Primary Subcutaneous B-cell Lymphoma : Case Report and Literature Review

Primary cutaneous B-cell lymphomas are defined as malignant B-cell proliferations presenting with cutaneous involvement alone and no evidence of extracutaneous manifestations when complete staging has been performed. It has been shown that the infiltrate in some cases could involve the underlying subcutaneous tissues, but primary localization in this compartment has been rarely reported. We describe here the case of a 53-year-old woman who noticed a nodular lesion on the left shoulder that rapidly enlarged in a few months. The histological and immunophenotypical features were compatible with a subcutaneous B-cell lymphoma. The tumoural mass was confined predominantly to the subcutaneous compartment, as confirmed by computed tomography. No other tumour localizations were found. Thus, primary B-cell lymphoma of the subcutis was diagnosed. We report a review of the literature indicating that B-cell lymphomas that are primarily localized to the subcutaneous tissue represent a very rare modality of presentation with a biological behaviour different from conventional cutaneous B-cell lymphoma

Life events and psychological distress in dermatologic disorders: psoriasis, chronic urticaria and fungal infections.

A consecutive unselected series of 60 in-patients suffering from dermatologic disorders (psoriasis, chronic urticaria and fungal infections of the skin) was examined. Twenty patients with each illness were included. Stressful life events immediately before illness onset, levels of psychological distress, and alexithymic traits were investigated. Patients with psoriasis and chronic urticaria were exposed to stressful life situations before disease onset and suffered from psychological distress (anxiety, depression, inadequacy) significantly more than those with fungal infections. Implications for psychosomatic research and treatment are discusse

[Chronic serologic false positivity for syphilis. Clinical and laboratory follow-up]

none6noneA. PESERICO STECCHINI NEGRI DE SALVI; FORNASA CV; BETTIN A; CIPRIANI R; BERTOLI P; BETTERLE CPESERICO STECCHINI NEGRI DE SALVI, Andrea; Fornasa, Cv; Bettin, A; Cipriani, R; Bertoli, P; Betterle, Corrad