CO2 Laser Treatment in Idiopathic Scrotal Calcinosis: A Case Series

Background: Idiopathic scrotal calcinosis (ISC) is a benign and uncommon condition characterized by the presence of multiple and calcified nodules of the scrotum without disorders in the calcium/phosphorous metabolism. The condition is usually asymptomatic. Various treatments are available. Surgery is the traditional treatment for ISC, as it allows a histopathological exam. However, newer treatments, such as ablative lasers, have been proposed with very good results.Methods: In this article, we report our experience in the treatment of ISC with a CO2 laser. Five patients affected by ISC were enrolled for CO2 laser treatment.Results: All patients had excellent healing. Four patients reported minimal scarring. No bleeding was reported after the procedure. Two patients reported itching and were treated with oral antibiotics and antihistamine drugs.Conclusion: The CO2 super pulsed laser is a fast and effective way to treat ISC and may be an alternative to traditional surgery in this condition

Severe local skin reaction after the application of ingenol mebutate gel treated by photodynamic therapy: A case report

Ingenol mebutate (IM) was recently introduced for the treatment of actinic keratosis (AK). It is considered a safe and effective treatment in spite of local reactions frequently reported. These reactions may consist of erythema, flaking, crusting, swelling, vesicles and erosions, and would usually spontaneously recede within 20–30 days. We reported a case of a patient affected by multiple actinic keratosis of the scalp treated with IM. The patient reported a severe reaction that was not solved in two months. We decided to treat the reaction with photodynamic therapy and aminolevulinic acid. This treatment was demonstrated to be effective in solving this severe side effec

Severe local skin reaction after the application of ingenol mebutate gel treated by photodynamic therapy: A case report

none6Ingenol mebutate (IM) was recently introduced for the treatment of actinic keratosis (AK). It is considered a safe and effective treatment in spite of local reactions frequently reported. These reactions may consist of erythema, flaking, crusting, swelling, vesicles and erosions, and would usually spontaneously recede within 20–30 days. We reported a case of a patient affected by multiple actinic keratosis of the scalp treated with IM. The patient reported a severe reaction that was not solved in two months. We decided to treat the reaction with photodynamic therapy and aminolevulinic acid. This treatment was demonstrated to be effective in solving this severe side effectmixedNegosanti, Luca; Sgarzani, Rossella; Santoli, Matteo; Negosanti, Massimino; Banzola, Nicoletta; Negosanti, Francesca .Negosanti, Luca; Sgarzani, Rossella; Santoli, Matteo; Negosanti, Massimino; Banzola, Nicoletta; Negosanti, Francesca

Association of Surgery and Pulsed Dye Laser for the Treatment of an Ear Keloid: A Case Report

Background and Objective: A keloidal scar is a benign hyperproliferation of dermal collagen resulting from abnormal healing. The ear is probably the most frequent interested area and these kind of keloids are responsible for cosmetic disfigurement. Numerous treatments have been applied for keloids. Surgery is generally not indicated because of the high risk of recurrence while laser technologies have been tested to prevent and treat hypertrophic scars. The association between laser and surgery was poorly reported in literature. We decided to associate surgery and pulsed Dye laser in just one case of ear keloid. Materials and Methods: We treated a female patient affected by an earlobe keloid with a surgical excision and subsequent pulsed Dye laser treatment. Results: The aesthetic result was good and no signs of recurrence was observed. Conclusion: We believe that the association between surgery and Pulsed-Dye laser can be useful to treat keloids reducing the risk of recurrence

Photodynamic therapy with topical aminolevulinic acid

Photodynamic therapy (PDT) is a relatively new therapy in dermatology that uses the topical application of a porphyrin derivative to selectively destroy a cutaneous target. The action is implemented by the application of a specific light frequency. The ability of porphyrin to selectively target tumor tissue has been known since the 1960s. In the late 1970s, the underlying mechanism was defined, and Dougherty\u2019s discovery of the first chromophore led to the production and commercialization of Photofrin\uae. Many other chromophores that can act as photosensitizers have been studied since then, with aminolevulinic acid currently the most commonly used chromophore in clinical practice. PDT is simple, minimally invasive and can be administered on an outpatient basis. The efficacy of PDT has been proven for actinic keratosis, Bowen\u2019s disease and basal cell carcinoma; another of its well-known applications is the treatment of photoaging. Indications for its use are continuously increasing, and promising results are reported for various skin diseases. In this paper we report the mechanism of action of PDT with aminolevulinic acid, the literature concerning the most common diseases treated with PDT and the subsequent level of evidence

