1,455 research outputs found
The Conundrum of Online Prescription Drug Promotion Comment on "Trouble Spots in Online Direct-to-Consumer Prescription Drug Promotion: A Content Analysis of FDA Warning Letters"
In the Wake of the Storm: Environment, Disaster, and Race After Katrina
Studies evidence of environmental disparities by which poor and minority communities are disproportionately exposed to disasters, are less prepared, and have less access to relief agencies. Makes recommendations for preparedness and environmental justice
Economic Feasibility of Ethanol Production from Sweet Sorghum Juice in Texas
The economic feasibility of producing ethanol from sweet sorghum juice is projected using Monte Carlo simulation models to estimate the price ethanol plants will likely have to pay for sweet sorghum and the uncertain returns for ethanol plants. Ethanol plants in high yielding regions will likely generate returns on assets of 11%-12% and in low yield areas the returns on assets will be less than 10%.Sweet Sorghum, Ethanol, Monte Carlo Simulation, Agribusiness, Agricultural Finance, Crop Production/Industries, Farm Management, Risk and Uncertainty, D20 G10 D81 C15,
Banding pattern indicative of echinococcosis in a commercial cysticercosis western blot
<p>Abstract</p> <p>Objective</p> <p>A commercial cysticercosis Western blot was evaluated for serological cross-reactivity of sera from patients with alveolar (AE) and cystic echinococcosis (CE).</p> <p>Methods</p> <p>A total of 161 sera were examined, including 31 sera from AE-patients, 11 sera from CE-patients, 9 sera from patients with other parasitic diseases and 109 sera from patients with unrelated medical conditions. All AE-and CE-sera were also examined by the echinococcosis Western blot.</p> <p>Results</p> <p>More sera from patients with AE than with CE showed cross-reactivity in the form of ladder-like patterns ("Mikado aspect") and untypical bands at 6-8 kDa (71% and 77.4% versus 27.3% and 45.5%, respectively). In contrast, triplets of bands in the area above 50 kDa and between 24 and 39-42 kDa were more frequent in CE than in AE sera. The fuzzy band at 50-55 kDa typical for cysticercosis was absent in all AE and CE sera.</p> <p>Conclusions</p> <p>Atypical banding patterns in the cysticercosis Western blot should raise the suspicion of a metacestode infection different from Taenia solium, i.e. Echinococcus multilocularis or E. granulosus, especially when the Mikado aspect and an altered 6-8 kDa band is visible in the absence of a fuzzy 50-55 kDa band.</p
Candidate screening for the recruitment of critical research and development workers - a report and preliminary results with evidence from experimental data from German high-tech firms
The report focuses on résumé-based screening strategies for the recruitment of highly qualified research and development (R&D) workers (critical R&D workers) in high-tech firms. We investigate which kinds of professional background, job-related experience, motivations, specific skills, and previous inventive activity make a candidate attractive for firms specializing in clean technology or mechanical elements. The report is based on a combination of survey and experimental data collected from 194 HR decision makers in German high-tech firms and from 89 technology experts in the clean technology and mechanical elements fields. A mixed logit model is used to analyse hiring preferences because this model allows us to deal with repeated choices. We find that HR decision makers prefer candidates with technology-specific patenting experience, an engineering background, analytical thinking skills, and a strong desire to develop path-breaking technologies. Furthermore, no one-size-fits-all candidate exists that is equally preferred in both technology fields. HR decision makers in mechanical element firms prefer specialists to generalists, whereas those in clean technology attach special importance to a candidate’s orientation towards environmental concerns and sustainability
The Environmental “Riskscape” and Social Inequality: Implications for Explaining Maternal and Child Health Disparities
BACKGROUND: Research indicates that the double jeopardy of exposure to environmental hazards combined with place-based stressors is associated with maternal and child health (MCH) disparities. OBJECTIVE AND DISCUSSION: Our aim is to present evidence that individual-level and place-based psychosocial stressors may compromise host resistance such that environmental pollutants would have adverse health effects at relatively lower doses, thus partially explaining MCH disparities, particularly poor birth outcomes. Allostatic load may be a physiologic mechanism behind the moderation of the toxic effect of environmental pollutants by social stressors. We propose a conceptual framework for holistic approaches to future MCH research that elucidates the interplay of psychosocial stressors and environmental hazards in order to better explain drivers of MCH disparities. CONCLUSION: Given the complexity of the link between environmental factors and MCH disparities, a holistic approach to future MCH research that seeks to untangle the double jeopardy of chronic stressors and environmental hazard exposures could help elucidate how the interplay of these factors shapes persistent racial and economic disparities in MCH
