Trends in cancer mortality in Switzerland, 1980-2001

Trends in cancer mortality in Switzerland were analysed over the period 1980-2001, on the basis of the World Health Organization database. Appropriately developed correction factors were utilized for the period before 1995, to allow for spurious trends introduced by the change between the 8th and the 10th revisions of the ICD. Steady declines in cancer mortality were observed, particularly from the mid-1980s onwards. Over the last decade, the fall in overall age-standardized (world standard) cancer mortality was 11.1% in men (from 158.1 in 1990-1991 to 140.6/100 000 in 2000-2001) and 7.6% in women (from 91.6 to 84.7/100 000), and the decline was larger in truncated rates from 35 to 64 years (-18.0 and -9.7%). In men, all major tobacco and alcohol neoplasms have declined until the late 1990s but have levelled off over the last few years, reflecting recent trends in alcohol and tobacco consumption. The fall in male lung cancer mortality was 20% over the last decade (from 42.9 to 34.3/100 000). In contrast, lung cancer mortality in women has steadily increased by 38% between 1981 and 1991 and by 47% between 1991 and 2001, to reach 10.7/100 000 at all ages and 18.3 at age 35 to 64, due to increased prevalence of smoking in subsequent generations of Swiss women. Other sites showing substantial declines include stomach and colorectum in both sexes, (cervix) uteri and breast in women. Likewise, prostate cancer showed modest favourable trends after 1995. Steady declines were observed for leukaemias, Hodgkin's disease and testicular cancer, namely, the neoplasms most influenced by therapeutic improvements, while trends in lymphomas and myeloma showed no clear pattern. [Authors]]]> Neoplasms oai:serval.unil.ch:BIB_4FDAD003069F 2022-05-07T01:17:43Z <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_4FDAD003069F The Arid Margins of Northern Syria: Land Occupation and Modes of Exploitation in the Bronze Age Geyer, B. Al-Dbiyat, M. Awad, N. Barge, O. Besançon, J. Jaubert, R. info:eu-repo/semantics/bookPart incollection 2008 Urban and Natural Landscapes of an Ancient Syrian Capital, Settlement and Environment at Tell Mishrifeh/Qatna and in Central-Western Syria oai:serval.unil.ch:BIB_4FDAF0543B78 2022-05-07T01:17:43Z openaire documents urnserval <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_4FDAF0543B78 Adverse effects of industrial multiwalled carbon nanotubes on human pulmonary cells info:doi:10.1080/15287390802476991 info:eu-repo/semantics/altIdentifier/doi/10.1080/15287390802476991 info:eu-repo/semantics/altIdentifier/pmid/19034795 Tabet, Lyes Bussy, Cyrill Amara, Nadia Setyan, Ari Grodet, Alain Rossi Michel, J. Pairon, Jean-Claude Boczkowski, Jorge Lanone, Sophie info:eu-repo/semantics/article article 2009 Journal of Toxicology and Environmental Health. Part A, vol. 72, no. 2, pp. 60-73 info:eu-repo/semantics/altIdentifier/pissn/1528-7394 Nanotubes, Carbon; Asbestos, Amphibole; Asbestos, Serpentine; Soot; Oxidative Stress; Pulmonary Alveoli; Epithelial Cells; Apoptosis eng https://serval.unil.ch/resource/serval:BIB_4FDAF0543B78.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_4FDAF0543B789 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_4FDAF0543B789 info:eu-repo/semantics/submittedVersion info:eu-repo/semantics/openAccess Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer application/pdf oai:serval.unil.ch:BIB_4FDB851850ED 2022-05-07T01:17:43Z <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_4FDB851850ED « Digital stylistic analyses in “PhraseoRom”: methodological and epistemological issues in a multidisciplinary project » Vidotto, Ilaria Jacquot, Clémence Gonon, Laetitia info:eu-repo/semantics/conferenceObject inproceedings Digital Stylistics in Romance Studies and Beyond  eng oai:serval.unil.ch:BIB_4FDC597DC998 2022-05-07T01:17:43Z <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_4FDC597DC998 Distinct but overlapping T helper epitopes in the 37-58 region of SSX-2 info:doi:10.1016/j.clim.2004.08.014 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.clim.2004.08.014 info:eu-repo/semantics/altIdentifier/pmid/15596411 Ayyoub, M. Merlo, A. Hesdorffer, C. S. Speiser, D. Rimoldi, D. Cerottini, J. C. Ritter, G. Chen, Y. T. Old, L. J. Stevanovic, S. Valmori, D. info:eu-repo/semantics/article article 2005-01 Clinical Immunology, vol. 114, no. 1, pp. 70-8 info:eu-repo/semantics/altIdentifier/pissn/1521-6616 <![CDATA[Because of their specific expression in tumors of different histological types, the products of the SSX genes are important candidate targets for development of cancer vaccines. We have previously identified two immunodominant SSX-2-derived T cell epitopes recognized by HLA-A2-restricted CD8+ T cells (SSX-2 41-49) and HLA-DR11-restricted CD4+ T cells (SSX-2 45-59), respectively. In this study, we report the identification of an HLA-DR3-restricted epitope mapping to the 37-51 region of SSX-2, overlapping both previously identified epitopes. As about one fifth of individuals from several major ethnic groups express HLA-DR3, the identification of this epitope significantly increases the percent of patients that are expected to mount specific CD4+ T cell responses following vaccination with peptides in this region of SSX-2. Retrieval of multiple overlapping epitopes in a defined region of SSX-2 protein suggests the presence of a "hot spot" for T cell recognition that may prove sufficient for the induction of immune responses

