FoMO, but not self-compassion, moderates the link between social media use and anxiety in adolescence

Objective Social media use is ubiquitous during adolescence, and emerging research suggests an association with anxiety symptoms in some individuals. Two psychological constructs which may moderate this relationship are Fear of Missing Out (FoMO) and self-compassion. Higher FoMO tendencies may exacerbate the link between social media use and anxiety symptoms through greater fixation on social comparison, whereas higher self-compassion may weaken this link. The purpose of this study was to examine whether FoMO and self-compassion independently moderate the relationship between social media use and anxiety symptoms in adolescents. Method Participants included 951 adolescents (Mage = 13.69, SD = 0.72; 54% male). Online questionnaires assessed frequency of social media use, anxiety symptoms, FoMO, and self-compassion. Results FoMO moderated the relationship between social media use and anxiety, ΔR2 = .022, ΔF(1,945) = 26.26, p < .001. Increased social media use was associated with increased anxiety symptoms in adolescents high in FoMO and reduced anxiety for adolescents low in FoMO. Self-compassion was not a significant moderator. Conclusion These findings have implications for social media use, public guidelines and clinical practice and support adoption of a discerning approach to adolescent’s social media use

Gender based adolescent self-compassion profiles and the mediating role of nonattachment on psychological well-being

Emerging research has shown that boys and girls may relate to compassionate and uncompassionate components of self-compassion differently and have distinct gender based self-compassion profiles. This study extended upon recent research by investigating gender based adolescent self-compassion profiles and their relationship with psychological well-being and the role of nonattachment in the link between self-compassion and well-being. A large cross-sectional sample of Australian Year 10 high school students (N = 1,944, Mage = 15.65 years, SDage = 0.43; 50% girls) completed measures of self-compassion, nonattachment, and well-being. Latent profile analysis identified distinct self-compassion profiles based on gender. Four profiles labelled ‘Low Self-Relating’, ‘Moderate Self-Relating’, ‘Compassionate’, and ‘Uncompassionate’ emerged for girls. Three profiles emerged for boys labelled ‘Low Self-Relating’, ‘Moderate Self-Relating, and ‘Compassionate’. ‘Low’ and ‘Moderate Self-Relating’ profiles involved low and moderate levels of both compassionate and uncompassionate self-relating. ‘Compassionate’ profiles involved high levels of compassionate and low levels of uncompassionate self-relating, and ‘Uncompassionate’ profiles involved the opposite. For both genders, ‘Compassionate’ profiles were associated with the highest psychological well-being and nonattachment and ‘Uncompassionate’ profiles with the lowest of both. ‘Low’ and ‘Moderate Self-Relating’ profiles showed no difference in psychological well-being or nonattachment. Mediation analysis indicated that nonattachment partially mediated the relationship between self-compassion profile and psychological well-being. These findings support recent research that illustrates adolescents relate to the components of self-compassion differently both between and within genders. It also highlights the crucial role nonattachment plays in the relationship between self-compassion and psychological well-being in adolescents

Sleep disturbance mediates the link between both self-compassion and self-criticism and psychological distress during prolonged periods of stress

Poor sleep and subsequent decline in mental health often occur during times of prolonged stress, such as a pandemic. Self-compassion is linked with improved sleep and better mental health, while self-criticism is linked with poorer sleep and psychological distress. Given there is little evidence of the interrelationships of these constructs, we examined whether higher self-compassion or lower levels of self-criticism can reduce psychological distress directly and indirectly via sleep during times of prolonged stress. Structural equation modelling was used to analyse two samples (N = 722, Study 1, and N = 622, Replication Study) of university students during different stages of the pandemic. An aggregate psychological distress construct was calculated using depression, anxiety and stress measures. We created models that showed insomnia symptoms mediated the relationship between self-compassion/self-criticism and psychological distress. Sleep partially mediated both relationships, and this was the strongest effect in both samples. This suggests that improving self-compassion and reducing self-criticism will improve sleep, leading to reduced psychological distress. As our findings are robust and held at two time points, future research should investigate broader demographics and differing stress responses

Letting go, creating meaning : The role of acceptance and commitment therapy in helping people confront existential concerns and lead a vital life

We all must confront existential crises such as sickness, death of loved ones, loss of job, mistreatment from others, and relationship breakdown. These crises can shatter our sense of meaning. How can we face that moment with honesty and courage, embrace the distress, and create new meaning? This chapter provides a theory of how language and self-awareness can lead us into existential crisis and loss of meaning. It then provides an evidence-based account of how the DNA-V model of Acceptance and Commitment Therapy (ACT) can help people to answer “Yes” to Camus’ most important philosophical question, “Is life worth living?”. ACT can help people recreate coherence after a coherence-shattering event, overcome alienation from the body, overcome inertia, overcome a sense of self that is self-destroying or feels “empty,” and bridge the gulf between self and others and create genuine connection

