1,997 research outputs found
Phase transitions and the internal noise structure of nonlinear Schr\"odi nger equation solitons
We predict phase-transitions in the quantum noise characteristics of systems
described by the quantum nonlinear Schr\"odinger equation, showing them to be
related to the solitonic field transition at half the fundamental soliton
amplitude. These phase-transitions are robust with respect to Raman noise and
scattering losses. We also describe the rich internal quantum noise structure
of the solitonic fields in the vicinity of the phase-transition. For optical
coherent quantum solitons, this leads to the prediction that eliminating the
peak side-band noise due to the electronic nonlinearity of silica fiber by
spectral filtering leads to the optimal photon-number noise reduction of a
fundamental soliton.Comment: 10 pages, 5 figure
Soliton back-action evading measurement using spectral filtering
We report on a back-action evading (BAE) measurement of the photon number of
fiber optical solitons operating in the quantum regime. We employ a novel
detection scheme based on spectral filtering of colliding optical solitons. The
measurements of the BAE criteria demonstrate significant quantum state
preparation and transfer of the input signal to the signal and probe outputs
exiting the apparatus, displaying the quantum-nondemolition (QND) behavior of
the experiment.Comment: 5 pages, 5 figure
An Exploration of the Occupational Therapy Doctoral Capstone: Perspectives from Capstone Coordinators, Graduates, and Site Mentors
Few studies have investigated entry-level doctoral capstone outcomes regarding how the experience and project relate to employment opportunities. This descriptive study reports various stakeholders’ perspectives regarding the entry-level occupational therapy doctoral (OTD) capstone in relation to employment opportunities and awareness of the profession. Authors disseminated a nationwide survey to doctoral capstone coordinators, entry-level OTD graduates, and capstone site mentors. Ten doctoral capstone coordinators, 68 OTD graduates, and 22 capstone site mentors responded to the survey. Collectively, doctoral capstone coordinators reported that 117 OTD graduates obtained employment in a setting related to the focus of their doctoral capstone and gave examples of graduates employed as entrepreneurs, faculty, program specialists, and supervisors. OTD graduates most often completed their doctoral capstones in community-based settings with projects focusing on program development. Sixty-four percent of the OTD graduates were employed at their doctoral capstone site or at a site similar to where they completed their doctoral capstone. Professional background of capstone site mentors varied, and all mentors who were not occupational therapy professionals reported improved awareness of occupational therapy after mentoring an OTD student. Outcomes of the OTD doctoral capstone are needed to support the efficacy of this experience and project. This study begins to provide such outcomes by reporting findings related to employment and awareness of the profession
Sepsis induces platelet mitochondrial uncoupling and a gradual increase in respiratory capacity that is negatively associated with clinical outcome
On the Culture of Scholarship of Teaching and Learning
This article welcomes you to the first issue of TLCSD. In this brief paper, the members of the Editorial Board introduce you to the key concepts that include the value of evidence-based education in our field, the nature of SoTL research, and the corresponding framework for the submission categories that you will find within TLCSD. Particular emphasis is placed on describing the peer-review process, specifically the need for peer-reviews that provide constructive feedback that facilitates improvements in the manuscripts
Inhibition of the Nuclear Factor-κB Pathway Prevents Beta Cell Failure and Diet Induced Diabetes in Psammomys obesus
BACKGROUND: High doses of anti-inflammatory drugs, such as aspirin and salicylates, improve glucose metabolism in insulin resistant and type 2 diabetic patients. It has also been shown that the glucose lowering effect is related to the unspecific ability of these drugs to inhibit inhibitor kinaseβ (IKKβ). In this study we have investigated the effect of a selective IKKβ-inhibitor on beta cell survival and the prevention of diet induced type 2 diabetes in the gerbil Psammomys obesus (P. obesus). METHODOLOGY/PRINCIPAL FINDINGS: P. obesus were fed a diabetes inducing high energy diet for one month in the absence or presence of the IKKβ-inhibitor. Body mass, blood glucose, HbA(1C), insulin production and pancreatic insulin stores were measured. The effects on beta cell survival were also studied in INS-1 cells and primary islets. The cells were exposed to IL-1β and subsequently reactive oxygen species, insulin release and cell death were measured in the absence or presence of the IKKβ-inhibitor. In primary islets and beta cells, IL-1β induced the production of reactive oxygen species, reduced insulin production and increased beta cell death, which were all reversed by pre-treatment with the IKKβ-inhibitor. In P. obesus the IKKβ-inhibitor prevented the development of hyperglycaemia and hyperinsulinaemia, and maintained pancreatic insulin stores with no effect on body weight. CONCLUSIONS/SIGNIFICANCE: Inhibition of IKKβ activity prevents diet-induced diabetes in P. obesus and inhibits IL-1β induced reactive oxygen species, loss of insulin production and beta cell death in vitro
Nonclassical correlations of photon number and field components in the vacuum state
It is shown that the quantum jumps in the photon number n from zero to one or
more photons induced by backaction evasion quantum nondemolition measurements
of a quadrature component x of the vacuum light field state are strongly
correlated with the quadrature component measurement results. This correlation
corresponds to the operator expectation value which is equal to one
fourth for the vacuum even though the photon number eigenvalue is zero. Quantum
nondemolition measurements of a quadrature component can thus provide
experimental evidence of the nonclassical operator ordering dependence of the
correlations between photon number and field components in the vacuum state.Comment: 13 pages, 3 figures, corrections of omissions in equations (6) and
(25). To be published in Phys. Rev.
