443 research outputs found
Can you trust what you hear? Concurrent misinformation affects recall memory and judgments of guilt.
n most misinformation studies, participants are exposed to a to-be-remembered event, and then subsequently given misinformation in textual form. This misinformation impacts on peopleâs ability to accurately report the initial event. In this paper, we present two experiments that explored a different approach to presenting misinformation. In the context of a murder suspect, the to-be-remembered event was audio of a police interview, whilst the misinformation was co-presented as subtitles with some words being different to, and more incriminating than, those that were actually said. We refer to this as concurrent misinformation. In Experiment 1, concurrent misinformation was inappropriately reported in a cued-recall test, and inflated participantsâ ratings of how incriminating the audio was. Experiment 2 attempted to employ warnings to mitigate the influence of concurrent misinformation. Warnings after the to-be-remembered event had no effect, whilst warnings before the event reduced the effect of concurrent misinformation for a sub-set of participants. Participants that noticed the discrepancy between the audio and the sub-titles were also less likely to judge the audio as incriminating. These results were considered in relation to existing theories underlying the misinformation effect, as well as the implication for the use of audio and text in applied contexts
The Effect of Software Team Personality Composition on Learning and Performance: Making the Dream Team
Optimizing work team composition in organizational and educational environments is an important task toward maximizing performance. Social science research has revealed that personality trait composition influences team cohesion and performance. However, this research has not been well-adapted into the IS context. In addition, prior research demonstrates how individual personality traits impact teams, but fails to appropriately characterize overall team personality composition. We expand this research by 1) characterizing holistic personality compositions, and 2) examining team learning in addition to performance in the IS context. We draw from theory on team performance and Big 5 trait composition. Results demonstrate that teams comprised of homogenous versus heterogeneous personality compositions differ in their performance and learning. The primary implication of this research is that teams can benefit from a priori personality measurements and directed composition. Initially, optimal learning and effectiveness comes from homogenous teams. However, this may change over time
The Impact of a Poverty Reduction Intervention on Infant Brain Activity
Early childhood poverty is a risk factor for lower school achievement, reduced earnings, and poorer health, and has been associated with differences in brain structure and function. Whether poverty causes differences in neurodevelopment, or is merely associated with factors that cause such differences, remains unclear. Here, we report estimates of the causal impact of a poverty reduction intervention on brain activity in the first year of life. We draw data from a subsample of the Baby's First Years study, which recruited 1,000 diverse low-income motherâinfant dyads. Shortly after giving birth, mothers were randomized to receive either a large or nominal monthly unconditional cash gift. Infant brain activity was assessed at approximately 1 y of age in the child's home, using resting electroencephalography (EEG; n = 435). We hypothesized that infants in the high-cash gift group would have greater EEG power in the mid- to high-frequency bands and reduced power in a low-frequency band compared with infants in the low-cash gift group. Indeed, infants in the high-cash gift group showed more power in high-frequency bands. Effect sizes were similar in magnitude to many scalable education interventions, although the significance of estimates varied with the analytic specification. In sum, using a rigorous randomized design, we provide evidence that giving monthly unconditional cash transfers to mothers experiencing poverty in the first year of their children's lives may change infant brain activity. Such changes reflect neuroplasticity and environmental adaptation and display a pattern that has been associated with the development of subsequent cognitive skills
Plasmapheresis to remove amyloid fibrin(ogen) particles for treating the postâCOVIDâ19 condition
Background
The postâCOVIDâ19 condition (PCC) consists of a wide array of symptoms including fatigue and impaired daily living. People seek a wide variety of approaches to help them recover.
A new belief, arising from a few laboratory studies, is that 'microclots' cause the symptoms of PCC. This belief has been extended outside these studies, suggesting that to recover people need plasmapheresis (an expensive process where blood is filtered outside the body). We appraised the laboratory studies, and it was clear that the term 'microclots' is incorrect to describe the phenomenon being described. The particles are amyloid and include fibrin(ogen); amyloid is not a part of a thrombus which is a mix of fibrin mesh and platelets. Initial acute COVIDâ19 infection is associated with clotting abnormalities; this review concerns amyloid fibrin(ogen) particles in PCC only.
We have reported here our appraisal of laboratory studies investigating the presence of amyloid fibrin(ogen) particles in PCC, and of evidence that plasmapheresis may be an effective therapy to remove amyloid fibrin(ogen) particles for treating PCC.
Objectives
Laboratory studies review
To summarize and appraise the research reports on amyloid fibrin(ogen) particles related to PCC.
Randomized controlled trials review
To assess the evidence of the safety and efficacy of plasmapheresis to remove amyloid fibrin(ogen) particles in individuals with PCC from randomized controlled trials.
