688 research outputs found
Ăvaluation prĂ©coce de la vitesse de coordination visuomotrice chez des patients atteints dâun traumatisme craniocĂ©rĂ©bral lĂ©ger
Essai doctoral prĂ©sentĂ© en vue de lâobtention du grade de doctorat en psychologie, option neuropsychologie cliniqueContexte : Lâobjectif de cette Ă©tude est dâexplorer la vitesse de coordination visuomotrice aprĂšs un traumatisme craniocĂ©rĂ©bral lĂ©ger (TCCL) et dâidentifier les prĂ©dicteurs de la performance de celle-ci en phase prĂ©coce de rĂ©cupĂ©ration. MĂ©thode : Un total de 99 patients TCCL et 32 participants en santĂ© a Ă©tĂ© recrutĂ©. Dix-neuf participants avaient subi un TCCL complexe (CT scan positif) et 80 participants Ă©taient atteints dâun TCCL simple (CT scan nĂ©gatif). LâĂąge, le sexe et le niveau de scolaritĂ© ainsi que les performances aux tests de RepĂ©rage de symboles, Codes, Vocabulaire du WAIS-IV ont rĂ©trospectivement Ă©tĂ© recueillis ainsi que des mesures de symptĂŽmes post-commotionnels (Post-Concussion Symptom Scale-Revised) et de dĂ©pression (Beck Depression Inventory II). La vitesse de coordination visuomotrice a Ă©tĂ© mesurĂ©e Ă lâaide du Grooved Pegboard Test. RĂ©sultats: Aucune diffĂ©rence de performance nâa Ă©tĂ© observĂ©e entre les groupes dans la performance obtenue avec la main dominante et la main non dominante (pË .05). LâĂąge, le sexe et la vitesse de traitement de lâinformation (RepĂ©rage de symboles et Codes) Ă©taient des prĂ©dicteurs significatifs de la performance au Grooved Pegboard Test. Pour la main dominante, la sĂ©vĂ©ritĂ© des symptĂŽmes post-commotionnels prĂ©disait Ă©galement la performance. Cependant, la prĂ©sence de symptĂŽmes de dĂ©pression et la rĂ©serve cognitive, Ă©valuĂ©e par le niveau de scolaritĂ© et un test de vocabulaire, nâĂ©taient pas associĂ©es aux performances au Grooved Pegboard Test. Conclusion: Aucune diffĂ©rence de la vitesse de coordination visuomotrice nâa Ă©tĂ© observĂ©e entre le groupe de patients TCCL et les contrĂŽles. Par ailleurs, ĂȘtre un homme, ĂȘtre plus ĂągĂ© et plus lent aux Ă©preuves de vitesse de traitement du WAIS-IV a Ă©tĂ© associĂ© Ă de moins bonnes performances au Grooved Pegboard Test. De surcroit, les symptĂŽmes post-commotionnels semblent interfĂ©rer avec la performance de la main dominante. Enfin, lâĂ©tat dĂ©pressif ou la rĂ©serve cognitive nâont pas Ă©tĂ© associĂ©s Ă la vitesse de la coordination motrice Ă la suite dâun TCCL.
Mots-clés : traumatism
Four year surveillance of central line-associated bloodstream infection (CLABSI) in neonatal intensive care unit (NICU)
Healthcare-associated (HA) bloodstream infections (BSI) secondary top surgical site infections: surveillance program across Quebec hospitals (2007 to 2010)
Is Blood Donation an Opportunity for Hypertension Awareness?
Blood centers serve as a cornerstone of public health by providing potentially lifesaving blood products. Interactions with millions of potential donors provides these centers with a unique means of health education and screening opportunities.https://scholarworks.uvm.edu/comphp_gallery/1081/thumbnail.jp
Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin.
Immunohistochemical detection of macrophage migration inhibitory factor in fetal and adult bovine epididymis: Release by the apocrine secretion mode?
