Dans l'oeil du cyclotron: quand la haute technologie défie le cancer

Cet ouvrage retrace l'histoire du cyclotron Medicyc, ce pionnier relativement méconnu de la protonthérapie en France qui permit à Nice le premier traitement d'un mélanome de l'oeil au centre Antoine Lacassagne. Fruit d'une étroite collaboration entre l'ingénieur et le médecin et, dès l'origine, dévolu à la radiothérapie des tumeurs et à la production de radio-isotopes médicaux. Aujourd'hui, quelques vingt-cinq ans plus tard, cette protonthérapie connaît un essor considérable dans le monde

Réhabilitation du laryngectomisé (intérêt de l'échangeur de chaleur et d'humidité Provox®, à partir d'un essai randomisé multicentrique)

NICE-BU Médecine Odontologie (060882102) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Current Therapeutic Strategies in Patients with Oropharyngeal Squamous Cell Carcinoma: Impact of the Tumor HPV Status

Since there is no published randomized study comparing surgical and non-surgical therapeutic strategies in patients with oropharyngeal squamous cell carcinoma (OPSCC), the therapeutic management of these patients remains highly controversial. While human papillomavirus (HPV)-positive and HPV-negative OPSCC are now recognized as two distinct diseases with different epidemiological, biological, and clinical characteristics, the impact of HPV status on the management of OPSCC patients is still unclear. In this review, we analyze the current therapeutic options in patients with OPSCC, highlighting the most recent advances in surgical and non-surgical therapies, and we discuss the impact of HPV status on the therapeutic strategy

A multicentric study of the G.E.T.T.E.C. (Groupe d’Etudes des Tumeurs de la Tête et du Cou) about 408 clinically complete responders after neo-adjuvant chemotherapy for head and neck carcinomas

info:eu-repo/semantics/publishe

A randomized EORTC study on the effect of preoperative polychemotherapy in pyriform sinus carcinoma treated by pharyngolaryngectomy and irradiation. Results from 5 to 10 years

SCOPUS: cp.jinfo:eu-repo/semantics/publishe

Evolution and predictive factors of quality of life in patients undergoing oncologic surgery for head and neck cancer: A prospective multicentric study

International audienc

Dentalmaps: Automatic dental delineation for radiotherapy planning in head-and-neck cancer

Purpose: To propose an automatic atlas-based segmentation framework of the dental structures, called Dentalmaps, and to assess its accuracy and relevance to guide dental care in the context of intensity-modulated radiotherapy. Methods and Materials: A multi-atlas-based segmentation, less sensitive to artifacts than previously published head-and-neck segmentation methods, was used. The manual segmentations of a 21-patient database were first deformed onto the query using nonlinear registrations with the training images and then fused to estimate the consensus segmentation of the query. Results: The framework was evaluated with a leave-one-out protocol. The maximum doses estimated using manual contours were considered as ground truth and compared with the maximum doses estimated using automatic contours. The dose estimation error was within 2-Gy accuracy in 75% of cases (with a median of 0.9 Gy), whereas it was within 2-Gy accuracy in 30% of cases only with the visual estimation method without any contour, which is the routine practice procedure. Conclusions: Dose estimates using this framework were more accurate than visual estimates without dental contour. Dentalmaps represents a useful documentation and communication tool between radiation oncologists and dentists in routine practice. Prospective multicenter assessment is underway on patients extrinsic to the database. © 2012 Elsevier Inc