An exploratory study of teachers\u27 views of knowledge acquisition

This exploratory investigation examined relations between teachers\u27 views of knowledge acquisition and their use of computers in the classroom. A survey instrument that assessed views ranging from objectivism to constructivism is described; and teaching experience, demographic variables, and types of software programs likely to be used are discussed

Protective adaptation of low serum triiodothyronine in patients with chronic renal failure

Protective adaptation of low serum triiodothyronine in patients with chronic renal failure. Low serum triiodothyronine (T3) concentration is frequently found in patients with chronic renal failure (CRF). To test the hypothesis that this may serve to minimize protein catabolism in these patients, we measured nitrogen balance (Nb) in seven CRF and four control subjects in the basal state and when serum T3 concentration was elevated by L-triiodothyronine (LT3) and suppressed by sodium ipodate administration. In the basal state, both the controls and the CRF patients were in positive Nb, 0.02 ± 0.51 and 0.58 ± 0.34 g/day, respectively. During LT3 administration, Nb decreased to -0.80 ± 0.39 g/day in the CRF patients (P < 0.01), but remained positive, 0.22 ± 0.67 g/day, in the controls. There was a significant negative correlation between serum T3 concentration and Nb in the CRF patients (r = -0.63, P < 0.005), but not in the controls. Furthermore, urea nitrogen generation rate, calculated from urea kinetics, increased from a baseline of 4.6 ± 0.55 to 6.0 ± 0.50 mg/min during LT3 administration in the CRF patients (P < 0.01). Sodium ipodate, which significantly lowered serum T3 concentrations, had little effect on nitrogen metabolism in the controls and the CRF patients. These data support the concept that low serum T3 concentrations may confer a protective effect on CRF patients regarding protein-nitrogen conservation and provide a rationale for not correcting such deficiency

Orchard Day, August 18, 1955; Results of Fruit Research

Storing peaches / Donald Comin -- Trends in storages / Donald Comin -- Grape varieties ; Grape soil management and fertilization ; Nitrogen fertilizers for apple trees / J. M. Beattie -- Colorset on Golden Delicious and Grimes ; Planting distance influence on yield of apples ; Harvest dates for apples ; Summer varieties of apples ; Pre-harvest spraying for Baldwin / C. W. Ellenwood -- Peach investigations ; The blueberry planting ; Strawberry studies ; Plum varieties and culture ; Grape weed control studies / R. G. Hill, Jr. -- Semi-dwarf apple trees in Ohio / Freeman S. Howlett and T. E. Fowler -- The Franklin Apple / Freeman S. Howlett and C. W. Ellenwood -- Status of intermediate (trunk-forming) stocks for the apple ; Pruning the newly planted apple tree ; Status of the pear industry in Ohio / Freeman S. Howlett -- Pear variety collection indicates several deserve limited trial / Freeman S. Howlett and C. W. Ellenwoo

RELEASE (REdressing Long-tErm Antidepressant uSE): protocol for a 3-arm pragmatic cluster randomised controlled trial effectiveness-implementation hybrid type-1 in general practice