Mortality Patterns and Trends for Lung Cancer and Other Tobacco-Related Cancers in the Americas, 1955-1989

Mortality from cancers of the oral cavity and pharynx, oesphagus, larynx and lung between 1955 and 1989 has been analysed for USA, Canada and 14 countries in Latin America. Among males, Uruguay, Cuba, Argentina and Puerto Rico have the highest rates for all sites, and Peru, Ecuador, Dominican Republic, Mexico and Colombia have the lowest rates. Among females, Cuba, Colombia and Puerto Rico rank high for all sites, and Mexico, Paraguay, Ecuador and Peru rank low. For both sexes, lung cancer mortality rates from the US and Canada are high, whereas rates from other sites are intermediate. An increasing trend in lung cancer mortality over time is shown in all countries except Cuba (no changes), Argentina, Paraguay and Peru (decreasing trend). In Latin America, the tobacco-related lung cancer epidemic is in its early phase among males, and very early phase among female

Pancreatic cancer mortality in Europe: the leveling of an epidemic

Mortality rates from pancreatic cancer have increased throughout Europe between the late 1950s and the 1980s. Trends in 22 European countries, the European Union (EU) and 6 selected eastern European countries have been updated using official death certification data for pancreatic cancer abstracted from the WHO database over the period 1980 to 1999. In EU men, a rise from 7.2 to 7.5/100,000 was observed between the early and the late 1980s, followed by a leveling off in the 1990s. For women, rates tended to rise up to the early 1990s, and to level off thereafter around 4.7/100,000. In eastern countries, rates for both sexes rose between the early 1980s and the mid-1990s, and leveled off thereafter around 8.5/100,000 men and 5/100,000 women. Thus, rates for men only were higher in Eastern Europe than in the EU. This analysis first documents a leveling of pancreatic cancer mortality in Europe, after decades of steady rises. This is partly or largely attributable to the decline in smoking, at least in men, but other factors, including mainly nutrition and diet, may also have played some role on these trends. [Authors]]]> Mortality ; Pancreatic Neoplasms oai:serval.unil.ch:BIB_F326E20D1607 2022-05-07T01:30:01Z openaire documents urnserval <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_F326E20D1607 Mouse Grueneberg ganglion neurons share molecular and functional features with C. elegans amphid neurons. info:doi:10.3389/fnbeh.2013.00193 info:eu-repo/semantics/altIdentifier/doi/10.3389/fnbeh.2013.00193 info:eu-repo/semantics/altIdentifier/pmid/24367309 Brechbühl, J. Moine, F. Broillet, M.C. info:eu-repo/semantics/article article 2013 Frontiers in Behavioral Neuroscience, vol. 7, pp. 193 info:eu-repo/semantics/altIdentifier/eissn/1662-5153 urn:issn:1662-5153 <![CDATA[The mouse Grueneberg ganglion (GG) is an olfactory subsystem located at the tip of the nose close to the entry of the naris. It comprises neurons that are both sensitive to cold temperature and play an important role in the detection of alarm pheromones (APs). This chemical modality may be essential for species survival. Interestingly, GG neurons display an atypical mammalian olfactory morphology with neurons bearing deeply invaginated cilia mostly covered by ensheathing glial cells. We had previously noticed their morphological resemblance with the chemosensory amphid neurons found in the anterior region of the head of Caenorhabditis elegans (C. elegans). We demonstrate here further molecular and functional similarities. Thus, we found an orthologous expression of molecular signaling elements that was furthermore restricted to similar specific subcellular localizations. Calcium imaging also revealed