeneous but come from a common distribution, for sufficiently large portfolios there is no scope for further risk reduction through active portfolio management. However, if the firm parameters come from different distributions, then further risk reduction is possible by changing the portfolio weights. In either case, neglecting parameter heterogeneity can lead to underestimation of expected losses. But, once expected losses are controlled for, neglecting parameter heterogeneity can lead to overestimation of risk, whether measured by unexpected loss or value-at-risk
The Lantern Vol. 38, No. 2, Spring 1972
⢠Summer II ⢠For a True Romantic ⢠The Lyre Neglected ⢠Hands ⢠To a Friend ⢠Sleep ⢠The Wind\u27s Confusing Sounds ⢠The Garden ⢠The Child Has Come Among Us ⢠The River and the Sea ⢠The Ice ⢠La Lamentation de la Fleur ⢠Nous Sommes ⢠Upon Becoming ⢠See! ⢠Feeling November ⢠Transience ⢠Clear ⢠Isotopes of Reality ⢠Just Yesterday ⢠Emergence ⢠Push ⢠The Way Love Starts ⢠Poetic Prosy ⢠An Agreement ⢠Spring 1930 ⢠The Summers of \u2759, \u2760, \u2761 ⢠Ode to Optometry ⢠The Easter Bunny - Noble Beasthttps://digitalcommons.ursinus.edu/lantern/1100/thumbnail.jp
Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer\u27s disease.
Proteomic studies have identified moesin (MSN), a protein containing a four-point-one, ezrin, radixin, moesin (FERM) domain, and the receptor CD44 as hub proteins found within a coexpression module strongly linked to Alzheimer\u27s disease (AD) traits and microglia. These proteins are more abundant in Alzheimer\u27s patient brains, and their levels are positively correlated with cognitive decline, amyloid plaque deposition, and neurofibrillary tangle burden. The MSN FERM domain interacts with the phospholipid phosphatidylinositol 4,5-bisphosphate (PI
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