The zwitterion 1-butylimidazolium-3- (n-butanesulfonate)

The mol&shy;ecule of the title compound, C11H20N2O3S, contains a positively charged imidazolium head group and a negatively charged sulfonate tethered together by a four-carbon chain. There is weak intermolecular hydrogen bonding within the structure between the sulfonate O atoms and the H atoms of the imidazolium ring. The sulfonate group causes a twisting of the butyl chain and a decrease in the dihedral angle between the second and third carbon chain compared to the unsubstituted butyl group.<br /

2,2,7-Trichloro-3,4-dihydro­naphthalen-1(2H)-one

The title compound, C10H7Cl3O, obtained as a major byproduct from a classical Schmidt reaction. The cyclohexyl ring is distorted from a classical chair conformation, as observed for monocyclic analogues, presumably due to conjugation of the planar annulated benzo ring and the ketone group (r.m.s. deviation 0.024 Å). There are no significant intermolecular interactions

Di-μ2-methoxo-bis­{[μ-3,10,18,25-tetra­aza­penta­cyclo­[17.4.4.3.1.1]triconta-1(31),2,4(9),5,7,10,12,14,16(32),17,19(24),20,22,25,27,29-hexa­deca­ene-31,32-diolato]dizinc(II)} bis­(perchlorate) N,N-dimethyl­formamide disolvate

The title compound, [Zn4(C28H18N4O2)2(CH3O)2](ClO4)2·2C3H7NO, is a C2 symmetric tetra­nuclear zinc(II) complex comprised of two [Zn2 L]2+ units bridged by a pair of μ2-OMe ligands (where L is the doubly-deprotonated form of the macrocyclic dinucleating ligand derived from the [2 + 2] Schiff base condensation between 2-hy­droxy­benzene-1,3-dicarbaldehyde and 1,2-diamino­benzene). Each ZnII atom has a distorted square-pyramidal coordination geometry and the Zn4(μ-OMe)2 unit lies in the cleft formed by two distinctly bent Schiff base ligands. The observed mol­ecular shape is supported by an intra­molecular π–π inter­action between one of the phenolate rings on each of the two ligands [centroid–centroid distance = 3.491 (5) Å]. The methyl groups of the solvent molecule are disordered over two sets of sites in a 0.6:0.4 ratio

8-Chloro-5-(4-phenethylpiperazin-1-­yl)pyrido[2,3-b][1,5]benzoxazepine

As part of an anti­psychotic drug discovery program, we report the crystal structure of the title compound, C24H23ClN4O. The mol­ecule has a tricyclic framework with a characteristic buckled V-shaped pyridobenzoxazepine unit, with the central seven-membered heterocycle in a boat configuration. The piperazine ring displays a chair conformation with the 2-phenyl-ethyl substituent assuming an equatorial orientation. There are two crystallographically independent, but virtually identical, mol­ecules in the asymmetric unit

Di-tert-butyl N-[2,6-bis­(methoxy­meth­oxy)phen­yl]imino­diacetate

The title mol­ecule, C20H31NO8, has pseudo-C2 symmetry about the C—N bond, with the bis­(tert-butoxy­carbon­yl)amino group twisted from the benzene ring plane by ca 60° and the bulky tert-butoxy­carbonyl (Boc) groups are orientated away from the substituted aniline group. As part of an anti­bacterial drug discovery programme furnishing analogues of platensimycin, we unexpectedly synthesized the bis-Boc-protected aniline

Participation in physical play and leisure : developing a theory- and evidence-based intervention for children with motor impairments

Peer reviewedPublisher PD

Shared leadership and group identification in healthcare: : The leadership beliefs of clinicians working in interprofessional teams

This is an Accepted Manuscript of an article published by Taylor & Francis in Journal of Interprofessional Care on 28 February 2017, available online: http://www.tandfonline.com/doi/full/10.1080/13561820.2017.1280005.Despite the proposed benefits of applying shared and distributed leadership models in healthcare, few studies have explored the leadership beliefs of clinicians and ascertained whether differences exist between professions. The current paper aims to address these gaps and additionally, examine whether clinicians’ leadership beliefs are associated with the strength of their professional and team identifications. An online survey was responded to by 229 healthcare workers from community interprofessional teams in mental health settings across the East of England. No differences emerged between professional groups in their leadership beliefs; all professions reported a high level of agreement with shared leadership. A positive association emerged between professional identification and shared leadership i.e. participants who expressed the strongest level of profession identification also reported the greatest agreement with shared leadership. The same association was demonstrated for team identification and shared leadership. The findings highlight the important link between group identification and leadership beliefs, suggesting that strategies that promote strong professional and team identifications in interprofessional teams are likely to be conducive to clinicians supporting principles of shared leadership. Future research is needed to strengthen this link and examine the leadership practices of healthcare workers.Peer reviewe