a ligand selectivity for the methylated thiazole odorants that amphid neurons are known to detect. Cellular responses from GG neurons evoked by chemical or temperature stimuli were also partially cGMP-dependent. In addition, we found that, although behaviors depending on temperature sensing in the mouse, such as huddling and thermotaxis did not implicate the GG, the thermosensitivity modulated the chemosensitivity at the level of single GG neurons. Thus, the striking similarities with the chemosensory amphid neurons of C. elegans conferred to the mouse GG neurons unique multimodal sensory properties

Oral contraceptives and colorectal cancer

BACKGROUND: Only limited information and understanding are available on the potential relation between oral contraceptive use and the risk of colorectal cancer. Further data on the issue are therefore useful and may help informed choice of contraception. METHODS AND RESULTS: Data were derived from a case-control study of colorectal cancer conducted between 1992 and 2001 in the Swiss Canton of Vaud, including 131 women with colorectal cancer and 373 controls admitted in the same hospital as the cases with diagnosis of acute, non-neoplastic disease, unrelated to long-term modification of diet. Oral contraceptive use was reported by 11% of cases versus 17% of controls, corresponding to multivariate odds ratio of 0.8 (95% CI: 0.4-1.7). The odds ratio was non-significantly below unity across strata of duration, time since first and last oral contraceptive use. CONCLUSION: These findings add further evidence on a possible inverse relation between oral contraceptive and colorectal cancer risk. [authors]]]> oai:serval.unil.ch:BIB_79B5CE1ABB91 2022-05-07T01:20:58Z openaire documents urnserval <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_79B5CE1ABB91 Correlated genetic effects on reproduction define a domestication syndrome in a forest tree. info:doi:10.1111/eva.12252 info:eu-repo/semantics/altIdentifier/doi/10.1111/eva.12252 info:eu-repo/semantics/altIdentifier/pmid/25926884 Santos-Del-Blanco, L. Alía, R. González-Martínez, S.C. Sampedro, L. Lario, F. Climent, J. info:eu-repo/semantics/article article 2015 Evolutionary Applications, vol. 8, no. 4, pp. 403-410 info:eu-repo/semantics/altIdentifier/eissn/1752-4571 urn:issn:1752-4571 <![CDATA[Compared to natural selection, domestication implies a dramatic change in traits linked to fitness. A number of traits conferring fitness in the wild might be detrimental under domestication, and domesticated species typically differ from their ancestors in a set of traits known as the domestication syndrome. Specifically, trade-offs between growth and reproduction are well established across the tree of life. According to allocation theory, selection for growth rate is expected to indirectly alter life-history reproductive traits, diverting resources from reproduction to growth. Here we tested this hypothesis by examining the genetic change and correlated responses of reproductive traits as a result of selection for timber yield in the tree Pinus pinaster. Phenotypic selection was carried out in a natural population, and progenies from selected trees were compared with those of control trees in a common garden experiment. According to expectations, we detected a genetic change in important life-history traits due to selection. Specifically, threshold sizes for reproduction were much higher and reproductive investment relative to size significantly lower in the selected progenies just after a single artificial selection event. Our study helps to define the domestication syndrome in exploited forest trees and shows that changes affecting developmental pathways are relevant in domestication processes of long-lived plants