Originally defined as a lymphokine inhibiting the random migration of macrophages, the macrophage migration inhibitory factor (MIF) is an important mediator of the host response to infection. Beyond its function as a classical cytokine, MIF is currently portrayed as a multifunctional protein with growth-regulating properties present in organ systems beyond immune cells. In previous studies, we detected substantial amounts of MIF in the rat epididymis and epididymal spermatozoa, where it appears to play a role during post-testicular sperm maturation and the acquisition of fertilization ability. To explore its presence in other species not yet examined in this respect, we extended the range of studies to the bull. Using a polyclonal antibody raised against MIF purified from bovine eye lenses, we detected MIF in the epithelium of the adult bovine epididymis with the basal cells representing a prominently stained cell type. A distinct accumulation of MIF at the apical cell pole of the epithelial cells and in membranous vesicles localized in the lumen of the epididynnal duct was obvious. In the fetal bovine epididymis, we also detected MIF in the epithelium, whereas MIF accumulation was evident at the apical cell surface and in apical protrusions. By immuno-electron microscopy of the adult bovine epididymis, we localized MIF in apical protrusions of the epithelial cells and in luminal membrane-bound vesicles that were found in close proximity to sperm cells. Although the precise origin of the MIF-containing vesicles remains to be delineated, our morphological observations support the hypothesis that they become detached from the apical surface of the epididymal epithelial cells. Additionally, an association of MIF with the outer dense fibers of luminal spermatozoa was demonstrated. Data obtained in this study suggest MIF release by an apocrine secretion mode in the bovine epididymis. Furthermore, MIF localized in the basal cells of the epithelium and in the connective tissue could be responsible for regulating the migration of macrophages in order to avoid contact of immune cells with spermatozoa that carry a wide range of potent antigens. Copyright (c) 2006 S. Karger AG, Basel
Collagen Meniscal Implantation Outcomes Following Partial and Full Meniscectomies
Meniscal injuries are a common result of trauma to the knee. The main two surgical treatments available are partial meniscectomy or full meniscectomy due to the lack of blood flow in that region. These two treatments cause long-term complications such as pain, lack of mobility, and/or osteoarthritis.
To avoid these complications, researchers have looked at placing collagen meniscal implantations (CMI) into the knee. The collagen implantation is composed of type I collagen from bovine Achilles tendon and was infused with glycosaminoglycans (GAGs) to trigger cellular growth. Patients were grouped into cohorts based on tears in the lateral or medial meniscus that underwent a partial or full meniscectomy. Following the procedure, patients were evaluated based on Tegner scale, Lysholm Score, IKDC, and MRI outcomes. These patients were then reevaluated at two years, five years, and ten years.
The implantation had a 90% survival rate at ten years. CMI has proved to be a practical possibility for patients who have had a partial or full meniscectomy due to the regenerative qualities and reduced deterioration of the knee itself. The research showed that there were significant improvements in quality of life and long-term outcomes. This is a practical option for patients that live an active lifestyle or occupations that require adequate range of motion
Imaging of z~2 QSO host galaxies with the Hubble Space Telescope
We report on deep imaging in 2 filters with the PC2 camera of HST, of five
QSOs at redshift ~2, with a range of optical and radio luminosity. The
observations included a suite of PSF observations which were used to construct
new PSF models, described elsewhere by Dumont et al. The new PSF models were
used to remove the QSO nucleus from the images. We find that the host galaxies
have resolved flux of order 10% of the QSO nuclei, and are generally luminous
and blue, indicating active star-formation. While most have clearly irregular
morphologies, the bulk of the flux can be modelled approximately by an r**1/4
law. However, all host galaxies also have an additional approximately
exponential luminosity profile beyond a radius about 0.8 arcsec, as also seen
in ground-based data with larger telescopes. The QSOs all have a number of
nearby faint blue companions which may be young galaxies at the QSO redshift.
We discuss implications for evolution of the host galaxies, their spheroidal
populations, and central black holes.Comment: 18 pages including 2 tables; to appear in A
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