BACKGROUND: Many people experience withdrawal symptoms when they attempt to stop antidepressants. Withdrawal symptoms are readily misconstrued for relapse or ongoing need for medication, contributing to long-term use (> 12 months). Long-term antidepressant use is increasing internationally yet is not recommended for most people. Long-term use is associated with adverse effects including weight gain, sexual dysfunction, lethargy, emotional numbing and increased risk of falls and fractures. This study aims to determine the effectiveness of two multi-strategy interventions (RELEASE and RELEASE+) in supporting the safe cessation of long-term antidepressants, estimate cost-effectiveness, and evaluate implementation strategies. METHODS: DESIGN: 3-arm pragmatic cluster randomised controlled trial effectiveness-implementation hybrid type-1. SETTING: primary care general practices in southeast Queensland, Australia. POPULATION: adults 18 years or older taking antidepressants for longer than 1 year. Practices will be randomised on a 1.5:1:1 ratio of Usual care:RELEASE:RELEASE+. INTERVENTION: RELEASE for patients includes evidence-based information and resources and an invitation to medication review; RELEASE for GPs includes education, training and printable resources via practice management software. RELEASE+ includes additional internet support for patients and prescribing support including audit and feedback for GPs. OUTCOME MEASURES: the primary outcome is antidepressant use at 12 months self-reported by patients. Cessation is defined as 0 mg antidepressant maintained for at least 2 weeks. SECONDARY OUTCOMES: at 6 and 12 months are health-related quality of life, antidepressant side effects, well-being, withdrawal symptoms, emotional numbing, beliefs about antidepressants, depressive symptoms, and anxiety symptoms; and at 12 months 75% reduction in antidepressant dose; aggregated practice level antidepressant prescribing, and health service utilisation for costs. SAMPLE SIZE: 653 patients from 28 practices. A concurrent evaluation of implementation will be through mixed methods including interviews with up to 40 patients and primary care general practitioners, brief e-surveys, and study administrative data to assess implementation outcomes (adoption and fidelity). DISCUSSION: The RELEASE study will develop new knowledge applicable internationally on the effectiveness, cost-effectiveness, and implementation of two multi-strategy interventions in supporting the safe cessation of long-term antidepressants to improve primary health care and outcomes for patients. TRIAL REGISTRATION: ANZCTR, ACTRN12622001379707p. Registered on 27 October 2022

Orienting student veterans to the library: Piloting a new model of library orientation

This poster was presented at ALA 2018, the annual conference of the American Library Association.Student veterans and military service members are a unique population on college and university campuses. They are non-traditional students and often transfer students who can feel isolated among a large population of traditional students. As such, student veterans and service members are often better served by a tailored orientation approach. But getting student veterans and service members to attend a special library orientation can be difficult. Librarians and leaders of the campus veterans center were awarded an IMLS Sparks! grant aimed at developing a new model of library orientation for veterans. This new model builds on these students’ prior knowledge by adapting the model used by the military to orient service members to new duty stations. This orientation model goes beyond a presentation or resource table to provide students with an orientation tailored to their needs and to facilitate exploration of the physical library space. This model also accommodates busy schedules and competing responsibilities by enabling student veterans and service members to complete their orientation on their own time

The inhibition of \u3cem\u3eStaphylococcus epidermidis\u3c/em\u3e biofilm formation by vancomycinmodified titanium alloy and implications for the treatment of periprosthetic infection

Peri-prosthetic infections are notoriously difficult to treat as the biomaterial implant is ideal for bacterial adhesion and biofilm formation, resulting in decreased antibiotic sensitivity. Previously, we reported that vancomycin covalently attached to a Ti alloy surface (Vanc-Ti) could prevent bacterial colonization. Herein we examine the effect of this Vanc-Ti surface on Staphylococci epidermidis, a Gram-positive organism prevalent in orthopaedic infections. By direct colony counting and fluorescent visualization of live bacteria, S. epidermidis colonization was significantly inhibited on Vanc-Ti implants. In contrast, the gram-negative organism Escherichia coli readily colonized the Vanc-Ti rod, suggesting retention of antibiotic specificity. By histochemical and SEM analysis, Vanc-Ti prevented S. epidermidis biofilm formation, even in the presence of serum. Furthermore, when challenged multiple times with S. epidermidis, Vanc-Ti rods resisted bacterial colonization. Finally, when S. epidermidis was continuously cultured in the presence of Vanc-Ti, the bacteria maintained a Vanc sensitivity equivalent to the parent strain. These findings indicate that antibiotic derivatization of implants can result in a surface that can resist bacterial colonization. This technology holds great promise for the prevention and treatment of periprosthetic infections

Computer Microvision for Microelectromechanical Systems

Contains table of contents for Section 3 and reports on five research projects.Charles S. Draper Laboratory Contract DL-H-496015Defense Advanced Research Project Agency Grant F30602-97-2-0106W.M. Keck Foundation Career Development ProfessorshipAlfred P. Sloan Foundation Instrumentation Gran