435 research outputs found
A Comment on "The Far Future of Exoplanet Direct Characterization" - the Case for Interstellar Space Probes
Following on from ideas presented in a recent paper by Schneider et al.
(2010) on "The Far Future of Exoplanet Direct Characterization", I argue that
they have exaggerated the technical obstacles to performing such 'direct
characterization' by means of fast (order 0.1c) interstellar space probes. A
brief summary of rapid interstellar spaceflight concepts that may be found in
the literature is presented. I argue that the presence of interstellar dust
grains, while certainly something which will need to be allowed for in
interstellar vehicle design, is unlikely to be the kind of 'show stopper'
suggested by Schneider et al. Astrobiology as a discipline would be a major
beneficiary of developing an interstellar spaceflight capability, albeit in the
longer term, and I argue that astrobiologists should keep an open mind to the
possibilities.Comment: Accepted for publication in Astrobiolog
Postoperative outcome of ambulatory dogs with intervertebral disc extrusion causing incontinence and/or tail dysfunction:18 cases (2010-2020)
OBJECTIVES: To assess the recovery of urinary continence, faecal continence and tail function in ambulatory dogs with caudal lumbar intervertebral disc extrusion and to explore clinical factors that may be associated with recovery. MATERIALS AND METHODS: Medical records from January 2010 to December 2020 were searched to identify ambulatory dogs undergoing surgical treatment for a caudal lumbar intervertebral disc extrusion causing urinary incontinence, faecal incontinence and/or tail dysfunction. Signalment, history, presenting clinical signs, neurological examination findings, diagnostic test results, treatment and outcome were recorded for all dogs. RESULTS: Eighteen dogs with caudal lumbar intervertebral disc extrusion causing tail dysfunction, urinary and/or faecal incontinence were included. Urinary continence was recovered in 12 (86%) of 14 affected dogs, faecal continence recovered in nine (90%) of 10 affected dogs and tail function recovered in 13 (87%) of 15 affected dogs. Loss of tail nociception was recorded in three dogs on presentation; two made a full recovery and one showed mild persistent tail paresis. CLINICAL SIGNIFICANCE: The prognosis for functional recovery of urinary continence, faecal continence and tail function in ambulatory dogs with caudal lumbar intervertebral disc extrusion following surgical treatment is good. Larger studies are needed to identify prognostic factors associated with failure of recovery
Clinical presentation, diagnostic findings and outcome of dogs undergoing surgical resection for intracranial meningioma: 101 dogs
Background: Meningioma is the most common primary brain neoplasm in dogs. Further information is required regarding the expected long-term prognosis of dogs following the surgical resection of an intracranial meningioma together with the influence of adjunctive therapies. Whilst there have been several studies reporting the long-term outcome of intracranial meningioma resection following surgery alone, surgery with the use of an ultrasonic aspirator, surgery combined with radiotherapy and surgery combined with the addition of hydroxyurea, it is currently unclear which type of adjunctive therapy is associated with the most favourable outcomes. The objective of this study is to describe the presentation and outcome of dogs undergoing surgery for the resection of an intracranial meningioma and the effect of clinical factors, adjunctive therapies and meningioma histopathological subtype on the long-term outcome. Results: A hundred and one dogs that had intracranial surgery for meningioma resection were investigated from four referral centres. 94% of dogs survived to hospital discharge with a median survival time of 386 days. Approximately 50% of dogs survived for less than a year, 25% survived between 1 and 2 years, 15% survived between 2 and 3 years and 10% survived for greater than 3 years following discharge from hospital. One or more adjunctive therapies were used in 75 dogs and the analysis of the data did not reveal a clear benefit of a specific type of adjunctive therapy. Those dogs that had a transfrontal approach had a significantly reduced survival time (MST 184 days) compared to those dogs that had a rostrotentorial approach (MST 646 days; p < 0.05). There was no association between meningioma subtype and survival time. Conclusions: This study did not identify a clear benefit of a specific type of adjunctive therapy on the survival time. Dogs that had a transfrontal approach had a significantly reduced survival time. Intracranial surgery for meningioma resection offers an excellent prognosis for survival to discharge from hospital with a median long term survival time of 386 days
Removing non-stationary, non-harmonic external interference from gravitational wave interferometer data
We describe a procedure to identify and remove a class of non-stationary and
non-harmonic interference lines from gravitational wave interferometer data.