Search methods
Laboratory studies review
We searched for all relevant laboratory studies up to 27 October 2022 using a comprehensive search strategy which included the search terms âCOVIDâ, âamyloidâ, âfibrinâ, âfibrinogenâ.
Randomized controlled trials review
We searched the following databases on 21 October 2022: Cochrane COVIDâ19 Study Register; MEDLINE (Ovid); Embase (Ovid); and BIOSIS Previews (Web of Science). We also searched the WHO International Clinical Trials Registry Platform and ClinicalTrials.gov for trials in progress.
Selection criteria
Laboratory studies review
Laboratory studies that investigate the presence of amyloid fibrin(ogen) particles in plasma samples from patients with PCC were eligible. This included studies with or without controls.
Randomized controlled trials review
Studies were eligible if they were of randomized controlled design and investigated the effectiveness or safety of plasmapheresis for removing amyloid fibrin(ogen) particles for treating PCC.
Data collection and analysis
Two review authors applied study inclusion criteria to identify eligible studies and extracted data.
Laboratory studies review
We assessed the risk of bias of included studies using preâdeveloped methods for laboratory studies. We planned to perform synthesis without metaâanalysis (SWiM) as described in our protocol.
Randomized controlled trials review
We planned that if we identified any eligible studies, we would assess risk of bias and report results with 95% confidence intervals. The primary outcome was recovery, measured using the PostâCOVIDâ19 Functional Status Scale (absence of symptoms related to the illness, ability to do usual daily activities, and a return to a previous state of health and mind).
Main results
Laboratory studies review
We identified five laboratory studies. Amyloid fibrin(ogen) particles were identified in participants across all studies, including those with PCC, healthy individuals, and those with diabetes. The results of three studies were based on visual images of amyloid fibrin(ogen) particles, which did not quantify the amount or size of the particles identified. Formal risk of bias assessment showed concerns in how the studies were conducted and reported. This means the results were insufficient to support the belief that amyloid fibrin(ogen) particles are associated with PCC, or to determine whether there is a difference in the amount or size of amyloid fibrin(ogen) particles in the plasma of people with PCC compared to healthy controls.
Randomized controlled trials review
We identified no trials meeting our inclusion criteria.
Authors' conclusions
In the absence of reliable research showing that amyloid fibrin(ogen) particles contribute to the pathophysiology of PCC, there is no rationale for plasmapheresis to remove amyloid fibrin(ogen) particles in PCC. Plasmapheresis for this indication should not be used outside the context of a wellâconducted randomized controlled trial
Evaluating the End-User Experience of Private Browsing Mode
Nowadays, all major web browsers have a private browsing mode. However, the
mode's benefits and limitations are not particularly understood. Through the
use of survey studies, prior work has found that most users are either unaware
of private browsing or do not use it. Further, those who do use private
browsing generally have misconceptions about what protection it provides.
However, prior work has not investigated \emph{why} users misunderstand the
benefits and limitations of private browsing. In this work, we do so by
designing and conducting a three-part study: (1) an analytical approach
combining cognitive walkthrough and heuristic evaluation to inspect the user
interface of private mode in different browsers; (2) a qualitative,
interview-based study to explore users' mental models of private browsing and
its security goals; (3) a participatory design study to investigate why
existing browser disclosures, the in-browser explanations of private browsing
mode, do not communicate the security goals of private browsing to users.
Participants critiqued the browser disclosures of three web browsers: Brave,
Firefox, and Google Chrome, and then designed new ones. We find that the user
interface of private mode in different web browsers violates several
well-established design guidelines and heuristics. Further, most participants
had incorrect mental models of private browsing, influencing their
understanding and usage of private mode. Additionally, we find that existing
browser disclosures are not only vague, but also misleading. None of the three
studied browser disclosures communicates or explains the primary security goal
of private browsing. Drawing from the results of our user study, we extract a
set of design recommendations that we encourage browser designers to validate,
in order to design more effective and informative browser disclosures related
to private mode
Implementation of Medication Event Reminder Monitors among patients diagnosed with drug susceptible tuberculosis in rural Viet Nam: A qualitative study.
