2,025 research outputs found
Neural correlates of verbal feedback processing: an fMRI study employing overt speech
Speakers use external auditory feedback to monitor their own speech. Feedback distortion has been found to increase activity in the superior temporal areas. Using fMRI, the present study investigates the neural correlates of processing verbal feedback without distortion. In a blocked design, the following conditions were presented: (1) overt picture-naming, (2) overt picture-naming while pink noise was presented to mask external feedback, (3) covert picture-naming, (4) listening to the picture names (previously recorded from participants' own voices), and (5) listening to pink noise. The results show that auditory feedback processing involves a network of different areas related to general performance monitoring and speech-motor control. These include the cingulate cortex and the bilateral insula, supplementary motor area, bilateral motor areas, cerebellum, thalamus and basal ganglia. Our findings suggest that the anterior cingulate cortex, which is often implicated in error-processing and conflict-monitoring, is also engaged in ongoing speech monitoring. Furthermore, in the superior temporal gyrus, we found a reduced response to speaking under normal feedback conditions. This finding is interpreted in the framework of a forward model according to which, during speech production, the sensory consequence of the speech-motor act is predicted to attenuate the sensitivity of the auditory cortex. Hum Brain Mapp 2007. © 2007 Wiley-Liss, Inc
How learning to abstract shapes neural sound representations
The transformation of acoustic signals into abstract perceptual representations is the essence of the efficient and goal-directed neural processing of sounds in complex natural environments. While the human and animal auditory system is perfectly equipped to process the spectrotemporal sound features, adequate sound identification and categorization require neural sound representations that are invariant to irrelevant stimulus parameters. Crucially, what is relevant and irrelevant is not necessarily intrinsic to the physical stimulus structure but needs to be learned over time, often through integration of information from other senses. This review discusses the main principles underlying categorical sound perception with a special focus on the role of learning and neural plasticity. We examine the role of different neural structures along the auditory processing pathway in the formation of abstract sound representations with respect to hierarchical as well as dynamic and distributed processing models. Whereas most fMRI studies on categorical sound processing employed speech sounds, the emphasis of the current review lies on the contribution of empirical studies using natural or artificial sounds that enable separating acoustic and perceptual processing levels and avoid interference with existing category representations. Finally, we discuss the opportunities of modern analyses techniques such as multivariate pattern analysis (MVPA) in studying categorical sound representations. With their increased sensitivity to distributed activation changes—even in absence of changes in overall signal level—these analyses techniques provide a promising tool to reveal the neural underpinnings of perceptually invariant sound representations
Mechanical-physical experimental tests on lime mortars and bricks reinforced with hemp
Hemp is an agricultural product used for various applications. In the Civil Engineering field, only a limited use of this natural material, called the “green pig” since exploitation of all its constituent parts is allowed, has been done. For this reason, in the paper an experimental activity on lime mortars and bricks reinforced with hemp components has been performed. Compression and bending tests have been carried out on specimens manufactured with hemp shives and fibres, respectively. The achieved results have shown that hemp products change the failure modes from brittle to ductile, leaving basically unaltered the strength capacity of reinforced specimens with respect to unreinforced ones
A graphical approach to relational reasoning
Relational reasoning is concerned with relations over an unspecified domain of discourse. Two limitations to which it is customarily subject are: only dyadic relations are taken into account; all formulas are equations, having the same expressive power as first-order sentences in three variables. The relational formalism inherits from the Peirce-Schröder tradition, through contributions of Tarski and many others.
Algebraic manipulation of relational expressions (equations in particular) is much less natural than developing inferences in first-order logic; it may in fact appear to be overly machine-oriented for direct hand-based exploitation.
The situation radically changes when one resorts to a convenient representation of relations based on labeled graphs. The paper provides details of this representation, which abstracts w.r.t. inessential features of expressions.