These lines appear to be associated with the external electricity main
supply, but their amplitudes are non-stationary and they do not appear at
harmonics of the fundamental supply frequency. We find an empirical model able
to represent coherently all the non-harmonic lines we have found in the power
spectrum, in terms of an assumed reference signal of the primary supply input
signal. If this signal is not available then it can be reconstructed from the
same data by making use of the coherent line removal algorithm that we have
described elsewhere. All these lines are broadened by frequency changes of the
supply signal, and they corrupt significant frequency ranges of the power
spectrum. The physical process that generates this interference is so far
unknown, but it is highly non-linear and non-stationary. Using our model, we
cancel the interference in the time domain by an adaptive procedure that should
work regardless of the source of the primary interference. We have applied the
method to laser interferometer data from the Glasgow prototype detector, where
all the features we describe in this paper were observed. The algorithm has
been tuned in such a way that the entire series of wide lines corresponding to
the electrical interference are removed, leaving the spectrum clean enough to
detect signals previously masked by them. Single-line signals buried in the
interference can be recovered with at least 75 % of their original signal
amplitude.Comment: 14 pages, 5 figures, Revtex, psfi
Focused Solar Ablation: A Nanosat-Based Method for Active Removal of Space Debris
A novel concept for the active removal of space debris using solar power is proposed. Focused solar ablation is an in-space propulsion concept based on using concentrator mirrors on nanosats and using the solar power to evaporate material from the debris to produce deceleration thrust thereby providing the âV necessary to deorbit. An energy balance is used along with free-molecular effusion theory to estimate the thrust produced by the concept and the corresponding deorbit times for an aluminum debris masses of 10 kg and 0.27 kg for various concentrator mirror areas and the diameter of the spot on which the solar power is concentrated. The analysis shows that the deorbit times of a few hours for both masses showing that the method is attractive for active space debris removal. Experiments performed using electron beams to evaporate aluminum in a vacuum chamber show that the method is also practically feasible to deorbit space debris using solar power available in low earth orbit (LEO)
Survey of highly non-Keplerian orbits with low-thrust propulsion
Celestial mechanics has traditionally been concerned with orbital motion under the action of a conservative gravitational potential. In particular, the inverse square gravitational force due to the potential of a uniform, spherical mass leads to a family of conic section orbits, as determined by Isaac Newton, who showed that Keplerâs laws were derivable from his theory of gravitation. While orbital motion under the action of a conservative gravitational potential leads to an array of problems with often complex and interesting solutions, the addition of non-conservative forces offers new avenues of investigation. In particular, non-conservative forces lead to a rich diversity of problems associated with the existence, stability and control of families of highly non-Keplerian orbits generated by a gravitational potential and a non-conservative force. Highly non-Keplerian orbits can potentially have a broad range of practical applications across a number of different disciplines. This review aims to summarize the combined wealth of literature concerned with the dynamics, stability and control of highly non-Keplerian orbits for various low thrust propulsion devices, and to demonstrate some of these potential applications
Centrally-administered nociceptin/orphanin FQ (N/OFQ) evokes bradycardia, hypotension and diuresis in mice via activation of central N/OFQ peptide (NOP) receptors
Aggravation by Paroxetine, A Selective Serotonin Re-Uptake Inhibitor, of Antral Lesions Generated by Nonsteroidal Anti-inflammatory Drugs in Rats
Detectability of gravitational wave events by spherical resonant-mass antennas
We have calculated signal-to-noise ratios for eight spherical resonant-mass
antennas interacting with gravitational radiation from inspiralling and
coalescing binary neutron stars and from the dynamical and secular bar-mode
instability of a rapidly rotating star. We find that by using technology that
could be available in the next several years, spherical antennas can detect
neutron star inspiral and coalescence at a distance of 15 Mpc and the dynamical
bar-mode instability at a distance of 2 Mpc.Comment: 39 pages, 4 EPS Figures, some additional SNRs for secular
instabilities, some changes to LIGO SNRs, Appendix added on the asymptotic
expansion of energy sensitivity, corrected supernova rates. Results available
at http://www.physics.umd.edu/rgroups/gen_rel_exp/snr.html Submitted to Phys.
Rev.
Incorporating the geometry of dispersal and migration to understand spatial patterns of species distributions
Dispersal and migration can be important drivers of species distributions. Because the paths followed by individuals of many species are curvilinear, spatial statistical models based on rectilinear coordinates systems would fail to predict population connectivity or the ecological consequences of migration or species invasions. I propose that we view migration/dispersal as if organisms were moving along curvilinear geometrical objects called smooth manifolds. In that view, the curvilinear pathways become the âshortest realised pathsâ arising from the necessity to minimise mortality risks and energy costs. One can then define curvilinear coordinate systems on such manifolds. I describe a procedure to incorporate manifolds and define appropriate coordinate systems, with focus on trajectories (1D manifolds), as parts of mechanistic ecological models. I show how a statistical method, known as âmanifold learningâ, enables one to define the manifold and the appropriate coordinate systems needed to calculate population connectivity or study the effects of migrations (e.g. in aquatic invertebrates, fish, insects and birds). This approach may help in the design of networks of protected areas, in studying the consequences of invasion, range expansions, or transfer of parasites/diseases. Overall, a geometrical view to animal movement gives a novel perspective to the understanding of the ecological role of dispersal and migration
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