130 research outputs found

    China's One-Child Policy and the Empowerment of Urban Daughters

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65532/1/aa.2002.104.4.1098.pd

    Content Maps of Health Care Problems in the Pre-clerkship Curriculum: Monitoring Themes, Gaps, Redundancies and Accreditation Requirements

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    The poster describes the content mapping process that aligned the learning priorities in the problem-based-learning pre-clerkship medical curriculum to accreditation standards and JABSOM’s graduation objectives. The resulting map serves as a resource for course directors to monitor content themes, determine curriculum gaps and redundancies, and address accreditation requirements

    Exploring the Impact of Tariffs on Foreign Direct Investment and Economic Prosperity

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    The global economic environment has become more interconnected, a significant portion of which can be attributed to countries welcoming foreign businesses through foreign direct investments (FDI). FDI is powerful in its ability to grow and develop home companies while shaping host economies, which lays out a critical role in the generating opportunities, strengthening economies, and the circulation or velocity of capital. This paper extends the initial work of Ranish, Mentz and Mohs (2015) relating to global value chain decision making. The purpose of this research is to review and outline the sensitivity to Tariff’s on FDI and economic growth. The conclusions, recommendations and implications reached in this study are generalizable and appropriate for developing best practice solutions

    Cahn--Hilliard inpainting with the double obstacle potential

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    The inpainting of damaged images has a wide range of applications, and many different mathematical methods have been proposed to solve this problem. Inpainting with the help of Cahn{Hilliard models has been particularly successful, and it turns out that Cahn{Hilliard inpainting with the double obstacle potential can lead to better results compared to inpainting with a smooth double well potential. However, a mathematical analysis of this approach is missing so far. In this paper we give first analytical results for a Cahn--Hilliard double obstacle inpainting model regarding existence of global solutions to the time-dependent problem and stationary solutions to the time-independent problem without constraints on the parameters involved. With the help of numerical results we show the effectiveness of the approach for binary and grayscale images

    Comunicar um destino: o film tourism como forma estratégica de promoção turística, o caso de Lisboa

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    Dissertação de Mestrado em Comunicação SocialO film tourism é uma das tendências para a realização de promoção de destinos turísticos. Este conceito permite ligar a área da comunicação nos media e o turismo de uma forma estratégica. Este é um fenómeno recente e ocorre devido à expansão a nível mundial do crescimento da indústria do entretenimento, mas também, devido ao aumento da possibilidade de se viajar e do tempo de lazer. O objetivo deste trabalho é compreender como é realizada a promoção turística através de produtos cinematográficos. Serão explorados dois exemplos de sucesso como a Escócia e a Nova Zelândia, destinos turísticos que tiraram partido do film tourism para se promover estrategicamente e se afirmarem no sector do turismo em relação a outros destinos. Para responder aos objetivos traçados foi realizado um estudo qualitativo para compreender como a cidade de Lisboa foi promovida através do filme “Comboio noturno para Lisboa”. Concluindo que, o filme contribuiu como fonte de promoção turística e para o desenvolvimento do sector do turismo, em Lisboa.Film tourism is one of the trends for promoting tourism destinations. This concept links the area of communication in the media and tourism in a strategic way. This is a recent phenomenon and is due to the worldwide expansion of the growth of the entertainment industry, but also due to the increased possibility of traveling and leisure time. The goal of this work is to understand how tourism promotion is carried out through cinematographic products. Two successful examples will be explored, such as Scotland and New Zealand, tourist destinations that have taken advantage of film tourism to promote themselves strategically and establish themselves in the tourism sector in relation to other destinations. In order to respond to the purposes outlined, a qualitative study was carried out to understand how the city of Lisbon was promoted through the analysis of the film "Night Train to Lisbon". We conclude that the film contributed as a source of tourism promotion and for the development of the tourism sector in Lisbon.N/

    A Cahn-Hilliard-Darcy model for tumour growth with chemotaxis and active transport

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    Using basic thermodynamical principles we derive a Cahn--Hilliard--Darcy model for tumour growth including nutrient diffusion, chemotaxis, active transport, adhesion, apoptosis and proliferation. The model generalise earlier models and in particular include active transport mechanisms which ensures thermodynamical consistency. We perform a formally matched asymptotic expansion and develop several sharp interface models. Some of them are classical and some new ones which for example include a jump in the nutrient density at the interface. A linear stability analysis for a growing nucleus is performed and in particular the role of the new active transport term is analysed. Numerical computations are performed to study the influence of the active transport term for specific growth scenarios

