The Formaldehyde Masers in Sgr B2: Very Long Baseline Array and Very Large Array Observations

Observations of two of the formaldehyde (H2CO) masers (A and D) in Sgr B2 using the VLBA+Y27 (resolution ~0.01") and the VLA (resolution ~9") are presented. The VLBA observations show compact sources (<10 milliarcseconds, <80 AU) with brightness temperatures >10^8 K. The maser sources are partially resolved in the VLBA observations. The flux densities in the VLBA observations are about 1/2 those of the VLA; and, the linewidths are about 2/3 of the VLA values. The applicability of a core-halo model for the emission distribution is demonstrated. Comparison with earlier H2CO absorption observations and with ammonia (NH3) observations suggests that H2CO masers form in shocked gas. Comparison of the integrated flux densities in current VLA observations with those in previous observations indicates that (1) most of the masers have varied in the past 20 years, and (2) intensity variations are typically less than a factor of two compared to the 20-year mean. No significant linear or circular polarization is detected with either instrument.Comment: 20 pages, 3 figures, 5 tables, accepted to Ap

Letter, 1940 June 12, from F. J. A. Forster to Carson Robison

1 page, Forster was the owners of Forster Music Publisher, Inc. He was a friend of Robison\u27s

Letter, 1940 June 17, from F. J. A. Forster to Carson Robison

1 page, Forster was the owners of Forster Music Publisher, Inc. He was a friend of Robison\u27s

Local availability and long-range trade: the worked stone assemblage

Inter disciplinary study of major excavation assemblage from Norse settlement site in Orkney. Combines methodological and typological developments with scientific discussion

A Search for H2CO 6cm Emission toward Young Stellar Objects III: VLA Observations

We report the results of our third survey for formaldehyde (H2CO) 6cm maser emission in the Galaxy. Using the Very Large Array, we detected two new H2CO maser sources (G23.01-0.41 and G25.83-0.18), thus increasing the sample of known H2CO maser regions in the Galaxy to seven. We review the characteristics of the G23.01-0.41 and G25.83-0.18 star forming regions. The H2CO masers in G23.01-0.41 and G25.83-0.18 share several properties with the other known H2CO masers, in particular, emission from rich maser environments and close proximity to very young massive stellar objects.Comment: Accepted for publication in the Astrophysical Journal Supplement Serie

The transient response of global-mean precipitation to increasing carbon dioxide levels

The transient response of global-mean precipitation to an increase in atmospheric carbon dioxide levels of 1% yr(-1) is investigated in 13 fully coupled atmosphere-ocean general circulation models (AOGCMs) and compared to a period of stabilization. During the period of stabilization, when carbon dioxide levels are held constant at twice their unperturbed level and the climate left to warm, precipitation increases at a rate of similar to 2.4% per unit of global-mean surface-air-temperature change in the AOGCMs. However, when carbon dioxide levels are increasing, precipitation increases at a smaller rate of similar to 1.5% per unit of global-mean surface-air-temperature change. This difference can be understood by decomposing the precipitation response into an increase from the response to the global surface-temperature increase (and the climate feedbacks it induces), and a fast atmospheric response to the carbon dioxide radiative forcing that acts to decrease precipitation. According to the multi-model mean, stabilizing atmospheric levels of carbon dioxide would lead to a greater rate of precipitation change per unit of global surface-temperature change

Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients

Purpose: Methotrexate administration is associated with frequent adverse neurological events during treatment for childhood acute lymphoblastic leukemia. Here, we present evidence to support the role of common drug interactions and low vitamin B12 levels in potentiating methotrexate neurotoxicity. Methods: We review the published evidence and highlight key potential drug interactions as well as present clinical evidence of severe methotrexate neurotoxicity in conjunction with nitrous oxide anesthesia and measurements of vitamin B12 levels among pediatric leukemia patients during therapy. Results: We describe a very plausible mechanism for methotrexate neurotoxicity in pediatric leukemia patients involving reduction in methionine and consequential disruption of myelin production. We provide evidence that a number of commonly prescribed drugs in pediatric leukemia management interact with the same folate biosynthetic pathways and/or reduce functional vitamin B12 levels and hence are likely to increase the toxicity of methotrexate in these patients. We also present a brief case study supporting out hypothesis that nitrous oxide contributes to methotrexate neurotoxicity and a nutritional study, showing that patients. Conclusions: Use of nitrous oxide in pediatric leukemia patients at the same time as methotrexate use should be avoided especially as many suitable alternative anesthetic agents exist. Clinicians should consider monitoring levels of vitamin B12 in patients suspected of having methotrexate- induced neurotoxic effects

Reply: Methotrexate neurotoxicity due to drug interactions: an inadequate folinic acid effect

No abstract available

Morphological analysis of the cm-wave continuum in the dark cloud LDN1622

The spectral energy distribution of the dark cloud LDN1622, as measured by Finkbeiner using WMAP data, drops above 30GHz and is suggestive of a Boltzmann cutoff in grain rotation frequencies, characteristic of spinning dust emission. LDN1622 is conspicuous in the 31 GHz image we obtained with the Cosmic Background Imager, which is the first cm-wave resolved image of a dark cloud. The 31GHz emission follows the emission traced by the four IRAS bands. The normalised cross-correlation of the 31 GHz image with the IRAS images is higher by 6.6sigma for the 12um and 25um bands than for the 60um and 100um bands: C(12+25) = 0.76+/-0.02 and C(60+100) = 0.64+/-0.01. The mid-IR -- cm-wave correlation in LDN 1622 is evidence for very small grain (VSG) or continuum emission at 26-36GHz from a hot molecular phase. In dark clouds and their photon-dominated regions (PDRs) the 12um and 25um emission is attributed to stochastic heating of the VSGs. The mid-IR and cm-wave dust emissions arise in a limb-brightened shell coincident with the PDR of LDN1622, where the incident UV radiation from the Ori OB1b association heats and charges the grains, as required for spinning dust.Comment: accepted for publication in ApJ - the complete article with uncompressed figures may be downloaded from http://www.das.uchile.cl/~simon/ftp/l1622.pd