109 research outputs found

    The use of intra-articular aneshesia as a diagnostic tool in canine lameness

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    Lameness in dogs may be difficult to localize because of mild pathologic changes or inconclusive clinical findings. Intra-articular anesthesia is proposed as a diagnostic method to localize the source of lameness. After a description of the preparation, technique and puncture sites, an overview is given of a series of patients admitted for different joint problems. Intra-articular anesthesia proved to be applicable in any joint, provided that the clinician was experienced and the dog was under sedation. In 87% of the cases, intra-articular anesthesia was positive. Medial coronoid disease of the elbow joint was the most frequent indication for intra-articular anesthesia

    Functional brain imaging of serotonin-2A receptors in impulsive dogs: a pilot study

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    Impulsive, disinhibited behavior in dogs, which comes to expression as aggression, has a major impact on public health. Measures taken without a real understanding of the underlying pathology are unlikely to be effective. It would therefore be not only of pathophysiological but also of clinical relevance to develop a research paradigm to investigate this aberrant behavior in dogs. The first aim of this article is to review the literature concerning functional-anatomical and biochemical research on animal impulsivity. On the basis of this research, a hypothesis involving the prefrontal serotonin-2A receptor in the frontal cortex is generated and the feasibility of quantifying the 5-HT2A receptor with Single Photon Emission Computed Tomography (SPECT) and the highly selective receptor radioligand I-123-5I-R91150 is presented in a pilot study. If confirmed, this hypothesis may lead to the development of an in vivo research tool for investigating behavioral disorders and a modality for monitoring the effects of pharmacologic interventions and behavior therapy
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