47 research outputs found
19. Place du ganglion sentinelle dans les carcinomes canalaires in situ étendus traités par mastectomie. Résultats de Protocole CINNAMOME
Hyperplasie canalaire atypique, critères liés à la sous-estimation après diagnostic par macrobiopsie stéréotaxique assistée par le vide (à partir d une série de 60 cas)
ANGERS-BU MĂ©decine-Pharmacie (490072105) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF
Mastectomie avec reconstruction mammaire après chimiothérapie et /ou radiothérapie préopératoire
REIMS-BU Santé (514542104) / SudocSudocFranceF
Clinical experience with 99mTc-MIBI scintimammography in patients with breast microcalcifications
Gastric metastatic extension of invasive ductal carcinoma of the breast with atypical endoscopic presentation
Enhancement of 3D modeling and classification of microcalcifications in breast computed tomography (BCT)
Nationwide molecular epidemiology of methicillin-resistant Staphylococcus aureus responsible for horse infections in France
Abstract Background The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) isolated in horse infections is not well documented, especially in France. The aim of the study was to evaluate the prevalence of MRSA isolates in horse infections from 2007 to 2013 in France and to characterize phenotypically and genotypically this collection. Results Out of 1393 S. aureus horse isolates, 85 (6.1%) were confirmed to be MRSA. Interestingly, the prevalence of MRSA significantly increased from 2007–2009 to 2010–2013 (0.7 vs. 9.5%, P <0.0001). Resistance to methicillin was due to the presence of the mecA gene in 84 strains (98.8%) while one strain (1.2%) possessed the mecC gene. The vast majority of the strains (83/85, 97.6%) was resistant to at least three different classes of antibiotics. Multi-locus sequence typing (MLST) showed that MRSA strains belonged mainly since not all belong to two sequence types (STs): ST398 (53/85, 62.4%) and ST8 (28/85, 32.9%). It is worth to note that all ST398 MRSA isolates were detected in the period 2010–2013. Other molecular typing methods were also used, such SCC mec analysis, spa typing and rep-PCR (Diversilab, bioMérieux). All these four techniques were in good agreement, with spa typing and rep-PCR being more discriminative than MLST and SCC mec typing. Conclusions This study is the first epidemiological study in France with extensive characterization of MRSA isolates associated with horse infections in stud farms. It shows that there is a significant increase of MRSA prevalence between 2007 and 2013, which mainly results from the spread of ST398 clones. It also highlights the importance of horses as a potential reservoir of important antimicrobial resistance genes