Improving the Design of U-Beams for Indiana
The use of prestressed U-beams, developed as an economical and aesthetic alternative to traditional I-beams, is becoming increasingly common. While U-beams are seeing increased use, questions have arisen in the design of bridges utilizing this girder type. Specific issues include live load distribution, bridge deck behavior, and debonding limits. First, since the U-beam is a new girder type, limited guidance exists for the live load distributions to be used in design. Second, due to the increased stiffness and strength of this girder, fewer girder lines are required resulting in increased deck spans. Finally, current AASHTO debonding limits severely restrict the efficiency and economy of the section. The objective of this research program is to develop design strategies to improve the efficiency and optimize the design of the Indiana modified U-beam with a focus on the concerns related to the design of U-beams. In particular, this research program will evaluate the live load distribution appropriate for the design of U-beams, assess the behavior and design of the bridge deck when supported by U-beams, and evaluate both the shear strength and shear design of the composite U-beam system. It is important that the strength strength of pretensioned concrete beams with debonded strand be fully evaluated. Five phases of research were conducted. The first phase consisted of evaluation of a U-beam bridge constructed in Indianapolis, Indiana to assess the live load distribution factors and flexural deck behavior of this bridge. The second phase evaluated the effectiveness of debonding sheathing to ensure that proper debonding is being achieved. The third phase evaluated the influence of the percentage of debonded strands on shear strength using rectangular and I-shaped cross sections to investigate flexure-shear and web-shear strengths, respectively. While this phase concentrated on the shear strength resisted by the concrete, the influence of transverse reinforcement was also evaluated. The fourth phase evaluated the influence of varying strength concretes, which are commonly used in composite sections, on shear strength. Finally, the fifth phase evaluated the shear strength of a 50% debonded U-beam both with and without transverse reinforcement. From the results, an improved understanding of the influence of debonding on shear strength is obtained. Recommendations are provided to improve the analysis, design, and construction of U-beams as well as the design and construction of girders utilizing debonded strand in general
Effects of the Neutron Spin-Orbit Density on Nuclear Charge Density in Relativistic Models
The neutron spin-orbit density contributes to the nuclear charge density as a
relativistic effect. The contribution is enhanced by the effective mass
stemming from the Lorentz-scalar potential in relativistic models. This
enhancement explains well the difference between the cross sections of elastic
electron scattering off Ca and Ca which was not reproduced in
non-relativistic models. The spin-orbit density will be examined in more detail
in electron scattering off unstable nuclei which would be available in the
future.Comment: 4 pages with 3 eps figures, revte
The TLR4 ligands MRP8 and MRP14 in the diagnosis and pathogenesis of systemic onset juvenile idiopathic arthritis
Public health implications of 1990 air toxics concentrations across the United States.
Occupational and toxicological studies have demonstrated adverse health effects from exposure to toxic air contaminants. Data on outdoor levels of toxic air contaminants have not been available for most communities in the United States, making it difficult to assess the potential for adverse human health effects from general population exposures. Emissions data from stationary and mobile sources are used in an atmospheric dispersion model to estimate outdoor concentrations of 148 toxic air contaminants for each of the 60,803 census tracts in the contiguous United States for 1990. Outdoor concentrations of air toxics were compared to previously defined benchmark concentrations for cancer and noncancer health effects. Benchmark concentrations are based on standard toxicological references and represent air toxic levels above which health risks may occur. The number of benchmark concentrations exceeded by modeled concentrations ranged from 8 to 32 per census tract, with a mean of 14. Estimated concentrations of benzene, formaldehyde, and 1,3-butadiene were greater than cancer benchmark concentrations in over 90% of the census tracts. Approximately 10% of all census tracts had estimated concentrations of one or more carcinogenic HAPs greater than a 1-in-10,000 risk level. Twenty-two pollutants with chronic toxicity benchmark concentrations had modeled concentrations in excess of these benchmarks, and approximately 200 census tracts had a modeled concentration 100 times the benchmark for at least one of these pollutants. This comprehensive assessment of air toxics concentrations across the United States indicates hazardous air pollutants may pose a potential public health problem
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