928 research outputs found

    Interplay between function and structure in complex networks

    Get PDF
    We show that abrupt structural transitions can arise in functionally optimal networks, driven by small changes in the level of transport congestion. Our results offer an explanation as to why so many diverse species of network structure arise in Nature (e.g. fungal systems) under essentially the same environmental conditions. Our findings are based on an exactly solvable model system which mimics a variety of biological and social networks. We then extend our analysis by introducing a novel renormalization scheme involving cost motifs, to describe analytically the average shortest path across multiple-ring-and-hub networks. As a consequence, we uncover a 'skin effect' whereby the structure of the inner multi-ring core can cease to play any role in terms of determining the average shortest path across the network.Comment: Expanded version of physics/0508228 with additional new result

    Performance of the Now Malaria rapid diagnostic test with returned travellers: a 2-year retrospective study in a French teaching hospital

    Get PDF
    ABSTRACTMalaria caused by Plasmodium falciparum remains the major life-threatening parasitic infection in the world. The number of cases in non-endemic countries continues to increase, and it is important that misdiagnosis of malaria should not occur, especially in non-immune travellers, because of the high risk of a fatal outcome. In a retrospective study of 399 sera, the Now Malaria rapid test was compared with the quantitative buffy coat (QBC) test and microbiological examination of thin blood films. Compared with the QBC test and thin blood films, the Now Malaria test had sensitivity and specificity values of 96.4% and 97%, respectively, for the detection of pure P. falciparum infection. A negative predictive value of 99.4% allows this test to be included in diagnostic strategies for patients presenting with clinical suspicion of malaria. Two false-negative results were associated with low levels of parasitaemia in the specimens. Thus, use of the Now Malaria test alone to detect P. falciparum infection in non-endemic countries could lead to misdiagnosis of malaria. This rapid diagnostic test should therefore be performed in association with another prompt traditional method such as examination of thin blood films

    High basal melting forming a channel at the grounding line of Ross Ice Shelf, Antarctica

    Get PDF
    Antarctica's ice shelves are thinning at an increasing rate, affecting their buttressing ability. Channels in the ice shelf base unevenly distribute melting, and their evolution provides insight into changing subglacial and oceanic conditions. Here we used phase-sensitive radar measurements to estimate basal melt rates in a channel beneath the currently stable Ross Ice Shelf. Melt rates of 22.2 ± 0.2 m a−1 (>2500% the overall background rate) were observed 1.7 km seaward of Mercer/Whillans Ice Stream grounding line, close to where subglacial water discharge is expected. Laser altimetry shows a corresponding, steadily deepening surface channel. Two relict channels to the north suggest recent subglacial drainage reorganization beneath Whillans Ice Stream approximately coincident with the shutdown of Kamb Ice Stream. This rapid channel formation implies that shifts in subglacial hydrology may impact ice shelf stability

    Large closed queueing networks in semi-Markov environment and its application

    Full text link
    The paper studies closed queueing networks containing a server station and kk client stations. The server station is an infinite server queueing system, and client stations are single-server queueing systems with autonomous service, i.e. every client station serves customers (units) only at random instants generated by a strictly stationary and ergodic sequence of random variables. The total number of units in the network is NN. The expected times between departures in client stations are (Nμj)1(N\mu_j)^{-1}. After a service completion in the server station, a unit is transmitted to the jjth client station with probability pjp_{j} (j=1,2,...,k)(j=1,2,...,k), and being processed in the jjth client station, the unit returns to the server station. The network is assumed to be in a semi-Markov environment. A semi-Markov environment is defined by a finite or countable infinite Markov chain and by sequences of independent and identically distributed random variables. Then the routing probabilities pjp_{j} (j=1,2,...,k)(j=1,2,...,k) and transmission rates (which are expressed via parameters of the network) depend on a Markov state of the environment. The paper studies the queue-length processes in client stations of this network and is aimed to the analysis of performance measures associated with this network. The questions risen in this paper have immediate relation to quality control of complex telecommunication networks, and the obtained results are expected to lead to the solutions to many practical problems of this area of research.Comment: 35 pages, 1 figure, 12pt, accepted: Acta Appl. Mat

