Another treatment option for relapsed or refractory chronic lymphocytic leukaemia.

We hereby report the clinical and biologic features of 33 of 4680 (0.7%) patients with chronic lymphocytic leukemia (CLL), managed at 10 Italian centers, who developed Hodgkin lymphoma (HL), a rare variant of Richter syndrome. The median age at CLL and at HL diagnosis were 61 years (range 41-80) and 70 years (range 46-82), respectively, with a median interval from CLL to the diagnosis of HL of 90 months (range 0-258). In 3 cases, CLL and HL were diagnosed simultaneously. Hl was characterized by advanced stage in 79% of cases, International Prognostic Score (IPS) ≥4 in 50%, extranodal involvement in 39%, B symptoms in 70%. Prior treatment for CLL had been received by 82% of patients and included fludarabine in 67%. Coexistence of CLL and HL was detected in the same bioptic tissue in 87% of cases. The most common administered treatment was the ABVD regimen given to 22 patients (66.6%). The complete response (CR) rate after ABVD was 68%, and was influenced by the IPS (P = .03) and interval from the last CLL treatment (P = .057). Survival from HL was also influenced by the IPS (P = .006) and time from the last CLL treatment (P = .047). The achievement of CR with ABVD was the only significant and independent factor predicting survival (P = .037). Taken together, our results show that the IPS and the interval from the prior CLL treatment influence the likelihood of achieving CR after ABVD, which is the most important factor predicting survival of patients with CLL developing HL

Star-Invertibility and tt-finite character in Integral Domains

Let $A$ be an integral domain. We study new conditions on families of integral ideals of $A$ in order to get that $A$ is of $t$-finite character (i.e., each nonzero element of $A$ is contained in finitely many $t$-maximal ideals). We also investigate problems connected with the local invertibility of ideals.Comment: 16 page

Social Identity and the Mexican Community

The election of President Trump can be shown to negatively impact the Mexican community through social identity theory. Since his election, President Trump has passed policies controlling immigration and uses harmful language to describe Mexicans, such as rapists and criminals. To investigate the impact that the presidency has had on the Mexican Community the author choose to analyze this influence with social identity theory. Social identity theory proposes that individuals’ self-concept is based on their identification to their ingroup, and when this ingroup (Mexican) is viewed unfavorably by the outgroup (Anglo-American), negative social identity occurs. The author interviewed 16 participants that work and are students in a university and identify as Mexican or Mexican American. Findings support that there was a difference in the participants who experienced negative social identity. Those participants with American citizenship indicated to have negative social identity when they spoke about Trump’s Presidency and policies, however, those participants without American citizenship such as DACA recipients showed to be discouraged more so because of the uncertainty of their future with immigration policies, and not negative social identity. My hypothesis that negative social identity will influence motivation in lifestyle was not supported

Content Teachers' Written Comments on Their Life-long English Language Profiles

CLIL in Italy has been compulsory by law since 2003 (Moratti’s Law) for the last year of all secondary schools. Subject-matter teachers were chosen to be the CLIL teachers, and only in 2012 did methodological and linguistic training begin (provided by universities all over the country). This study explores the profile of content teachers attending CLIL training not in terms of their linguistic competence but in terms of their relationship with English as an additional language. To do so, 115 trainees were asked to fill in a questionnaire composed of 10 open-ended questions and 2 close-ended ones. This questionnaire had both a research and training goal, since it was submitted at the beginning of the training course to investigate content teachers’ perceived linguistic profiles, which served as a psychological and pedagogical starting point for the course. Results show that content teachers have a specific linguistic identity and have had similar past experiences with the English language. These results could have repercussions and be exported to other training programmes, especially in terms of shifting teachers’ personae from subject-matter to fully-fledged CLIL teachers

Dark Matter Gravitinos and Baryons via Q-ball decay in the Gauge-Mediated MSSM

We show that late Q-ball decay in the MSSM with gauge-mediated SUSY breaking can provide a natural source of non-thermal NLSPs which subsequently decay to gravitino dark matter without violating nucleosynthesis constraints. To show this, we perform a global analysis of Q-ball formation and decay in Affleck-Dine baryogenesis for a d = 6 (u^{c}d^{c}d^{c})^2 flat direction of the gauge-mediated MSSM. A general phenomenological potential for the flat-direction is studied and the Q-ball decay properties are obtained as a function of its parameters. The corresponding gravitino mass necessary to account for dark matter is then determined for the case of stau NLSPs. The decay temperature depends on the charge of the Q-balls, which is determined by the fragmentation of the AD condensate. Different fragmentation scenarios are considered, and the final non-thermal NLSP density from Q-ball decay and NLSP annihilation is determined. Particular care is taken to establish that NLSPs from Q-ball decay become homogeneous and non-relativistic prior to annihilation. The gravitino mass necessary for dark matter is naturally consistent with the theoretical gravitino mass in the gauge-mediation model.Comment: 16 pages, LaTeX, 2 figure