5,491 research outputs found

    Life After Being a Pathology Department Chair II: Lessons Learned.

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    The 2016 Association of Pathology Chairs annual meeting featured a discussion group of Association of Pathology Chairs senior fellows (former chairs of academic departments of pathology who have remained active in Association of Pathology Chairs) that focused on how they decided to transition from the chair, how they prepared for such transition, and what they did after the transition. At the 2017 annual meeting, the senior fellows (encompassing 481 years of chair service) discussed lessons they learned from service as chair. These lessons included preparation for the chairship, what they would have done differently as chair, critical factors for success as chair, factors associated with failures, stress reduction techniques for themselves and for their faculty and staff, mechanisms for dealing with and avoiding problems, and the satisfaction they derived from their service as chair. It is reasonable to assume that these lessons may be representative of those learned by chairs of other specialties as well as by higher-level academic administrators such as deans, vice presidents, and chief executive officers. Although the environment for serving as a department chair has been changing dramatically, many of the lessons learned by former chairs are still valuable for current chairs of any length of tenure

    Lithopanspermia in Star Forming Clusters

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    This paper considers the lithopanspermia hypothesis in star forming groups and clusters, where the chances of biological material spreading from one solar system to another is greatly enhanced (relative to the field) due to the close proximity of the systems and lower relative velocities. These effects more than compensate for the reduced time spent in such crowded environments. This paper uses 300,000 Monte Carlo scattering calculations to determine the cross sections for rocks to be captured by binaries and provides fitting formulae for other applications. We assess the odds of transfer as a function of the ejection speed and number of members in the birth aggregate. The odds of any given ejected meteroid being recaptured by another solar system are relatively low. Because the number of ejected rocks per system can be large, virtually all solar systems are likely to share rocky ejecta with all of the other solar systems in their birth cluster. The number of ejected rocks that carry living microorganisms is much smaller and less certain, but we estimate that several million rocks can be ejected from a biologically active solar system. For typical birth environments, the capture of life bearing rocks is expected to occur 10 -- 16,000 times per cluster (under favorable conditions), depending on the ejection speeds. Only a small fraction of the captured rocks impact the surfaces of terrestrial planets, so that only a few lithopanspermia events are expected (per cluster).Comment: 27 pages including 5 figures; accepted to Astrobiolog

    The Evolution of the Water Distribution in a Viscous Protoplanetary Disk

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    (Abridged) Astronomical observations have shown that protoplanetary disks are dynamic objects through which mass is transported and accreted by the central star. Age dating of meteorite constituents shows that their creation, evolution, and accumulation occupied several Myr, and over this time disk properties would evolve significantly. Moreover, on this timescale, solid particles decouple from the gas in the disk and their evolution follows a different path. Here we present a model which tracks how the distribution of water changes in an evolving disk as the water-bearing species experience condensation, accretion, transport, collisional destruction, and vaporization. Because solids are transported in a disk at different rates depending on their sizes, the motions will lead to water being concentrated in some regions of a disk and depleted in others. These enhancements and depletions are consistent with the conditions needed to explain some aspects of the chemistry of chondritic meteorites and formation of giant planets. The levels of concentration and depletion, as well as their locations, depend strongly on the combined effects of the gaseous disk evolution, the formation of rapidly migrating rubble, and the growth of immobile planetesimals. We present examples of evolution under a range of plausible assumptions and demonstrate how the chemical evolution of the inner region of a protoplanetary disk is intimately connected to the physical processes which occur in the outer regions.Comment: 45 pages, 7 figures, revised for publication in Icaru

    Spike Onset Dynamics and Response Speed in Neuronal Populations

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    Recent studies of cortical neurons driven by fluctuating currents revealed cutoff frequencies for action potential encoding of several hundred Hz. Theoretical studies of biophysical neuron models have predicted a much lower cutoff frequency of the order of average firing rate or the inverse membrane time constant. The biophysical origin of the observed high cutoff frequencies is thus not well understood. Here we introduce a neuron model with dynamical action potential generation, in which the linear response can be analytically calculated for uncorrelated synaptic noise. We find that the cutoff frequencies increase to very large values when the time scale of action potential initiation becomes short

    Reduced-order modeling and dynamics of nonlinear acoustic waves in a combustion chamber

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    For understanding the fundamental properties of unsteady motions in combustion chambers, and for applications of active feedback control, reduced-order models occupy a uniquely important position. A framework exists for transforming the representation of general behavior by a set of infinite-dimensional partial differential equations to a finite set of nonlinear second-order ordinary differential equations in time. The procedure rests on an expansion of the pressure and velocity fields in modal or basis functions, followed by spatial averaging to give the set of second-order equations in time. Nonlinear gasdynamics is accounted for explicitly, but all other contributing processes require modeling. Reduced-order models of the global behavior of the chamber dynamics, most importantly of the pressure, are obtained simply by truncating the modal expansion to the desired number of terms. Central to the procedures is a criterion for deciding how many modes must be retained to give accurate results. Addressing that problem is the principal purpose of this paper. Our analysis shows that, in case of longitudinal modes, a first mode instability problem requires a minimum of four modes in the modal truncation whereas, for a second mode instability, one needs to retain at least the first eight modes. A second important problem concerns the conditions under which a linearly stable system becomes unstable to sufficiently large disturbances. Previous work has given a partial answer, suggesting that nonlinear gasdynamics alone cannot produce pulsed or 'triggered' true nonlinear instabilities; that suggestion is now theoretically established. Also, a certain form of the nonlinear energy addition by combustion processes is known to lead to stable limit cycles in a linearly stable system. A second form of nonlinear combustion dynamics with a new velocity coupling function that naturally displays a threshold character is shown here also to produce triggered limit cycle behavior
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