536 research outputs found
Project Managers\u27 Influence Tactics and Authority: A Comparison Across Project Structures
Information Systems (IS) implementation success has been a concern of both researchers and practitioners ever since firms have started to use computer to process their business data. Over the years, researchers have studied several aspects of IS implementation, be it measuring success or developing and testing models that explain IS project success or failure. However, up to now, very little of the IS implementation research has focused on the role played by the project leader. This paper presents the results of a study of 139 IS project managers. The study examined both the tactics adopted by these project managers to influence people, and their level of decision authority
Tuning of Kilopixel Transition Edge Sensor Bolometer Arrays with a Digital Frequency Multiplexed Readout System
A digital frequency multiplexing (DfMUX) system has been developed and used
to tune large arrays of transition edge sensor (TES) bolometers read out with
SQUID arrays for mm-wavelength cosmology telescopes. The DfMUX system
multiplexes the input bias voltages and output currents for several bolometers
on a single set of cryogenic wires. Multiplexing reduces the heat load on the
camera's sub-Kelvin cryogenic detector stage. In this paper we describe the
algorithms and software used to set up and optimize the operation of the
bolometric camera. The algorithms are implemented on soft processors embedded
within FPGA devices operating on each backend readout board. The result is a
fully parallelized implementation for which the setup time is independent of
the array size.Comment: 5 pages, 4 figure
BetaHPV E6 and E7 colocalize with NuMa in dividing keratinocytes
Human papillomaviruses (HPVs) of genus betapapillomavirus (betaHPV) are implicated in skin carcinogenesis, but their exact role in keratinocyte transformation is poorly understood. We show an interaction of HPV5 and HPV8 oncoproteins E6 and E7 with the nuclear mitotic apparatus protein 1 (NuMA). Binding of E6 or E7 to NuMA induces little aneuploidy, cell cycle alterations, or aberrant centrosomes. Intracellular localization of NuMA is not altered by E6 and E7 expression in 2D cultures. However, the localization profile is predominantly cytoplasmic in 3D organotypic skin models. Both viral proteins colocalize with NuMA in interphase cells, while only E7 colocalizes with NuMA in mitotic cells. Intriguingly, a small subset of cells shows E7 at only one spindle pole, whereas NuMA is present at both poles. This dissimilar distribution of E7 at the spindle poles may alter cell differentiation, which may in turn be relevant for betaHPV-induced skin carcinogenesis.Peer reviewe
Software systems for operation, control, and monitoring of the EBEX instrument
We present the hardware and software systems implementing autonomous
operation, distributed real-time monitoring, and control for the EBEX
instrument. EBEX is a NASA-funded balloon-borne microwave polarimeter designed
for a 14 day Antarctic flight that circumnavigates the pole. To meet its
science goals the EBEX instrument autonomously executes several tasks in
parallel: it collects attitude data and maintains pointing control in order to
adhere to an observing schedule; tunes and operates up to 1920 TES bolometers
and 120 SQUID amplifiers controlled by as many as 30 embedded computers;
coordinates and dispatches jobs across an onboard computer network to manage
this detector readout system; logs over 3~GiB/hour of science and housekeeping
data to an onboard disk storage array; responds to a variety of commands and
exogenous events; and downlinks multiple heterogeneous data streams
representing a selected subset of the total logged data. Most of the systems
implementing these functions have been tested during a recent engineering
flight of the payload, and have proven to meet the target requirements. The
EBEX ground segment couples uplink and downlink hardware to a client-server
software stack, enabling real-time monitoring and command responsibility to be
distributed across the public internet or other standard computer networks.
Using the emerging dirfile standard as a uniform intermediate data format, a
variety of front end programs provide access to different components and views
of the downlinked data products. This distributed architecture was demonstrated
operating across multiple widely dispersed sites prior to and during the EBEX
engineering flight.Comment: 11 pages, to appear in Proceedings of SPIE Astronomical Telescopes
and Instrumentation 2010; adjusted metadata for arXiv submissio
Transition numérique et pratiques de recherche et d’enseignement supérieur en agronomie, environnement, alimentation et sciences vétérinaires à l’horizon 2040.
Pour citer ce document:Barzman M. (Coord.), Gerphagnon M. (Coord.), Mora O. (Coord.),Aubin-Houzelstein G., Bénard A., Martin C., Baron G.L, Bouchet F., Dibie-Barthélémy J., Gibrat J.F., Hodson S., Lhoste E., Moulier-Boutang Y., Perrot S., Phung F., Pichot C., Siné M., Venin T. 2019. Transition numérique et pratiques de recherche et d’enseignement supérieur en agronomie, environnement, alimentation et sciences vétérinaires à l’horizon 2040.INRA, France, 161pagesTransition numérique et pratiques de recherche et d’enseignement supérieur en agronomie, environnement, alimentation et sciences vétérinaires à l’horizon 2040
TRY plant trait database - enhanced coverage and open access
Plant traits-the morphological, anatomical, physiological, biochemical and phenological characteristics of plants-determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait-based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits-almost complete coverage for 'plant growth form'. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait-environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives
First implementation of TES bolometer arrays with SQUID-based multiplexed readout on a balloon-borne platform
EBEX (the E and B EXperiment) is a balloon-borne telescope designed to measure the polarisation of the cosmic microwave background radiation. During a two week long duration science flight over Antarctica, EBEX will operate 768, 384 and 280 spider-web transition edge sensor (TES) bolometers at 150, 250 and 410 GHz, respectively. The 10-hour EBEX engineering flight in June 2009 over New Mexico and Arizona provided the first usage of both a large array of TES bolometers and a Superconducting QUantum Interference Device (SQUID) based multiplexed readout in a space-like environment. This successful demonstration increases the technology readiness level of these bolometers and the associated readout system for future space missions. A total of 82, 49 and 82 TES detectors were operated during the engineering flight at 150, 250 and 410 GHz. The sensors were read out with a new SQUID-based digital frequency domain multiplexed readout system that was designed to meet the low power consumption and robust autonomous operation requirements presented by a balloon experiment. Here we describe the system and the remote, automated tuning of the bolometers and SQUIDs. We compare results from tuning at float to ground, and discuss bolometer performance during fligh
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