    The structural and dynamic responses of Stange Ice Shelf to recent environmental change

    Get PDF
    Stange Ice Shelf is the most south-westerly ice shelf on the Antarctic Peninsula, a region where positive trends in atmospheric and oceanic temperatures have been recently documented. In this paper, we use a range of remotely sensed datasets to evaluate the structural and dynamic responses of Stange Ice Shelf to these environmental changes. Ice shelf extent and surface structures were examined at regular intervals from optical and radar satellite imagery between 1973 and 2011. Surface speeds were estimated in 1989, 2004 and 2010 by tracking surface features in successive satellite images. Surface elevation change was estimated using radar altimetry data acquired between 1992 and 2008 by the European Remote Sensing Satellite (ERS) -1, -2 and Envisat. The mean number of surface melt days was estimated using the intensity of backscatter from Envisat’s Advanced Synthetic Aperture Radar instrument between 2006 and 2012. These results show significant shear fracturing in the southern portion of the ice shelf linked to enhanced flow speed as a consequence of measured thinning. However, we conclude that, despite the observed changes, Stange Ice Shelf is currently stable

    Evolution of the Seasonal Surface Mixed Layer of the Ross Sea, Antarctica, Observed With Autonomous Profiling Floats

    Get PDF
    Oceanographic conditions on the continental shelf of the Ross Sea, Antarctica, affect sea ice production, Antarctic Bottom Water formation, mass loss from the Ross Ice Shelf, and ecosystems. Since ship access to the Ross Sea is restricted by sea ice in winter, most upper ocean measurements have been acquired in summer. We report the first multiyear time series of temperature and salinity throughout the water column, obtained with autonomous profiling floats. Seven Apex floats were deployed in 2013 on the midcontinental shelf, and six Air‐Launched Autonomous Micro Observer floats were deployed in late 2016, mostly near the ice shelf front. Between profiles, most floats were parked on the seabed to minimize lateral motion. Surface mixed layer temperatures, salinities, and depths, in winter were −1.8 °C, 34.34, and 250–500 m, respectively. Freshwater from sea ice melt in early December formed a shallow (20 m) surface mixed layer, which deepened to 50–80 m and usually warmed to above −0.5 °C by late January. Upper‐ocean freshening continued throughout the summer, especially in the eastern Ross Sea and along the ice shelf front. This freshening requires substantial lateral advection that is dominated by inflow from melting of sea ice and ice shelves in the Amundsen Sea and by inputs from the Ross Ice Shelf. Changes in upper‐ocean freshwater and heat content along the ice shelf front in summer affect cross‐ice front advection, ice shelf melting, and calving processes that determine the rate of mass loss from the grounded Antarctic Ice Sheet in this sector

    Personalised service? Changing the role of the government librarian

    Get PDF
    Investigates the feasibility of personalised information service in a government department. A qualitative methodology explored stakeholder opinions on the remit, marketing, resourcing and measurement of the service. A questionnaire and interviews gathered experiences of personalised provision across the government sector. Potential users were similarly surveyed to discuss how the service could meet their needs. Data were analysed using coding techniques to identify emerging theory. Lessons learned from government librarians centred on clarifying requirements, balancing workloads and selective marketing. The user survey showed low usage and awareness of existing specialist services, but high levels of need and interest in services repackaged as a tailored offering. Fieldwork confirmed findings from the literature on the scope for adding value through information management advice, information skills training and substantive research assistance and the need to understand business processes and develop effective partnerships. Concluding recommendations focus on service definition, strategic marketing, resource utilisation and performance measurement

    On the error term in Weyl's law for the Heisenberg manifolds (II)

    Full text link
    In this paper we study the mean square of the error term in the Weyl's law of an irrational (2l+1)(2l+1)-dimensional Heisenberg manifold . An asymptotic formula is established
    corecore