The Impact of Therapeutic Improvements in Reducing Peptic Ulcer Mortality in Europe

Trends in death certification rates from peptic ulcer between 1955 and 1989 have been analysed for 24 European countries on the basis of age-specific and age-standardized rates, and a log-linear model to estimate the effects of age, cohort of birth and period of death. For males, in all Western countries there were substantial declines in mortality. In the late 1950s, the range of variation of the world standardized rates was between 4/100 000 in France and 17.8 in Portugal. In the late 1980s, only Ireland had a rate over 5/100 000, and values for most Western countries ranged between 2 and 4/100 000. The average fall in rates over the last three decades was 56%. Of this, a high proportion (45%) was registered between 1975 and 1984. In Eastern Europe, no systematic change was observed until the early 1970s, but over the last 15 years peptic ulcer mortality declined by an average of 20%. In 1985-1989 the lowest rate was 4.5/100 000 in Bulgaria, and for all other countries peptic ulcer mortality ranged between 5 and 7.2/100 000. Peptic ulcer mortality was substantially lower in females, and showed no appreciable modification in Western Europe, and several increases in Eastern Europe until the mid 1970s. Thereafter, mortality declined by an overall 25% in the West and 15% in the East. Earlier declines for males in Western Europe were chiefly related to a cohort effect, reflecting more favourable risk factor exposure {such as diet, Helicobacter pylori or smoking) of subsequent generations. The recent falls, in contrast, were mainly on a period of death basis indicating therapeutic advancements (including the introduction of H2-receptor-antagonists in the mid-1970s) as the major determinant. These falls correspond to about 20 000 deaths from peptic ulcer avoided every year in the whole of Europ