The Compassion Balance: Understanding the Interrelation of Self- and Other-Compassion for Optimal Well-being

Objectives: This study examined the role of self-other harmony in the relations between self-compassion, other-compassion, and well-being. Past research has shown self- and other-compassion to be positively related. But we hypothesised that self-compassion can be perceived as incompatible with other-compassion, and that self-compassion and other-compassion might be uncorrelated or negatively correlated in daily life for some individuals. We termed this pattern lack of self-other harmony in compassion and hypothesised that it would undermine the benefits of compassion. Method: Using an experience sampling method in patients (n=154) with a variety of diagnoses, we measured self-compassion, other-compassion, life-satisfaction, mood, and contextual variables six times per day for 42 time points. Results: For most participants, self-compassion was positively associated with other-compassion. However, there was substantial heterogeneity in this effect. The degree of self-other harmony moderated the link between compassion directed towards self or other and well-being. Higher levels of compassion were associated with higher levels of well-being, but only for those who experienced the harmony. When the two forms of compassion were not in harmony, levels of self/other-compassion were largely unrelated to well-being. Conclusions: The findings emphasise the importance of personalised compassion interventions rather than a one-size-fits-all approach. Increasing self-compassion or other-compassion is likely to improve well-being for most people. However, for a minority lacking the self-other harmony, it may be necessary to assess their interpretation of self- and other-compassion, then work with them to promote the compassion balance optimal for their well-being

The role of insight, social rank, mindfulness and self-compassion in depression following first episode psychosis

Gaining awareness of psychosis (i.e., insight) is linked to depression, particularly in the post-acute phase of psychosis. Informed by social rank theory, we examined whether the insight–depression relationship is explained by reduced social rank related to psychosis and whether self-compassion (including uncompassionate self-responding [UCS] and compassionate self-responding [CSR]) and mindfulness buffered the relationship between social rank and depression in individuals with first episode psychosis during the post-acute phase. Participants were 145 young people (Mage = 20.81; female = 66) with first episode psychosis approaching discharge from an early psychosis intervention centre. Questionnaires and interviews assessed insight, depressive symptoms, perceived social rank, self-compassion, mindfulness and illness severity. Results showed that insight was not significantly associated to depression and thus no mediation analysis was conducted. However, lower perceived social rank was related to higher depression, and this relationship was moderated by self-compassion and, more specifically, UCS. Mindfulness was related to depression but had no moderating effect on social rank and depression. Results supported previous findings that depressive symptoms are common during the post-acute phase. The role of insight in depression for this sample is unclear and may be less important during the post-acute phase than previously considered. Supporting social rank theory, the results suggest that low perceived social rank contributes to depression, and reducing UCS may ameliorate this effect. UCS, social rank and possibly mindfulness may be valuable intervention targets for depression intervention and prevention efforts in the recovery of psychosis

Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair

Canonical roles for macrophages in mediating the fibrotic response after a heart attack include extracellular matrix turnover and activation of cardiac fibroblasts to initiate collagen deposition. Here we reveal that macrophages directly contribute collagen to the forming post-injury scar. Unbiased transcriptomics shows an upregulation of collagens in both zebrafish and mouse macrophages following heart injury. Adoptive transfer of macrophages, from either collagen-tagged zebrafish or adult mouse GFPtpz-collagen donors, enhances scar formation via cell autonomous production of collagen. In zebrafish, the majority of tagged collagen localises proximal to the injury, within the overlying epicardial region, suggesting a possible distinction between macrophage-deposited collagen and that predominantly laid-down by myofibroblasts. Macrophage-specific targeting of col4a3bpa and cognate col4a1 in zebrafish significantly reduces scarring in cryoinjured hosts. Our findings contrast with the current model of scarring, whereby collagen deposition is exclusively attributed to myofibroblasts, and implicate macrophages as direct contributors to fibrosis during heart repair

Serotype Distribution and Drug Resistance in Streptococcus pneumoniae, Palestinian Territories

To determine antimicrobial drug resistance of Streptococcus pneumoniae serotypes, we analyzed isolates from blood cultures of sick children residing in the West Bank before initiation of pneumococcal vaccination. Of 120 serotypes isolated, 50.8%, 73.3%, and 80.8% of the bacteremia cases could have been prevented by pneumococcal conjugate vaccines. Serotype 14 was the most drug-resistant serotype isolated