Polarimetric dimension and nonregularity of tightly focused light beams
Polarimetric dimension and nonregularity are newly introduced concepts that characterize three-dimensional (3D) polarization states of light. We analyze the spectral polarimetric dimension and the degree of nonregularity associated with two kinds of tightly focused beams: A radially fully polarized Gaussian Schell-model (GSM) beam and a partially polarized beam composed of an incoherent superposition of two orthogonally polarized (coherent) plane-wave modes. We show that for both beams the focal field can exhibit genuine 3D and nonregular character, with even perfect nonregularity encountered for the tightly focused two-mode beam. These features originate from the partial spatial coherence and partial polarization of the incident beams, and in the limit of full coherence and polarization the three-dimensionality and nonregularity of the focal field vanish. We also find that the GSM beam can generate a nanoscale region around the focus where the field is essentially 3D unpolarized. The results demonstrate the rich polarimetric structure of focal fields and may find uses in optical particle manipulation and sensing
IRC+10216's Innermost Envelope -- The eSMA's View
We used the Extended Submillimeter Array (eSMA) in its most extended
configuration to investigate the innermost (within a radius of 290 R* from the
star) circumstellar envelope (CSE) of IRC+10216. We imaged the CSE using HCN
and other molecular lines with a beam size of 0."22 x 0."46, deeply into the
very inner edge (15 R*) of the envelope where the expansion velocity is only 3
km/s. The excitation mechanism of hot HCN and KCl maser lines is discussed. HCN
maser components are spatially resolved for the first time on an astronomical
object. We identified two discrete regions in the envelope: a region with a
radius of . 15 R*, where molecular species have just formed and the gas has
begun to be accelerated (region I) and a shell region (region II) with a radius
of 23 R* and a thickness of 15 R*, whose expansion velocity has reached up to
13 km/s, nearly the terminal velocity of 15 km/s. The SiS line detected
in region I shows a large expansion velocity of 16 km/s due to strong wing
components, indicating that the emission may arise from a shock region in the
innermost envelope. In region II, the P.A. of the most copious mass loss
direction was found to be 120 +/- 10 degrees, which may correspond to the
equatorial direction of the star. Region II contains a torus-like feature.
These two regions may have emerged due to significant differences in the size
distributions of the dust particles in the two regions.Comment: 26 pages, 8 figures, accepted for publication in The Astrophysical
Journal. Please find the pdf at
http://www.submm.caltech.edu/~hs/astroph/0904.0280.pdf and the ps file at
http://www.submm.caltech.edu/~hs/astroph/0904.0280.p
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Intercomparison of in-situ aircraft and satellite aerosol measurements in the stratosphere
Aerosol composition and optical scattering from particles in the lowermost stratosphere (LMS) have been studied by comparing in-situ aerosol samples from the IAGOS-CARIBIC passenger aircraft with vertical profiles of aerosol backscattering obtained from the CALIOP lidar aboard the CALIPSO satellite. Concentrations of the dominating fractions of the stratospheric aerosol, being sulphur and carbon, have been obtained from post-flight analysis of IAGOS-CARIBIC aerosol samples. This information together with literature data on black carbon concentrations were used to calculate the aerosol backscattering which subsequently is compared with measurements by CALIOP. Vertical optical profiles were taken in an altitude range of several kilometres from and above the northern hemispheric extratropical tropopause for the years 2006-2014. We find that the two vastly different measurement platforms yield different aerosol backscattering, especially close to the tropopause where the influence from tropospheric aerosol is strong. The best agreement is found when the LMS is affected by volcanism, i.e., at elevated aerosol loadings. At background conditions, best agreement is obtained some distance (>2 km) above the tropopause in winter and spring, i.e., at likewise elevated aerosol loadings from subsiding aerosol-rich stratospheric air. This is to our knowledge the first time the CALIPSO lidar measurements have been compared to in-situ long-term aerosol measurements. © 2019, The Author(s)
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