Lung cancer mortality in European women: recent trends and perspectives

BACKGROUND: Lung cancer mortality in men has been declining since the late 1980s in most European countries. In women, although rates are still appreciably lower than those for men, steady upward trends have been observed in most countries. To quantify the current and future lung cancer epidemic in European women, trends in lung cancer mortality in women over the last four decades were analyzed, with specific focus on the young. PATIENTS AND METHODS: Age-standardized (world standard) lung cancer mortality rates per 100 000 women--at all ages, and truncated 35-64 and 20-44 years--were derived from the WHO for the European Union (EU) as a whole and for 33 separate European countries. Joinpoint regression analysis was used to identify points where a significant change in trends occurred. RESULTS: In the EU overall, female lung cancer mortality rates rose by 23.8% between 1980-1981 and the early 1990-1991 (from 7.8 to 9.6/100 000), and by 16.1% thereafter, to reach the value of 11.2/100 000 in 2000-2001. Increases were smaller in the last decade in several countries. Only in England and Wales, Latvia, Lithuania, Russia and Ukraine did female lung cancer mortality show a decrease over the last decade. In several European countries, a decline in lung cancer mortality in young women (20-44 years) was observed over the last decade. CONCLUSIONS: Although female lung cancer mortality is still increasing in most European countries, the more favorable trends in young women over recent calendar years suggest that if effective interventions to control tobacco smoking in women are implemented, the lung cancer epidemic in European women will not reach the levels observed in the USA. [Authors]]]> Lung Neoplasms; Mortality; Female eng https://serval.unil.ch/resource/serval:BIB_1D2BD2A3B24C.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_1D2BD2A3B24C2 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_1D2BD2A3B24C2 info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/openAccess Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer application/pdf oai:serval.unil.ch:BIB_1D2BE11940C7 2022-05-07T01:11:58Z urnserval <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_1D2BE11940C7 Caffeine intake and CYP1A2 variants associated with high caffeine intake protect non-smokers from hypertension. info:doi:10.1093/hmg/dds137 info:eu-repo/semantics/altIdentifier/doi/10.1093/hmg/dds137 info:eu-repo/semantics/altIdentifier/pmid/22492992 Guessous, I. Dobrinas, M. Kutalik, Z. Pruijm, M. Ehret, G. Maillard, M. Bergmann, S. Beckmann, J.S. Cusi, D. Rizzi, F. Cappuccio, F. Cornuz, J. Paccaud, F. Mooser, V. Gaspoz, J.M. Waeber, G. Burnier, M. Vollenweider, P. Eap, C.B. Bochud, M. info:eu-repo/semantics/article article 2012 Human Molecular Genetics, vol. 21, no. 14, pp. 3283-3292 info:eu-repo/semantics/altIdentifier/eissn/1460-2083 urn:issn:0964-6906 <![CDATA[The 15q24.1 locus, including CYP1A2, is associated with blood pressure (BP). The CYP1A2 rs762551 C allele is associated with lower CYP1A2 enzyme activity. CYP1A2 metabolizes caffeine and is induced by smoking. The association of caffeine consumption with hypertension remains controversial. We explored the effects of CYP1A2 variants and CYP1A2 enzyme activity on BP, focusing on caffeine as the potential mediator of CYP1A2 effects. Four observational (n = 16 719) and one quasi-experimental studies (n = 106) including European adults were conducted. Outcome measures were BP, caffeine intake, CYP1A2 activity and polymorphisms rs762551, rs1133323 and rs1378942. CYP1A2 variants were associated with hypertension in non-smokers, but not in smokers (CYP1A2-smoking interaction P = 0.01). Odds ratios (95% CIs) for hypertension for rs762551 CC, CA and AA genotypes were 1 (reference), 0.78 (0.59-1.02) and 0.66 (0.50-0.86), respectively, P = 0.004. Results were similar for the other variants. Higher CYP1A2 activity was linearly associated with lower BP after quitting smoking (P = 0.049 and P = 0.02 for systolic and diastolic BP, respectively), but not while smoking. In non-smokers, the CYP1A2 variants were associated with higher reported caffeine intake, which in turn was associated with lower odds of hypertension and lower BP (P = 0.01). In Mendelian randomization analyses using rs1133323 as instrument, each cup of caffeinated beverage was negatively associated with systolic BP [-9.57 (-16.22, -2.91) mmHg]. The associations of CYP1A2 variants with BP were modified by reported caffeine intake. These observational and quasi-experimental results strongly support a causal role of CYP1A2 in BP control via caffeine intake

