Verbing and nouning in French : toward an ecologically valid approach to sentence processing

La présente thèse utilise la technique des potentiels évoqués afin d’étudier les méchanismes neurocognitifs qui sous-tendent la compréhension de la phrase. Plus particulièrement, cette recherche vise à clarifier l’interaction entre les processus syntaxiques et sémantiques chez les locuteurs natifs et les apprenants d’une deuxième langue (L2). Le modèle “syntaxe en premier” (Friederici, 2002, 2011) prédit que les catégories syntaxiques sont analysées de façon précoce: ce stade est reflété par la composante ELAN (Early anterior negativity, Négativité antérieure gauche), qui est induite par les erreurs de catégorie syntaxique. De plus, ces erreurs semblent empêcher l’apparition de la composante N400 qui reflète les processus lexico-sémantiques. Ce phénomène est défini comme le bloquage sémantique (Friederici et al., 1999). Cependant, la plupart des études qui observent la ELAN utilisent des protocoles expérimentaux problématiques dans lesquels les différences entre les contextes qui précèdent la cible pourraient être à l’origine de résultats fallacieux expliquant à la fois l’apparente “ELAN” et l’absence de N400 (Steinhauer & Drury, 2012). La première étude rééevalue l’approche de la “syntaxe en premier” en adoptant un paradigme expériemental novateur en français qui introduit des erreurs de catégorie syntaxique et les anomalies de sémantique lexicale. Ce dessin expérimental équilibré contrôle à la fois le mot-cible (nom vs. verbe) et le contexte qui le précède. Les résultats récoltés auprès de locuteurs natifs du français québécois ont révélé un complexe N400-P600 en réponse à toutes les anomalies, en contradiction avec les prédictions du modèle de Friederici. Les effets additifs des manipulations syntaxique et sémantique sur la N400 suggèrent la détection d’une incohérence entre la racine du mot qui avait été prédite et la cible, d’une part, et l’activation lexico-sémantique, d’autre part. Les réponses individuelles se sont pas caractérisées par une dominance vers la N400 ou la P600: au contraire, une onde biphasique est présente chez la majorité des participants. Cette activation peut donc être considérée comme un index fiable des mécanismes qui sous-tendent le traitement des structures syntagmatiques. La deuxième étude se concentre sur les même processus chez les apprenants tardifs du français L2. L’hypothèse de la convergence (Green, 2003 ; Steinhauer, 2014) prédit que les apprenants d’une L2, s’ils atteignent un niveau avancé, mettent en place des processus de traitement en ligne similaires aux locuteurs natifs. Cependant, il est difficile de considérer en même temps un grand nombre de facteurs qui se rapportent à leurs compétences linguistiques, à l’exposition à la L2 et à l’âge d’acquisition. Cette étude continue d’explorer les différences inter-individuelles en modélisant les données de potentiels-évoqués avec les Forêts aléatoires, qui ont révélé que le pourcentage d’explosition au français ansi que le niveau de langue sont les prédicteurs les plus fiables pour expliquer les réponses électrophysiologiques des participants. Plus ceux-ci sont élevés, plus l’amplitude des composantes N400 et P600 augmente, ce qui confirme en partie les prédictions faites par l’hypothèse de la convergence. En conclusion, le modèle de la “syntaxe en premier” n’est pas viable et doit être remplacé. Nous suggérons un nouveau paradigme basé sur une approche prédictive, où les informations sémantiques et syntaxiques sont activées en parallèle dans un premier temps, puis intégrées via un recrutement de mécanismes contrôlés. Ces derniers sont modérés par les capacités inter-individuelles reflétées par l’exposition et la performance.The present thesis uses event-related potentials (ERPs) to investigate neurocognitve mechanisms underlying sentence comprehension. In particular, these two experiments seek to clarify the interplay between syntactic and semantic processes in native speakers and second language learners. Friederici’s (2002, 2011) “syntax-first” model predicts that syntactic categories are analyzed at the earliest stages of speech perception reflected by the ELAN (Early left anterior negativity), reported for syntactic category violations. Further, syntactic category violations seem to prevent the appearance of N400s (linked to lexical-semantic processing), a phenomenon known as “semantic blocking” (Friederici et al., 1999). However, a review article by Steinhauer and Drury (2012) argued that most ELAN studies used flawed designs, where pre-target context differences may have caused ELAN-like artifacts as well as the absence of N400s. The first study reevaluates syntax-first approaches to sentence processing by implementing a novel paradigm in French that included correct sentences, pure syntactic category violations, lexical-semantic anomalies, and combined anomalies. This balanced design systematically controlled for target word (noun vs. verb) and the context immediately preceding it. Group results from native speakers of Quebec French revealed an N400-P600 complex in response to all anomalous conditions, providing strong evidence against the syntax-first and semantic blocking hypotheses. Additive effects of syntactic category and lexical-semantic anomalies on the N400 may reflect a mismatch detection between a predicted word-stem and the actual target, in parallel with lexical-semantic retrieval. An interactive rather than additive effect on the P600 reveals that the same neurocognitive resources are recruited for syntactic and semantic integration. Analyses of individual data showed that participants did not rely on one single cognitive mechanism reflected by either the N400 or the P600 effect but on both, suggesting that the biphasic N400-P600 ERP wave can indeed be considered to be an index of phrase-structure violation processing in most individuals. The second study investigates the underlying mechanisms of phrase-structure building in late second language learners of French. The convergence hypothesis (Green, 2003; Steinhauer, 2014) predicts that second language learners can achieve native-like online- processing with sufficient proficiency. However, considering together different factors that relate to proficiency, exposure, and age of acquisition has proven challenging. This study further explores individual data modeling using a Random Forests approach. It revealed that daily usage and proficiency are the most reliable predictors in explaining the ERP responses, with N400 and P600 effects getting larger as these variables increased, partly confirming and extending the convergence hypothesis. This thesis demonstrates that the “syntax-first” model is not viable and should be replaced. A new account is suggested, based on predictive approaches, where semantic and syntactic information are first used in parallel to facilitate retrieval, and then controlled mechanisms are recruited to analyze sentences at the interface of syntax and semantics. Those mechanisms are mediated by inter-individual abilities reflected by language exposure and performance