A pilot study using Tissue Velocity Ultrasound Imaging (TVI) to assess muscle activity pattern in patients with chronic trapezius myalgia

<p>Abstract</p> <p>Background</p> <p>Different research techniques indicate alterations in muscle tissue and in neuromuscular control of aching muscles in patients with chronic localized pain. Ultrasound can be used for analysis of muscle tissue dynamics in clinical practice.</p> <p>Aim</p> <p>This study introduces a new muscle tissue sensitive ultrasound technique in order to provide a new methodology for providing a description of local muscle changes. This method is applied to investigate trapezius muscle tissue response – especially with respect to specific regional deformation and deformation rates – during concentric shoulder elevation in patients with chronic trapezius myalgia and healthy controls before and after pain provocation.</p> <p>Methods</p> <p>Patients with trapezius myalgia and healthy controls were analyzed using an ultrasound system equipped with tissue velocity imaging (TVI). The patients performed a standardized 3-cm concentric shoulder elevation before and after pain provocation/exercise at a standardized elevation tempo (30 bpm). A standardized region of interest (ROI), an ellipsis with a size that captures the upper and lower fascia of the trapezius muscle (4 cm width) at rest, was placed in the first frame of the loop registration of the elevation. The ROI was re-anchored frame by frame following the same anatomical landmark in the basal fascia during all frames of the concentric phase. In cardiac measurement, tissue velocities are measured in the axial projection towards and against the probe where red colour represents shortening and red lengthening. In the case of measuring the trapezius muscle, tissue deformation measurements are made orthogonally, thus, indirectly. Based on the assumption of muscle volume incompressibility, blue represents tissue contraction and red relaxation. Within the ROI, two variables were calculated as a function of time: <it>deformation </it>and <it>deformation rate</it>. Hereafter, max, mean, and quadratic mean values (RMS) of each variable were calculated and compared before and after pain provocation/exercise.</p> <p>Results</p> <p>This new methodology seems valuable when looking at local muscle changes and studying the mechanism behind chronic muscle pain. The univariate analyses indicate that patients with chronic trapezius myalgia after pain provocation due to exercise at group level showed decreased strain and unchanged strain rate while healthy controls had unchanged strain and increased strain rate. However, the multivariate analysis indicates that most patients showed lower levels according to both strain and strain rate after exercise compared to most controls.</p> <p>Conclusion</p> <p>Tissue velocity imaging can help describe musculoskeletal tissue activity and dynamics in patients with chronic pain conditions. An altered muscle tissue dynamic after pain provocation/exercise among the majority of trapezius myalgia patients compared with the healthy controls was found.</p

Social disparities in exposures to bisphenol A and polyfluoroalkyl chemicals: a cross-sectional study within NHANES 2003-2006

<p>Abstract</p> <p>Background</p> <p>Bisphenol A (BPA) and polyfluoroalkyl chemicals (PFCs) are suspected endocrine disrupting compounds known to be ubiquitous in people's bodies. Population disparities in exposure to these chemicals have not been fully characterized.</p> <p>Methods</p> <p>We analyzed data from the 2003-2006 National Health and Nutrition Examination Survey. Using multivariable linear regression we examined the association between urinary concentrations of BPA, serum concentrations of four PFCs, and multiple measures of socioeconomic position (SEP): family income, education, occupation, and food security. We also examined associations with race/ethnicity.</p> <p>Results</p> <p>All four PFCs were positively associated with family income, whereas BPA was inversely associated with family income. BPA concentrations were higher in people who reported very low food security and received emergency food assistance than in those who did not. This association was particularly strong in children: 6-11 year-olds whose families received emergency food had BPA levels 54% higher (95% CI, 13 to 112%) than children of families who did not. For BPA and PFCs we saw smaller and less consistent associations with education and occupation. Mexican Americans had the lowest concentrations of any racial/ethnic group of both types of chemicals; for PFCs, Mexican Americans not born in the U.S. had much lower levels than those born in the U.S.</p> <p>Conclusions</p> <p>People with lower incomes had higher body burdens of BPA; the reverse was true for PFCs. Family income with adjustment for family size was the strongest predictor of chemical concentrations among the different measures of SEP we studied. Income, education, occupation, and food security appear to capture different aspects of SEP that may be related to exposure to BPA and PFCs and are not necessarily interchangeable as measures of SEP in environmental epidemiology studies. Differences by race/ethnicity were independent of SEP.</p