Trends in laryngeal cancer mortality in Europe

After a steady increase since the 1950s, laryngeal cancer mortality had tended to level off since the early 1980s in men from most European countries. To update trends in laryngeal cancer mortality in Europe, age-standardized (world standard) mortality rates per 100,000 were derived from the WHO mortality database for 33 European countries over the period 1980-2001. Jointpoint analysis was used to identify significant changes in mortality rates. In the European Union (EU) as a whole, male mortality declined by 0.8% per year between 1980 and 1989, by 2.8% between 1989 and 1995, by 5.3% between 1995 and 1998, and by 1.5% thereafter (rates were 5.1/100,000 in 1980-1981 and 3.3/100,000 in 2000-2001). This mainly reflects a decrease in rates in men from western and southern European countries, which had exceedingly high rates in the past. Male laryngeal mortality rose up to the early 1990s, and leveled off thereafter in several countries from central and eastern Europe. In 2000-2001 there was still a 10-15-fold variation in male laryngeal mortality between the highest rates in Croatia (7.9/100,000) and Hungary (7.7/100,000) and the lowest ones in Sweden (0.5/100,000) and Finland (0.8/100,000). Laryngeal cancer mortality was comparatively low in women from most European countries, with stable rates around 0.3/100,000 in the EU as a whole over the last 2 decades. Laryngeal cancer trends should be interpreted in terms of patterns and changes in exposure to alcohol and tobacco. Despite recent declines, the persistence of a wide variability in male laryngeal cancer mortality indicates that there is still ample scope for prevention of laryngeal cancer in Europe. [Ed.]]]> Laryngeal Neoplasms; Mortality eng oai:serval.unil.ch:BIB_E23DFD6660FA 2022-05-07T01:28:48Z openaire documents urnserval <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_E23DFD6660FA Why is there philosophy in India? Johannes, Bronkhorst Johannes, Bronkhorst (ed.) info:eu-repo/semantics/book book 1999 Indian philosophy, Indian history eng https://serval.unil.ch/resource/serval:BIB_E23DFD6660FA.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_E23DFD6660FA3 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_E23DFD6660FA3 info:eu-repo/semantics/submittedVersion info:eu-repo/semantics/openAccess Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer application/pdf oai:serval.unil.ch:BIB_E23E086D3432 2022-05-07T01:28:48Z <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_E23E086D3432 Compte-rendu : « Gwénola Réto, La bienveillance à l’école » https://halshs.archives-ouvertes.fr/halshs-03452642 Camille, Roelens info:eu-repo/semantics/article article 2021 Le Télémaque. Philosophie, Education, Société, no. 60 fre oai:serval.unil.ch:BIB_E23F61C3E477 2022-05-07T01:28:48Z openaire documents urnserval <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_E23F61C3E477 Bioterrorism: myth or reality? info:doi:10.1111/1469-0691.12713 info:eu-repo/semantics/altIdentifier/doi/10.1111/1469-0691.12713 info:eu-repo/semantics/altIdentifier/pmid/24920295 Greub, G. Grobusch, M.P. info:eu-repo/semantics/article article 2014 Clinical Microbiology and Infection, vol. 20, no. 6, pp. 485-487 info:eu-repo/semantics/altIdentifier/eissn/1469-0691 urn:issn:1198-743X eng https://serval.unil.ch/resource/serval:BIB_E23F61C3E477.