Formal techniques illustrating three uses of the graph representation of relations are discussed: one technique deals with translating first-order specifications into the calculus of relations; another one, with inferring equalities within this calculus with the aid of convenient diagram-rewriting rules; a third one with checking, in the specialized framework of set theory, the definability of particular set operations. Examples of use of these techniques are produced; moreover, a promising approach to mechanization of graphical relational reasoning is outlined
Independent component analysis of interictal fMRI in focal epilepsy: comparison with general linear model-based EEG-correlated fMRI
The general linear model (GLM) has been used to analyze simultaneous EEG–fMRI to reveal BOLD changes linked to interictal epileptic discharges (IED) identified on scalp EEG. This approach is ineffective when IED are not evident in the EEG. Data-driven fMRI analysis techniques that do not require an EEG derived model may offer a solution in these circumstances. We compared the findings of independent components analysis (ICA) and EEG-based GLM analyses of fMRI data from eight patients with focal epilepsy. Spatial ICA was used to extract independent components (IC) which were automatically classified as either BOLD-related, motion artefacts, EPI-susceptibility artefacts, large blood vessels, noise at high spatial or temporal frequency. The classifier reduced the number of candidate IC by 78%, with an average of 16 BOLD-related IC. Concordance between the ICA and GLM-derived results was assessed based on spatio-temporal criteria. In each patient, one of the IC satisfied the criteria to correspond to IED-based GLM result. The remaining IC were consistent with BOLD patterns of spontaneous brain activity and may include epileptic activity that was not evident on the scalp EEG. In conclusion, ICA of fMRI is capable of revealing areas of epileptic activity in patients with focal epilepsy and may be useful for the analysis of EEG–fMRI data in which abnormalities are not apparent on scalp EEG
Laboratory tests on hydraulic lime mortar reinforced with jute fibres
Background: Considering the high seismic vulnerability of masonry buildings located in the Italian territory, the implementation of seismic retrofit programs is strongly needed.. With consideration for sustainable interventions, it is evident that the retrofit techniques to protect the historical heritage should be carried out with innovative green compound materials, such as mortars reinforced with natural fibres. Objective: In the current paper, laboratory tests on lime mortars strengthened with raw jute fibres have been performed. Methods: The workability of the fibre-reinforced mixture has been assessed through shaking table tests, and the mechanical resistances of standard specimens have been evaluated by bending and compression tests. Results: Considering the hygroscopic nature of jute, it has been identified that the optimal water/lime ratio and the maximum water percentage are absorbed by jute fibres. From the results, how the spreading of the mixture, which is indicative of the mortar consistency, changes with the water/lime ratio, has been evaluated. From bending tests, the effective behaviour of fibres, which provide a stitching effect of the failure crack in the investigated fibre-reinforced lime mortars, has been observed. Conclusion: Finally, the results of compression tests have shown that the examined fibre-reinforced mortars can be effectively used as building products according to the actual Italian technical code NTC 2018
Developmental refinement of cortical systems for speech and voice processing
Development typically leads to optimized and adaptive neural mechanisms for the processing of voice and speech. In this fMRI study we investigated how this adaptive processing reaches its mature efficiency by examining the effects of task, age and phonological skills on cortical responses to voice and speech in children (8-9years), adolescents (14-15years) and adults. Participants listened to vowels (/a/, /i/, /u/) spoken by different speakers (boy, girl, man) and performed delayed-match-to-sample tasks on vowel and speaker identity. Across age groups, similar behavioral accuracy and comparable sound evoked auditory cortical fMRI responses were observed. Analysis of task-related modulations indicated a developmental enhancement of responses in the (right) superior temporal cortex during the processing of speaker information. This effect was most evident through an analysis based on individually determined voice sensitive regions. Analysis of age effects indicated that the recruitment of regions in the temporal-parietal cortex and posterior cingulate/cingulate gyrus decreased with development. Beyond age-related changes, the strength of speech-evoked activity in left posterior and right middle superior temporal regions significantly scaled with individual differences in phonological skills. Together, these findings suggest a prolonged development of the cortical functional network for speech and voice processing. This development includes a progressive refinement of the neural mechanisms for the selection and analysis of auditory information relevant to the ongoing behavioral task
Interleaved lexical and audiovisual information can retune phoneme boundaries
To adapt to situations in which speech perception is difficult, listeners can adjust boundaries between phoneme categories using perceptual learning. Such adjustments can draw on lexical information in surrounding speech, or on visual cues via speech-reading. In the present study, listeners proved they were able to flexibly adjust the boundary between two plosive/stop consonants, /p/-/t/, using both lexical and speech-reading information and given the same experimental design for both cue types. Videos of a speaker pronouncing pseudo-words and audio recordings of Dutch words were presented in alternating blocks of either stimulus type. Listeners were able to switch between cues to adjust phoneme boundaries, and resulting effects were comparable to results from listeners receiving only a single source of information. Overall, audiovisual cues (i.e., the videos) produced the stronger effects, commensurate with their applicability for adapting to noisy environments. Lexical cues were able to induce effects with fewer exposure stimuli and a changing phoneme bias, in a design unlike most prior studies of lexical retuning. While lexical retuning effects were relatively weaker compared to audiovisual recalibration, this discrepancy could reflect how lexical retuning may be more suitable for adapting to speakers than to environments. Nonetheless, the presence of the lexical retuning effects suggests that it may be invoked at a faster rate than previously seen. In general, this technique has further illuminated the robustness of adaptability in speech perception, and offers the potential to enable further comparisons across differing forms of perceptual learning
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