Growing Random Forests reveals that exposure and proficiency best account for 2 individual variability in L2 (and L1) brain potentials for syntax and semantics

Late second language (L2) learners report difficulties in specific linguistic areas such as syntactic processing, presumably because brain plasticity declines with age (following the critical period hypothesis). While there is also evidence that L2 learners can achieve native-like online-processing with sufficient proficiency (following the convergence hypothesis), considering multiple mediating factors and their impact on language processing has proven challenging. We recorded EEG while native (n = 36) and L2-speakers of French (n = 40) read sentences that were either well-formed or contained a syntactic-category error. a lexical-semantic anomaly, or both. Consistent with the critical period hypothesis, group differences revealed that while native speakers elicited a biphasic N400-P600 in response to ungrammatical sentences, L2 learners as a group only elicited an N400. However, individual data modeling using a Random Forests approach revealed that language exposure and proficiency are the most reliable predictors in explaining ERP responses, with N400 and P600 effects becoming larger as exposure to French as well as proficiency increased, as predicted by the convergence hypothesis

Verbing nouns and nouning verbs: Using a balanced design provides ERP evidence against “syntax-first” approaches to sentence processing

In this event-related potential (ERP) study we reevaluate syntax-first approaches to sentence processing by implementing a novel paradigm in French that includes correct sentences, pure syntactic category violations, lexical-semantic anomalies, and combined anomalies. Our balanced design systematically controlled for target word (noun vs. verb) and the context immediately preceding it. Group results from 36 native speakers of Quebec French revealed that, up to 300 ms, ERPs elicited by syntactic category violations were comparable with ERP responses to correct sentences, showing that there is no early activation reflecting syntactic category identification. Instead, in response to all anomalous conditions, we observed an N400 followed by a P600. Combined anomalies yielded additive effects of syntactic category and lexical-semantic anomalies on the N400, and a large P600 effect similar to the one observed in the pure syntactic condition. These results provide strong evidence against the hypothesis that (i) syntactic categories are processed first, and (ii) that syntactic category errors “block” lexical-semantic processing. Further, the N400 effect in response to pure syntactic category violations reflects a mismatch detection between a predicted word-stem and the actual target. This mechanism takes place simultaneously (and potentially in parallel) with lexical-semantic processing. In contrast, an interaction of syntax and semantics for the P600 reveals that the same neurocognitive resources are recruited for syntactic and semantic integration, both promoted by the implementation of an acceptability judgement task in our design. Additional analyses of individual data complemented these observations: during sentence processing, participants did not rely on one single cognitive mechanism reflected by either the N400 or the P600 effect but on both, suggesting that the biphasic N400-P600 ERP wave can indeed be considered to be an index of phrase-structure violations in most individuals, at least if they are realized on content words

Long-distance anticipatory vowel-to-vowel assimilatory effects in French and Japanese

This paper examines language-specific differences in anticipatory vowel-to-vowel coarticulation using two non-stress languages. Native speakers of Standard French (n=6) and Tokyo Japanese (n=5) served as subjects to a production study. To investigate possible long-distance effects between and beyond adjacent vowels, linguistic material consisting of /ba.bV/ and /ba.ba.bV/ was embedded within a carrier sentence in each language. The word-final trigger vowel (V) is /a/, /i/ or /u/. Acoustic analysis of continuous F1 and F2 trajectories as well as singlepoint formant measurements revealed opposite patterns in the two languages. Strong anticipatory effects in vowels up to 2 preceding syllables were observed in French. However, Japanese displayed few statistically significant anticipatory effects in any vowel preceding any trigger. We interpret the results as an indication that there are two rather different types of contextual phonetic variability. We also assert not all phonetic assimilatory effects in “coarticulation” are due to articulatory overlap.postprin