BACKGROUND: Despite the criticality of adherence to tuberculosis treatment, there is paucity of rigorous experimental research exploring the efficacy of interventions to promote adherence and a greater lack of inquiry addressing the integral role of adherence behaviour. The aim of this formative study was to examine the way in which the Wisepill evriMED Medication Event Reminder Monitor (MERM) was used among outpatients with drug susceptible pulmonary tuberculosis. METHODS: In depth interviews were conducted with 20 outpatients receiving treatment from two public healthcare facilities in Thanh Hoa, a rural province in northern Viet Nam. Patients had been enrolled in a randomized controlled trial evaluating the effect of using the MERM device upon adherence for between 1-3 months. The control group used the device without an alert, while the intervention group used the device with a daily alert and scheduled dosing history review. FINDINGS: All 20 patients interviewed were supportive of using the MERM device. Those able to be at home at the time that their treatment was due (50%) used the device as intended. Patients who worked all reported separating the time when the box was opened from the time at which they ingested their medication. Patients expressed fidelity to the prescribed medication taking time and concerns regarding the portability of the device. Limitations of the study surround the inclusion of a small sample population that did not experience factors that further compromise adherence. CONCLUSIONS: Data recorded by the box did not always accurately reflect usage patterns. The alert in the intervention arm was able to support adherence only in patients who did not work while completing their treatment. MERM implementation can be improved by better aligning prescriber instructions with patients' daily routines, and increasing the use of adherence data to guide adherence support practices. Healthcare staff need to be aware of potential barriers to optimal use of MERM devices. A rigorous qualitative approach to formative assessment is essential to inform the scale up of new digital technologies
Implementation of Medication Event Reminder Monitors among patients diagnosed with drug susceptible tuberculosis in rural Viet Nam: A qualitative study.
BACKGROUND: Despite the criticality of adherence to tuberculosis treatment, there is paucity of rigorous experimental research exploring the efficacy of interventions to promote adherence and a greater lack of inquiry addressing the integral role of adherence behaviour. The aim of this formative study was to examine the way in which the Wisepill evriMED Medication Event Reminder Monitor (MERM) was used among outpatients with drug susceptible pulmonary tuberculosis. METHODS: In depth interviews were conducted with 20 outpatients receiving treatment from two public healthcare facilities in Thanh Hoa, a rural province in northern Viet Nam. Patients had been enrolled in a randomized controlled trial evaluating the effect of using the MERM device upon adherence for between 1-3 months. The control group used the device without an alert, while the intervention group used the device with a daily alert and scheduled dosing history review. FINDINGS: All 20 patients interviewed were supportive of using the MERM device. Those able to be at home at the time that their treatment was due (50%) used the device as intended. Patients who worked all reported separating the time when the box was opened from the time at which they ingested their medication. Patients expressed fidelity to the prescribed medication taking time and concerns regarding the portability of the device. Limitations of the study surround the inclusion of a small sample population that did not experience factors that further compromise adherence. CONCLUSIONS: Data recorded by the box did not always accurately reflect usage patterns. The alert in the intervention arm was able to support adherence only in patients who did not work while completing their treatment. MERM implementation can be improved by better aligning prescriber instructions with patients' daily routines, and increasing the use of adherence data to guide adherence support practices. Healthcare staff need to be aware of potential barriers to optimal use of MERM devices. A rigorous qualitative approach to formative assessment is essential to inform the scale up of new digital technologies
Earnings Management: The Effect of Ex Ante Earnings Expectations
Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline
Reverberation Mapping of the Kepler-Field AGN KA1858+4850
KA1858+4850 is a narrow-line Seyfert 1 galaxy at redshift 0.078 and is among
the brightest active galaxies monitored by the Kepler mission. We have carried
out a reverberation mapping campaign designed to measure the broad-line region
size and estimate the mass of the black hole in this galaxy. We obtained 74
epochs of spectroscopic data using the Kast Spectrograph at the Lick 3-m
telescope from February to November of 2012, and obtained complementary V-band
images from five other ground-based telescopes. We measured the H-beta light
curve lag with respect to the V-band continuum light curve using both
cross-correlation techniques (CCF) and continuum light curve variability
modeling with the JAVELIN method, and found rest-frame lags of lag_CCF = 13.53
(+2.03, -2.32) days and lag_JAVELIN = 13.15 (+1.08, -1.00) days. The H-beta
root-mean-square line profile has a width of sigma_line = 770 +/- 49 km/s.
Combining these two results and assuming a virial scale factor of f = 5.13, we
obtained a virial estimate of M_BH = 8.06 (+1.59, -1.72) x 10^6 M_sun for the
mass of the central black hole and an Eddington ratio of L/L_Edd ~ 0.2. We also
obtained consistent but slightly shorter emission-line lags with respect to the
Kepler light curve. Thanks to the Kepler mission, the light curve of
KA1858+4850 has among the highest cadences and signal-to-noise ratios ever
measured for an active galactic nucleus; thus, our black hole mass measurement
will serve as a reference point for relations between black hole mass and
continuum variability characteristics in active galactic nuclei
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