144 research outputs found
Rydberg stabilization of atoms in strong fields: the "magic mountain" in the chaotic sea
We discuss the classical problem of an hydrogen atom interacting with a monochromatic field. We illustrate in particular, analytically and numerically, the stabilization mechanism and give theoretical expressions for the stabilization borders
A Hennessy-Milner Theorem for ATL with Imperfect Information
We show that a history-based variant of alternating bisimulation with
imperfect information allows it to be related to a variant of Alternating-time
Temporal Logic (ATL) with imperfect information by a full Hennessy-Milner
theorem. The variant of ATL we consider has a common knowledge semantics, which
requires that the uniform strategy available for a coalition to accomplish some
goal must be common knowledge inside the coalition, while other semantic
variants of ATL with imperfect information do not accommodate a Hennessy-Milner
theorem. We also show that the existence of a history-based alternating
bisimulation between two finite Concurrent Game Structures with imperfect
information (iCGS) is undecidable
Two cases of angioimmunoblastic T-cell lymphoma with concomitant positive serology for acute Epstein-Barr virus infection
TL) is a rare type of peripheral T-celllymphoma. Epstein-Barr virus (EBV) isknown to be associated with pathogenesisand histological progression of AITL andthe onset of the disease often mimics aninfectious process. Here we describe twocases of patients with serology for acuteEBV infection at the onset of AITL.IntroductionAngioimmunoblastic T-cell lymphom
Dynamical Localization: Hydrogen Atoms in Magnetic and Microwave fields
We show that dynamical localization for excited hydrogen atoms in magnetic
and microwave fields takes place at quite low microwave frequency much lower
than the Kepler frequency. The estimates of localization length are given for
different parameter regimes, showing that the quantum delocalization border
drops significantly as compared to the case of zero magnetic field. This opens
up broad possibilities for laboratory investigations.Comment: revtex, 11 pages, 3 figures, to appear in Phys. Rev. A, Feb (1997
An Outlook into the Future of Egocentric Vision
What will the future be? We wonder! In this survey, we explore the gap
between current research in egocentric vision and the ever-anticipated future,
where wearable computing, with outward facing cameras and digital overlays, is
expected to be integrated in our every day lives. To understand this gap, the
article starts by envisaging the future through character-based stories,
showcasing through examples the limitations of current technology. We then
provide a mapping between this future and previously defined research tasks.
For each task, we survey its seminal works, current state-of-the-art
methodologies and available datasets, then reflect on shortcomings that limit
its applicability to future research. Note that this survey focuses on software
models for egocentric vision, independent of any specific hardware. The paper
concludes with recommendations for areas of immediate explorations so as to
unlock our path to the future always-on, personalised and life-enhancing
egocentric vision.Comment: We invite comments, suggestions and corrections here:
https://openreview.net/forum?id=V3974SUk1
Spur cells in liver cirrhosis are predictive of acute-on-chronic liver failure and liver-related mortality regardless of severe anaemia
Lay SummaryChronic anaemia is a frequent finding in liver cirrhosis and spur cell anaemia has been shown to be an uncommon non-immune haemolytic disease typically related to advanced-liver disease. In our study, spur cell anaemia (spur cells >5%) was found in almost 10% of outpatient cirrhotics and was significantly related to more decompensated disease, higher incidence of ACLF and 1 year liver-related mortality. More importantly, the vast majority of patients with high percentage of spur cells did not have severe anaemia. Therefore, spur cells should be searched for in patients with advanced liver disease by a simple blood smear evaluation, even in the absence of significant anaemia, because of relevant prognostic impact and in order to prioritize patients to intensive management and possibly liver transplantation.Chronic anaemia in advanced liver disease is a frequent finding. The aim was to explore the clinical impact of spur cell anaemia, a rare entity typically associated with end-stage of the disease. One-hundred and nineteen patients (73.9% males) with liver cirrhosis of any etiology were included. Patients with bone marrow diseases, nutrients deficiencies and