The priming of priming : Evidence that the N400 reflects context-dependent post-retrieval word integration in working memory

Which cognitive processes are reflected by the N400 in ERPs is still controversial. Various recent articles(Lau et al., 2008; Brouwer et al., 2012) have revived the idea that only lexical pre-activation processes(such as automatic spreading activation, ASA) are strongly supported, while post-lexical integrative pro-cesses are not. Challenging this view, the present ERP study replicates a behavioral study by McKoon andRatcliff (1995) who demonstrated that a prime-target pair such as finger − hand shows stronger primingwhen a majority of other pairs in the list share the analogous semantic relationship (here: part-whole),even at short stimulus onset asynchronies (250 ms). We created lists with four different types of semanticrelationship (synonyms, part-whole, category-member, and opposites) and compared priming for pairsin a consistent list with those in an inconsistent list as well as unrelated items. Highly significant N400reductions were found for both relatedness priming (unrelated vs. inconsistent) and relational priming(inconsistent vs. consistent). These data are taken as strong evidence that N400 priming effects are notexclusively carried by ASA-like mechanisms during lexical retrieval but also include post-lexical inte-gration in working memory. We link the present findings to a neurocomputational model for relationalreasoning (Knowlton et al., 2012) and to recent discussions of context-dependent conceptual activations(Yee and Thompson-Schill, 2016)

Targeted rapid amplification of cDNA ends (T-RACE)—an improved RACE reaction through degradation of non-target sequences

Amplification of the 5′ ends of cDNA, although simple in theory, can often be difficult to achieve. We describe a novel method for the specific amplification of cDNA ends. An oligo-dT adapter incorporating a dUTP-containing PCR primer primes first-strand cDNA synthesis incorporating dUTP. Using the Cap finder approach, another distinct dUTP containing adapter is added to the 3′ end of the newly synthesized cDNA. Second-strand synthesis incorporating dUTP is achieved by PCR, using dUTP-containing primers complimentary to the adapter sequences incorporated in the cDNA ends. The double-stranded cDNA-containing dUTP serves as a universal template for the specific amplification of the 3′ or 5′ end of any gene. To amplify the ends of cDNA, asymmetric PCR is performed using a single gene-specific primer and standard dNTPs. The asymmetric PCR product is purified and non-target transcripts containing dUTP degraded by Uracil DNA glycosylase, leaving only those transcripts produced during the asymmetric PCR. Subsequent PCR using a nested gene-specific primer and the 3′ or 5′ T-RACE primer results in specific amplification of cDNA ends. This method can be used to specifically amplify the 3′ and 5′ ends of numerous cDNAs from a single cDNA synthesis reaction

Revisiting Date and Party Hubs: Novel Approaches to Role Assignment in Protein Interaction Networks

The idea of 'date' and 'party' hubs has been influential in the study of protein-protein interaction networks. Date hubs display low co-expression with their partners, whilst party hubs have high co-expression. It was proposed that party hubs are local coordinators whereas date hubs are global connectors. Here we show that the reported importance of date hubs to network connectivity can in fact be attributed to a tiny subset of them. Crucially, these few, extremely central, hubs do not display particularly low expression correlation, undermining the idea of a link between this quantity and hub function. The date/party distinction was originally motivated by an approximately bimodal distribution of hub co-expression; we show that this feature is not always robust to methodological changes. Additionally, topological properties of hubs do not in general correlate with co-expression. Thus, we suggest that a date/party dichotomy is not meaningful and it might be more useful to conceive of roles for protein-protein interactions rather than individual proteins. We find significant correlations between interaction centrality and the functional similarity of the interacting proteins.Comment: 27 pages, 5 main figures, 4 supplementary figure

Atmospheric Escape From Three Terrestrial Planets in the L 98-59 System

A critically important process affecting the climate evolution and potential habitability of an exoplanet is atmospheric escape, in which high-energy radiation from a star drives the escape of hydrogen atoms and other light elements from a planet's atmosphere. L 98-59 is a benchmark system for studying such atmospheric processes, with three transiting terrestrial-size planets receiving Venus-like instellations (4-25 S$_\oplus$) from their M3 host star. We use the VPLanet model to simulate the evolution of the L 98-59 system and the atmospheric escape of its inner three small planets, given different assumed initial water quantities. We find that, regardless of their initial water content, all three planets accumulate significant quantities of oxygen due to efficient water photolysis and hydrogen loss. All three planets also receive enough XUV flux to drive rapid water loss, which considerably affects their developing climates and atmospheres. Even in scenarios of low initial water content, our results suggest that the James Webb Space Telescope (JWST) will be sensitive to observations of retained oxygen on the L 98-59 planets in its future scheduled observations, with planets b and c being the most likely targets to possess an extended atmosphere. Our results constrain the atmospheric evolution of these small rocky planets, and they provide context for current and future observations of the L 98-59 system to generalize our understanding of multi-terrestrial planet systems.Comment: 17 pages, 7 figures, accepted for publication in the Astrophysical Journa