Is It Possible to Reshape the Body and Tone It at the Same Time? Schwarzy: The New Technology for Body Sculpting

Background and Objective: In recent years, a strong desire for slimmer and healthier-looking bodies has grown in the population. The aim of this study was to evaluate the effectiveness and safeness of the new technology Flat Magnetic Stimulation for buttock and abdomen remodeling in athletic subjects. Methods: A total of 49 patients (31 females and 18 males) were enrolled. Patients’ digital photos and buttocks/abdomen circumference measurements were taken to assess and monitor the effectiveness of treatment on muscle firming. The level of patient satisfaction was evaluated by a questionnaire based on a seven point Likert scale. Average scores were calculated at a 1-month follow-up (FU). Results: A significant increase in the buttocks’ mean circumference from 85.5 ± 0.7 cm to 88.5 ± 0.7 cm (p p Conclusions: Our data show that FMS treatment could be used as an effective mechanism for muscle toning

Fractional Q-Switched 1064 nm Laser for Treatment of Atrophic Scars in Asian Skin

Background and Objectives: Asian patients with Fitzpatrick skin type III–IV are a less studied subtype of patients in the medical literature. Q-Switched, 1064 nm neodymium-doped yttrium aluminum garnet (Nd: YAG) laser with a fractionated beam profile (QSF) is a new modality that was reported to be effective in the treatment of scars. This study aims to evaluate the efficacy and safety of QSF Nd: YAG laser in treating scars in Asian patients. Materials and Methods: A total of 29 Subjects were treated with 1064 nm QSF laser. Each patients had three treatments with a fractionated microlens array handpiece every 8 weeks). Efficacy of treatment was evaluated using the Goodman and Baron’s quantitative grading scale before and 3 months after the last treatment. Results: All 29 patients treated had significant improvement of acne scars according to Goodman and Baron’s Quantitative Global Acne Scarring Grading System. No side effect has been observed except some minor erythematous reactions in three patients. Conclusions: Our results confirm that the 1064 nm QSF Nd: YAG laser is a safe and effective technique for treating scars in Asians

Combination of Specific Vascular Lasers and Vascular Intense Pulsed Light Improves Facial Telangiectasias and Redness

Background and objectives: Facial telangiectasias are dilated blood vessels that can represent a cosmetic issue for patients. They may be associated with other conditions, such as rosacea. Laser and light treatments are nowadays becoming a cornerstone in the management of these lesions. Materials and Methods: In total, 68 patients seeking medical treatment for facial telangiectasias were enrolled from 1 March 2019 to 1 March 2020 at the Dermatological Unit of Magna Graecia University (Catanzaro, Italy). A protocol consisting of a 1064 Nd:YAG laser for darker blue telangiectasias and 532 nm Nd:YAG for red lesions followed by intense pulsed light with an optimized spectrum for vascular lesion 3 weeks after the first procedure was proposed. A three-month follow-up visit assessed patient’s satisfaction using a visual analog scale (VAS). Two dermatologists measured clinical results using a 4-point scale, comparing pictures before treatment and at follow-up. Results: A total of 68 patients (32 males and 36 females) completed the study, performing all requested treatments. No severe side effects were reported. Patient satisfaction was very high (8.15 ± 1.05 out of a 10-point VAS scale), as well as dermatologists’ clinical evaluations (2.19 ± 0.74 out of 3). Conclusions: The combination of vascular lasers and Vascular Intense Pulsed Light acting specifically on small blood vessels may help to improve the aesthetic outcome, reducing side effects. A prospective study with a larger number of participants will be necessary to confirm this study’s findings