Flood modelling with hydraTE: 2+1-dimensional smoothed-particle hydrodynamics

We present HydraTE, our own implementation of the smoothed-particle hydrodynamics technique for shallow water that uses the adaptive size of the smoothing kernel as a proxy for the local water depth. We derive the equa- tions of motion for this approach from the Lagrangian before demonstrating that we can model the depth of water in a trough, implement vertical walls, recover the correct acceleration and terminal velocity for water flowing down a slope and obtain a stable hydraulic jump with the correct jump condition. We demonstrate that HydraTE performs well on two of the UK Environ- ment Agency flood modelling benchmark tests. Benchmark EA3 involves flow down an incline into a double dip depression and studies the amount of water that reaches the second dip. Our results are in agreement with those of the other codes that have attempted this test. Benchmark EA6 is a dam break into a horizontal channel containing a building. HydraTE again pro- duces results that are in good agreement with the other methods and the experimetal validation data except where the vertical velocity structure of the flow is expected to be multi-valued, such as the hydralic jump where the precise location is not recovered even though the pre- and post- jump water heights are. We conclude that HydraTE is suitable for a wide range of flood modelling problems as it preforms at least as well as the best available commercial alternatives for the problems we have tested

Dynamical Realization of Macroscopic Superposition States of Cold Bosons in a Tilted Double Well

We present exact expressions for the quantum sloshing of Bose-Einstein condensates in a tilted two-well potential. Tunneling is suppressed by a small potential difference between wells, or tilt. However, tunneling resonances occur for critical values of the tilt when the barrier is high. At resonance, tunneling times on the order of 10-100 ms are possible. Furthermore, such tilted resonances lead to a dynamical scheme for creating few-body NOON-like macroscopic superposition states which are protected by the many body wavefunction against potential fluctuations.Comment: 6 pages, 5 figures, final version, only minor changes from previous arXiv versio

The orientation of galaxy dark matter haloes around cosmic voids

Using the Millennium N-body Simulation we explore how the shape and angular momentum of galaxy dark matter haloes surrounding the largest cosmological voids are oriented. We find that the major and intermediate axes of the haloes tend to lie parallel to the surface of the voids, whereas the minor axis points preferentially in the radial direction. We have quantified the strength of these alignments at different radial distances from the void centres. The effect of these orientations is still detected at distances as large as 2.2 Rvoid from the void centre. Taking a subsample of haloes expected to contain disc-dominated galaxies at their centres we detect, at the 99.9 per cent confidence level, a signal that the angular momentum of those haloes tends to lie parallel to the surface of the voids. Contrary to the alignments of the inertia axes, this signal is only detected in shells at the void surface (1 < R < 1.07 Rvoid) and disappears at larger distances. This signal, together with the similar alignment observed using real spiral galaxies, strongly supports the prediction of the Tidal Torque theory that both dark matter haloes and baryonic matter have acquired, conjointly, their angular momentum before the moment of turnaround

Fixation of virgin lunar surface soil

Two systems are shown to be suitable for fixing loose particulate soils with a polymer film, without visually detectable disturbance of the soil particle spatial relationships. A two-component system is described, which uses a gas monomer condensible at the soil temperature and a gas phase catalyst acting to polymerize the monomer. A one-component system using a monomer which polymerizes spontaneously on and within the top few millimeters of the soil is also considered. The two-component system employs a simpler apparatus, but it operates over a narrower temperature range (approximately -40 to -10 C). Other two-component systems were identified which may operate at soil temperatures as high as +100 C, at relatively narrow temperature ranges of approximately 30 C. The one-component system was demonstrated to operate successfully with initial soil temperatures from -70 C or lower to +150 C

Consanguinity and rare mutations outside of MCCC genes underlie nonspecific phenotypes of MCCD.

Purpose3-Methylcrotonyl-CoA carboxylase deficiency (MCCD) is an autosomal recessive disorder of leucine catabolism that has a highly variable clinical phenotype, ranging from acute metabolic acidosis to nonspecific symptoms such as developmental delay, failure to thrive, hemiparesis, muscular hypotonia, and multiple sclerosis. Implementation of newborn screening for MCCD has resulted in broadening the range of phenotypic expression to include asymptomatic adults. The purpose of this study was to identify factors underlying the varying phenotypes of MCCD.MethodsWe performed exome sequencing on DNA from 33 cases and 108 healthy controls. We examined these data for associations between either MCC mutational status, genetic ancestry, or consanguinity and the absence or presence/specificity of clinical symptoms in MCCD cases.ResultsWe determined that individuals with nonspecific clinical phenotypes are highly inbred compared with cases that are asymptomatic and healthy controls. For 5 of these 10 individuals, we discovered a homozygous damaging mutation in a disease gene that is likely to underlie their nonspecific clinical phenotypes previously attributed to MCCD.ConclusionOur study shows that nonspecific phenotypes attributed to MCCD are associated with consanguinity and are likely not due to mutations in the MCC enzyme but result from rare homozygous mutations in other disease genes.Genet Med 17 8, 660-667