Small cities for a small country: Sustaining the cultural renaissance?

Copyright @ 2006 RoutledgeThis chapter explores the implications for smaller cities of adopting culture-led regeneration strategies. It is suggested that there is a divergence between cultural planning for long term sustainable urban cultural renaissance and culture-led makeovers which rely on externally orientated projects devised to draw in new visitors, residents and enterprises. Drawing on evidence from Sheffield, an industrial city in South Yorkshire, northern England, it is suggested that small cities by thinking big, have been seduced into entering a culture-led city competition in which the stakes are high and the prospects of success limited

Rich mix cities: From multicultural experience to cosmopolitan engagement

Copyright @ 2004 Museum Tusculanum Press and ScanOC

From design to research: Upper limb prosthetic research and development in Canada, 1960-2000

This paper examines the history of the research and development (R&D) of myoelectric upper limb prosthesis in Canada from 1960 to 2000. It focuses on two of the prosthetic research and training units (PRTUs) that were created and funded by the federal government as a result of the Thalidomide tragedy: the Rehabilitation Centre at the Ontario Crippled Children’s Centre (OCCC) and successor organizations, and the University of New Brunswick’s (UNB) Institute of Biomedical Engineering (the Institute or IBME). Both developed commercial systems for myoelectrically controlled arms and hands. We argue that, in contrast to the common view that research in universities and public research institutions has increasingly moved away from basic problems and to product development and commercialization over the period, research in this field has moved in the opposite direction. We explore these cases in detail and examine the forces at work in this change from a design-oriented approach to one that became research intensive

Trace amine receptor in GtoPdb v.2023.1

Trace amine-associated receptors were discovered from a search for novel 5-HT receptors [9], where 15 mammalian orthologues were identified and divided into two families. The TA1 receptor (nomenclature as agreed by the NC-IUPHAR Subcommittee for the Trace amine receptor [58]) has affinity for the endogenous trace amines tyramine, β-phenylethylamine and octopamine in addition to the classical amine dopamine [9]. Emerging evidence suggests that TA1 is a modulator of monoaminergic activity in the brain [94] with TA1 and dopamine D2 receptors shown to form constitutive heterodimers when co-expressed [30]. In addition to trace amines, receptors can be activated by amphetamine-like psychostimulants, and endogenous thyronamines