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_E23F61C3E4776 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_E23F61C3E4776 info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/restrictedAccess Restricted: indefinite embargo Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer application/pdf oai:serval.unil.ch:BIB_E24085AADE3D 2022-05-07T01:28:48Z openaire documents <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_E24085AADE3D De la communauté à l’utopie : l’impact sociopolitique des théâtres postdramatiques https://www.fabula.org/revue/document12988.php Aurélien, Maignant info:eu-repo/semantics/article article 2020-06-01 Acta Fabula, vol. 6, no. 21 info:eu-repo/semantics/altIdentifier/pissn/1496-9610 fre https://serval.unil.ch/resource/serval:BIB_E24085AADE3D.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_E24085AADE3D7 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_E24085AADE3D7 info:eu-repo/semantics/acceptedVersion info:eu-repo/semantics/openAccess Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer application/pdf oai:serval.unil.ch:BIB_E24153DBE7DF 2022-05-07T01:28:48Z <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_E24153DBE7DF Assurance maladie et dépenses de santé : présentation Mougeot, Michel info:eu-repo/semantics/article article 2000 Revue d'économie politique, vol. 110, no. 4, pp. 447-456 info:eu-repo/semantics/altIdentifier/pissn/0373-2630 oai:serval.unil.ch:BIB_E241922E4472 2022-05-07T01:28:48Z <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_E241922E4472 Energy expenditure and whole body protein synthesis in very low birth weight (VLBW) infants info:eu-repo/semantics/altIdentifier/pmid/6580179 Schutz, Y. Catzeflis, C. Gudinchet, F. Micheli, J. Welsch, C. Arnaud, M. J. Jequier, E. info:eu-repo/semantics/article article 1983 Experientia Suppl, vol. 44, pp. 45-56 info:eu-repo/semantics/altIdentifier/pissn/0071-335X <![CDATA[To examine the rates of whole body protein synthesis and energy expenditure during the rapid growing period, premature infants of very low birth weight (VLBW) (less than 1500 g), appropriate for gestational age were kept under standard thermoneutrality conditions and received a formula diet providing 110 kcal/kg.d metabolisable energy (ME) and 3.3 g protein/kg.d. Their energy expenditure was measured by open circuit indirect calorimetry. Nitrogen turnover and whole body protein synthesis and catabolism were determined using repeated oral administration of 15N-glycine for 60-72 h followed by the analysis of 15N-enrichment in urinary urea. These VLBW infants grew at an average rate of 15 g/kg.d. About half of the ME intake (i.e. 50 kcal/kg.d) was invested in weight gain while the remainder (i.e. 60 kcal/kg.d) was oxidised. The energy equivalent of the weight gain (i.e. the amount of energy stored per g weight gain) and the N balance indicated that lean tissue made up approximately 2/3 of the weight gained and fat tissue the remaining 1/3. The plateau value for 15N enrichment reached on the third day of administration allowed us to calculate a rate of protein synthesis of 14 g/kg.d and protein breakdown of 12 g/kg.d in five VLBW fed a formula diet. The elevated energy expenditure of the very low birth weight infant seems to be related to its rapid rate of weight gain which is accompanied by a high rate of body protein synthesis. More than 20% of the total energy expenditure of the VLBW infants was accounted for by whole body protein synthesis