    Assessing the Need and Receptivity for an Integrated Healthy Sexual and Dating Relationships Intervention for Community College Students

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    Background: In emerging adulthood, youth often become involved in more serious romantic relationships. However, many lack the skills to avoid an unplanned pregnancy or sexually transmitted infection (STI), and to ensure a healthy dating relationship. Community college students serve nearly half of all undergraduate students in the United States; yet, community colleges typically lack resources for sexual health promotion. Purpose: To assess the need and receptivity for a web-based integrated healthy sexual and dating relationships intervention among community college students. Methods: In summer 2016, we partnered with three community colleges in South Central Texas to conduct an online survey of students’ sexual behaviors and dating relationships, and usability testing of activities from an integrated, web-based healthy sexual and dating relationship intervention. Results: Online survey participants (n=271) were 70% female, 38% Hispanic, 24% White, 17% Black, and 16% Asian; 20% self-identified as sexual minority; mean age was 20.8 years (SD = 2.05). Participants reported high rates of sexual risk behavior including sex without a condom or an effective birth control method, low use of long-acting reversible contraception, frequent use of emergency contraception, and low use of dual protection to prevent pregnancy and sexually transmitted infections. Two-thirds reported experiencing any type of dating violence perpetration or victimization in the past year. Usability testing participants (n=14) were 86% female, 42% Hispanic, 50% Asian/Pacific Islander, 14% Black, and 7% White; 71% were sexually experienced; mean age was 20.7 years (SD = 1.64). The web-based activities were highly rated in terms of usability parameters, and positively impacted short-term psychosocial outcomes related to condom use, accessing contraceptive health services, and constructive interpersonal conflict resolution. Conclusion: Findings underscore the high need and receptivity for an integrated healthy sexual and dating relationship web-based intervention among community college students, an understudied subgroup of youth in emerging adulthood

    PGE1 stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases

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    There is a growing appreciation that the cyclic adenosine monophosphate (cAMP)–protein kinase A (PKA) signaling pathway is organized to form transduction units that function to deliver specific messages. Such organization results in the local activation of PKA subsets through the generation of confined intracellular gradients of cAMP, but the mechanisms responsible for limiting the diffusion of cAMP largely remain to be clarified. In this study, by performing real-time imaging of cAMP, we show that prostaglandin 1 stimulation generates multiple contiguous, intracellular domains with different cAMP concentration in human embryonic kidney 293 cells. By using pharmacological and genetic manipulation of phosphodiesterases (PDEs), we demonstrate that compartmentalized PDE4B and PDE4D are responsible for selectively modulating the concentration of cAMP in individual subcellular compartments. We propose a model whereby compartmentalized PDEs, rather than representing an enzymatic barrier to cAMP diffusion, act as a sink to drain the second messenger from discrete locations, resulting in multiple and simultaneous domains with different cAMP concentrations irrespective of their distance from the site of cAMP synthesis

    A Radio Flare in the Long-Lived Afterglow of the Distant Short GRB 210726A: Energy Injection or a Reverse Shock from Shell Collisions?

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    We present the discovery of the radio afterglow of the short γ\gamma-ray burst (GRB) 210726A, localized to a galaxy at a photometric redshift of z2.4z\sim 2.4. While radio observations commenced 1 \lesssim 1~day after the burst, no radio emission was detected until 11\sim11~days. The radio afterglow subsequently brightened by a factor of 3\sim 3 in the span of a week, followed by a rapid decay (a ``radio flare''). We find that a forward shock afterglow model cannot self-consistently describe the multi-wavelength X-ray and radio data, and underpredicts the flux of the radio flare by a factor of 5\approx 5. We find that the addition of substantial energy injection, which increases the isotropic kinetic energy of the burst by a factor of 4\approx 4, or a reverse shock from a shell collision are viable solutions to match the broad-band behavior. At z2.4z\sim 2.4, GRB\,210726A is among the highest redshift short GRBs discovered to date as well as the most luminous in radio and X-rays. Combining and comparing all previous radio afterglow observations of short GRBs, we find that the majority of published radio searches conclude by 10 \lesssim 10~days after the burst, potentially missing these late rising, luminous radio afterglows.Comment: 28 pages, 10 figures, submitted to Ap
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