Cox regression models analyzing the association between education level and overall 5-year mortality after esophagectomy for cancer, stratified by patient and tumor characteristics, using multiple imputations for missing values.

<p>Values are expressed as hazard ratios (HRs) and 95% confidence intervals (CIs).*</p><p>* All values were adjusted for age (≤61, 62–70, or >70 years), sex (male or female), comorbidity (0, 1, or >1), tumor stage (0-I, II, III, or IV), and tumor histology (squamous cell carcinoma or adenocarcinoma).</p><p>Cox regression models analyzing the association between education level and overall 5-year mortality after esophagectomy for cancer, stratified by patient and tumor characteristics, using multiple imputations for missing values.</p

Cox regression models analyzing trends over time in the association between education level and overall 5-year mortality after esophagectomy for cancer, with the highly educated group operated between 2003 and 2010 as reference, using multiple imputation for missing values.

<p>Values are expressed as hazard ratios (HRs) and 95% confidence intervals (CI).*</p><p>* All values were adjusted for age (≤61, 62–70, or >70 years), sex (male or female), comorbidity (0, 1, or >1), tumor stage (0-I, II, III, or IV), and tumor histology (squamous cell carcinoma or adenocarcinoma).</p><p>Cox regression models analyzing trends over time in the association between education level and overall 5-year mortality after esophagectomy for cancer, with the highly educated group operated between 2003 and 2010 as reference, using multiple imputation for missing values.</p

Kaplan Meier Curve of survival after esophagectomy for cancer, categorized by education level.

<p>Kaplan Meier Curve of survival after esophagectomy for cancer, categorized by education level.</p

Cox regression models analyzing the association between education level and mortality after esophagectomy for cancer, using multiple imputation for missing values.

<p>Values are expressed as hazard ratios (HRs) and 95% confidence intervals (CIs).</p><p>* Adjusted for age (≤61, 62–70, or >70 years), sex (male or female), comorbidity (0, 1, or >1), tumor stage (0-I, II, III, or IV), and tumor histology (squamous cell carcinoma or adenocarcinoma).</p><p>^<i>#</i> Conditional mortality: excluding first 90 days after surgery.</p><p>Cox regression models analyzing the association between education level and mortality after esophagectomy for cancer, using multiple imputation for missing values.</p

Patient and tumor characteristics and mortality after esophagectomy for cancer (n = 1822), categorized by education level.

<p>* Conditional: excluding first 90 days after surgery</p><p>Patient and tumor characteristics and mortality after esophagectomy for cancer (n = 1822), categorized by education level.</p

Additional file 2: Table S2. of Angiotensin II receptor blockers and risk of acute pancreatitis - a population based case–control study in Sweden

Exposure to angiotensin receptor blockers (ARB) and risk of different types of acute pancreatitis, estimated by odds ratios (OR) with 95% confidence intervals (CI), in a nested case–control study in Sweden. Table S3. Exposure to angiotensin receptor blockers (ARB) stratified among users of cardiovascular drugs, estimated by odds ratios (OR) with 95% confidence intervals (CI). (DOCX 20 kb

Additional file 1: Table S1A. of Angiotensin II receptor blockers and risk of acute pancreatitis - a population based case–control study in Sweden

Type of Angiotensin Receptor Blockers in relation to acute pancreatitis status. Table S1B. Duration of Angiotensin Receptor Blockers usage in relation to acute pancreatitis status. Table S1C. Estimated risk of acute pancreatitis in relation to duration of ARB. (DOCX 19 kb

Kaplan Meier curve showing survival time in days by exposure group.

<p>Kaplan Meier curve showing survival time in days by exposure group.</p

Systematic underreporting of the population-based incidence of pancreatic and biliary tract cancers

<div><p></p><p><i>Background.</i> Incidence rates of cancers of the pancreas and biliary tract, typically derived from cancer registers, have been reported to be decreasing. This study tested whether pancreatic and biliary tract cancers are underreported in the Swedish Cancer Register (CR). <i>Methods.</i> The concordance of pancreatic and biliary tract cancer diagnoses in 1990–2009 between CR and the Swedish Patient Register (PR) were evaluated through record linkage. To further assess the completeness of these cancer diagnoses in both CR and PR, record linkage was also made to the Swedish Causes of Death Register (DR). <i>Results.</i> A total of 31 067 cases of pancreatic cancer and 14 273 cases of biliary tract cancer were identified in CR or PR. Altogether, 44% of the pancreatic cancers and 44% of the biliary tract cancers were registered in PR only, and not in CR. The concordance between CR and PR declined from 63% in the years 1990–1994 to 44% in 2005–2009 for pancreatic cancer. The corresponding figures for biliary tract cancer were 60% and 37%. This decline in concordance was also observed with increasing age, e.g. the concordance between CR and PR for pancreatic cancer declined from 62% in patients < 60 years to 36% among patients ≥ 80 years. The corresponding figures for biliary tract cancer were 52% and 38%. <i>Conclusion.</i> There is an overwhelming underreporting of pancreatic and biliary tract cancers within the Swedish Cancer Register, which has increased during recent years. The reported decreasing incidence rates for pancreatic and biliary tract cancers might therefore be incorrect.</p></div

Additional file 1 of Aspirin or statin use in relation to survival after surgery for esophageal cancer: a population-based cohort study

Additional file 1