Monitoring falls in gastric cancer mortality in Europe

We have considered trends in age-standardized mortality from gastric cancer in 25 individual European countries, as well as in the European Union (EU) as a whole, in six selected central-eastern European countries and in the Russian Federation over the period 1950-1999. Steady and persisting falls in rates were observed, and the fall between 1980 and 1999 was approximately 50% in the EU, 45% in eastern Europe and 40% in Russia. However, the declines were greater in Russia and eastern Europe, since rates were much higher, in absolute terms. Joinpoint regression analysis indicated that the falls were proportionally greater in the last decade for men (-3.83% per year in the EU) and in the last 25 years for women (-3.67% per year in the EU) than in previous calendar years. Moreover, steady declines in gastric cancer mortality were observed in the middle-aged and the young population as well, suggesting that they are likely to persist in the near future. In terms of number of deaths avoided, however, the impact of the decline in gastric cancer mortality will be smaller, particularly in the EU. [Authors]]]> Mortality ; Stomach Neoplasms ; Europe ; Russia https://serval.unil.ch/resource/serval:BIB_9936EEFA2B5C.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_9936EEFA2B5C8 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_9936EEFA2B5C8 info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/openAccess Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer application/pdf oai:serval.unil.ch:BIB_99293AD0C5E5 2022-05-07T01:23:27Z <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_99293AD0C5E5 Training During the COVID-19 Lockdown: Knowledge, Beliefs, and Practices of 12,526 Athletes from 142 Countries and Six Continents. info:doi:10.1007/s40279-021-01573-z info:eu-repo/semantics/altIdentifier/doi/10.1007/s40279-021-01573-z info:eu-repo/semantics/altIdentifier/pmid/34687439 Washif, J.A. Farooq, A. Krug, I. Pyne, D.B. Verhagen, E. Taylor, L. Wong, D.P. Mujika, I. Cortis, C. Haddad, M. Ahmadian, O. Al Jufaili, M. Al-Horani, R.A. Al-Mohannadi, A.S. Aloui, A. Ammar, A. Arifi, F. Aziz, A.R. Batuev, M. Beaven, C.M. Beneke, R. Bici, A. Bishnoi, P. Bogwasi, L. Bok, D. Boukhris, O. Boullosa, D. Bragazzi, N. Brito, J. Cartagena, RPP Chaouachi, A. Cheung, S.S. Chtourou, H. Cosma, G. Debevec, T. DeLang, M.D. Dellal, A. Dönmez, G. Driss, T. Peña Duque, J.D. Eirale, C. Elloumi, M. Foster, C. Franchini, E. Fusco, A. Galy, O. Gastin, P.B. Gill, N. Girard, O. Gregov, C. Halson, S. Hammouda, O. Hanzlíková, I. Hassanmirzaei, B. Haugen, T. Hébert-Losier, K. Muñoz Helú, H. Herrera-Valenzuela, T. Hettinga, F.J. Holtzhausen, L. Hue, O. Dello Iacono, A. Ihalainen, J.K. James, C. Janse van Rensburg, D.C. Joseph, S. Kamoun, K. Khaled, M. Khalladi, K. Kim, K.J. Kok, L.Y. MacMillan, L. Mataruna-Dos-Santos, L.J. Matsunaga, R. Memishi, S. Millet, G.P. Moussa-Chamari, I. Musa, D.I. Nguyen, HMT Nikolaidis, P.T. Owen, A. Padulo, J. Pagaduan, J.C. Perera, N.P. Pérez-Gómez, J. Pillay, L. Popa, A. Pudasaini, A. Rabbani, A. Rahayu, T. Romdhani, M. Salamh, P. Sarkar, A.S. Schillinger, A. Seiler, S. Setyawati, H. Shrestha, N. Suraya, F. Tabben, M. Trabelsi, K. Urhausen, A. Valtonen, M. Weber, J. Whiteley, R. Zrane, A. Zerguini, Y. Zmijewski, P. Sandbakk, Ø. Ben Saad, H. Chamari, K. info:eu-repo/semantics/article article 2022-04 Sports medicine, vol. 52, no. 4, pp. 933-948 info:eu-repo/semantics/altIdentifier/eissn/1179-2035 urn:issn:0112-1642 <![CDATA[Our objective was to explore the training-related knowledge, beliefs, and practices of athletes and the influence of lockdowns in response to the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Athletes (n = 12,526, comprising 13% world class, 21% international, 36% national, 24% state, and 6% recreational) completed an online survey that was available from 17 May to 5 July 2020 and explored their training behaviors (training knowledge, beliefs/attitudes, and practices), including specific questions on their training intensity, frequency, and session duration before and during lockdown (March-June 2020). Overall, 85% of athletes wanted to "maintain training," and 79% disagreed with the statement that it is "okay to not train during lockdown," with a greater prevalence for both in higher-level athletes. In total, 60% of athletes considered "coaching by correspondence (remote coaching)" to be sufficient (highest amongst world-class athletes). During lockdown, &lt; 40% were able to maintain sport-specific training (e.g., long endurance [39%], interval training [35%], weightlifting [33%], plyometric exercise [30%]) at pre-lockdown levels (higher among world-class, international, and national athletes), with most (83%) training for "general fitness and health maintenance" during lockdown. Athletes trained alone (80%) and focused on bodyweight (65%) and cardiovascular (59%) exercise/training during lockdown. Compared with before lockdown, most athletes reported reduced training frequency (from between five and seven sessions per week to four or fewer), shorter training sessions (from ≥ 60 to &lt; 60 min), and lower sport-specific intensity (~ 38% reduction), irrespective of athlete classification. COVID-19-related lockdowns saw marked reductions in athletic training specificity, intensity, frequency, and duration, with notable within-sample differences (by athlete classification). Higher classification athletes had the strongest desire to "maintain" training and the greatest opposition to "not training" during lockdowns. These higher classification athletes retained training specificity to a greater degree than others, probably because of preferential access to limited training resources. More higher classification athletes considered "coaching by correspondence" as sufficient than did lower classification athletes. These lockdown-mediated changes in training were not conducive to maintenance or progression of athletes' physical capacities and were also likely detrimental to athletes' mental health. These data can be used by policy makers, athletes, and their multidisciplinary teams to modulate their practice, with a degree of individualization, in the current and continued pandemic-related scenario. Furthermore, the data may drive training-related educational resources for athletes and their multidisciplinary teams. Such upskilling would provide athletes with evidence to inform their training modifications in response to germane situations (e.g., COVID related, injury, and illness)