hepatocellular carcinoma were excluded. In all patients, a blood sample was collected to check for the presence of spur cells on blood smear. A complete blood biochemical panel was recorded together with Child-Pugh (CP) score and Model for End-Stage Liver Disease (MELD) score. For each patients, clinically relevant events, such as acute-on-chronic liver failure (ACLF) and 1 year liver-related mortality, were registered. Patients were then grouped according to the percentage of spur cells at smear (> 5%, 1-5%, < 1%). Severe anaemia was defined as haemoglobin levels lower than 8 g/dL. 9.2% of subjects had > 5% spur cells, only 2 had evidence of haemolysis. In patients with > 5% spur cells, haemoglobin and albumin were lower compared with the other sub-group, while MELD score, CP score, International Normalized Ratio, ferritin, creatinine and unconjugated bilirubin were higher. Patients with more spur cells were more decompensated and developed more frequently ACLF. ACLF and liver-related mortality were significantly and independently associated with the presence of > 5% spur cells but not with baseline severe anaemia. Cirrhotic patients have a fairly high prevalence of spur cells, not always associated with severe haemolytic anaemia. The presence of spur red cells is per se associated with a worse prognosis and, therefore, should be always evaluated to prioritize patients for intensive management and eventually liver transplantation
Red Blood Cell Morphologic Abnormalities in Patients Hospitalized for COVID-19
Peripheral blood smear is a simple laboratory tool, which remains of invaluable help for diagnosing primary and secondary abnormalities of blood cells despite advances in automated and molecular techniques. Red blood cells (RBCs) abnormalities are known to occur in many viral infections, typically in the form of mild normo-microcytic anemia. While several hematological alterations at automated complete blood count (including neutrophilia, lymphopenia, and increased red cell distribution widthâRDW) have been consistently associated with severity of COVID-19, there is scarce information on RBCs morphological abnormalities, mainly as case-reports or small series of patients, which are hardly comparable due to heterogeneity in sampling times and definition of illness severity. We report here a systematic evaluation of RBCs morphology at peripheral blood smear in COVID-19 patients within the first 72 h from hospital admission. One hundred and fifteen patients were included, with detailed collection of other clinical variables and follow-up. A certain degree of abnormalities in RBCs morphology was observed in 75 (65%) patients. Heterogenous alterations were noted, with spiculated cells being the more frequent morphology. The group with >10% RBCs abnormalities had more consistent lymphopenia and thrombocytopenia compared to those without abnormalities or <10% RBCs abnormalities (p < 0.018, and p < 0.021, respectively), thus underpinning a possible association with an overall more sustained immune-inflammatory âstressâ hematopoiesis. Follow-up analysis showed a different mortality rate across groups, with the highest rate in those with more frequent RBCs morphological alterations compared to those with <10% or no abnormalities (41.9%, vs. 20.5%, vs. 12.5%, respectively, p = 0.012). Despite the inherent limitations of such simple association, our results point out towards further studies on erythropoiesis alterations in the pathophysiology of COVID-19
Machine detector interface for the future circular collider
The international Future Circular Collider (FCC) study aims at a design of
, , colliders to be built in a new 100 km tunnel in the Geneva
region. The collider (FCC-ee) has a centre of mass energy range
between 90 (Z-pole) and 375 GeV (tt_bar). To reach such unprecedented energies
and luminosities, the design of the interaction region is crucial. The
crab-waist collision scheme has been chosen for the design and it will be
compatible with all beam energies. In this paper we will describe the machine
detector interface layout including the solenoid compensation scheme. We will
describe how this layout fulfills all the requirements set by the parameters
table and by the physical constraints. We will summarize the studies of the
impact of the synchrotron radiation, the analysis of trapped modes and of the
backgrounds induced by single beam and luminosity effects giving an estimate of
the losses in the interaction region and in the detector.Comment: 6 pages, 7 figures, 62th ICFA ABDW on High Luminosity Circular
Colliders, eeFACT2018, Hong Kong, Chin
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