Internationalising small and medium sized enterprises (SMEs) a learning approach

This thesis investigates the learning processes of internationalising small and medium sized enterprises (SMEs). Based on a framework of absorptive capacity the research explores and examines: i. types and sources of new knowledge acquired by firms, ii. assimilation of new knowledge within firms, iii. exploitation of new capabilities gained and iv. outcomes of the new knowledge and learning. This research adopts a qualitative approach based on 12 longitudinal case studies of internationalising firms which were participating in the Scottish Enterprise Global Companies Development Programme. Multiple semi-structured interviews with the chief executive officers were carried out over a three year period and access was gained to Scottish Enterprise records and consultancy reports on the firms. This research provides new insights into the nature of knowledge used by internationalising firms and has clarified distinctions between different types of knowledge. Findings suggest that three types of knowledge – market, internationalisation and product/technological – were acquired depending on decisions facing firms at the time. Internationalisation knowledge was the most frequent new knowledge needed. This was knowledge which is specific to the internationalisation process or generic, which is applicable to overseas and domestic operations. Specific internationalisation knowledge is often developed by combining market and product knowledge. New insights are given into how firms acquire new knowledge from external, internal, experiential and objective sources of knowledge. To increase adsorptive capacity it was important for firms to create internal procedures and systems to convert tacit and individual knowledge to explicit and shared knowledge. The impact of new knowledge and learning on firms’ capabilities, decision making, competitive advantage and performance, and the constraints faced by firms are explored

Formative Experiences for Mindfulness-Based Stress Reduction Teachers-In-Training

Teacher development is of critical importance in the relatively new field of mindfulness. This study focuses on what can be understood about teacher development, from the perspective of teachers who have trained in this field. Five U.S.-based qualified Mindfulness-Based Stress Reduction teachers were interviewed to find out about their formative experiences. The data were gathered from interview transcriptions, and have been presented in the context of the literature concerning teacher training pathways and recognized and/or recommended teacher development activities. The teachers described a range of formative experiences, involving formal training, professional, spiritual and ordinary life moments, and including pleasant as well as unpleasant experiences. They related experience types that are encouraged for developing teachers, and some that extended beyond the recognized training pathways. The array of experiences they counted as formative can provide a powerful window into what teachers-intraining and teacher trainers might attend to, in encouraging aspiring and experienced teachers in their ongoing development

Mind Over Matter: A Qualitative Examination of the Coping Resources Used by Women with Cancer

Aim: This exploratory study investigates the coping resources used by six women diagnosed with cancer. Objective: The purpose of this study was to provide these women with the opportunity to discuss their cancer experiences along with the specific coping methods they found to be helpful throughout their journey. Methods: The participants, ranging in age from 25 to 63, completed a background questionnaire, followed by either a semi-structured interview (n=3) or an interview via written response (n=3). Results: Several key coping methods were described as being helpful to these women, and these methods fell into three major categories: intrapersonal, interpersonal, and extrapersonal coping resources. Although each of these resource categories had a direct influence on overall well-being itself, the interpersonal and extrapersonal resources also influenced the intrapersonal category, offering an alternate means by which they could influence overall well-being. These findings highlight the many coping resources used by these women when navigating their cancer journey

Reducing the Cost of Technical and Vocational Education

Teaching/Communication/Extension/Profession,

Sugar addiction: the state of the science.

PURPOSE: As obesity rates continue to climb, the notion that overconsumption reflects an underlying 'food addiction' (FA) has become increasingly influential. An increasingly popular theory is that sugar acts as an addictive agent, eliciting neurobiological changes similar to those seen in drug addiction. In this paper, we review the evidence in support of sugar addiction. METHODS: We reviewed the literature on food and sugar addiction and considered the evidence suggesting the addictiveness of highly processed foods, particularly those with high sugar content. We then examined the addictive potential of sugar by contrasting evidence from the animal and human neuroscience literature on drug and sugar addiction. RESULTS: We find little evidence to support sugar addiction in humans, and findings from the animal literature suggest that addiction-like behaviours, such as bingeing, occur only in the context of intermittent access to sugar. These behaviours likely arise from intermittent access to sweet tasting or highly palatable foods, not the neurochemical effects of sugar. CONCLUSION: Given the lack of evidence supporting it, we argue against a premature incorporation of sugar addiction into the scientific literature and public policy recommendations.Wellcome Trust (Senior Fellowship award)This is the final version of the article. It first appeared from Springer via http://dx.doi.org/10.1007/s00394-016-1229-

Online healthy lifestyle support in the perinatal period: What do women want and do they use it?

Unhealthy weight gain and retention during pregnancy and postpartum is detrimental to mother and child. Although various barriers limit the capacity for perinatal health care providers (PHCPs) to offer healthy lifestyle counselling, they could guide women to appropriate online resources. This paper presents a project designed to provide online information to promote healthy lifestyles in the perinatal period. Focus groups or interviews were held with 116 perinatal women and 76 PHCPs to determine what online information perinatal women and PHCPs want, in what form, and how best it should be presented. The results indicated that women wanted smartphone applications (apps) linked to trustworthy websites containing short answers to everyday concerns; information on local support services; and personalised tools to assess their nutrition, fitness and weight. Suggestions for improvement in these lifestyle areas should be practical and tailored to the developmental stage of their child. PHCPs wanted evidence-based, practical information, presented in a simple, engaging, interactive form. The outcome was a clinically endorsed website and app that health professionals could recommend. Preliminary evaluation showed that 10.5% of pregnant women in Western Australia signed up to the app. Use of the app appeared to be equitable across urban and rural areas of low to middle socioeconomic status

Proteolytic mechanisms involved in the metastasis of human melanoma cells

The metastatic process requires that tumour cells are capable of traversing various micro-environmental barriers, such as the basement membrane. There are various proteolytic mechanisms which could contribute to the process, plasminogen activation by tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA) is one such mechanism. Extensive reports in the literature (reviewed in the introduction) indicate that most tumour cells synthesize uPA and that it is this enzyme, particularly when receptor-bound, which plays a role in invasion. UCT-Mel 3 is a human malignant melanoma cell line which was established in our laboratory, and has been shown to be highly metastatic in the nude mouse. This cell line is typical of many melanomas in that it synthesizes only tPA and not uPA. In part 1 of this thesis I further investigated the plasminogen activator production by these cells (at the level of mRNA as well as activity) as well as expression of plasminogen activator inhibitor PAl-1 and receptors for tPA and uPA (uPAR). UCT-Mel 3 cells expressed uPAR although uPA was not detected. I also examined cells cultured from two metastatic deposits. Interestingly, the metastatic cells produced PAl-1 which was undetected in the parent cells. After confirming that UCT-Mel 3 do not express detectable levels of uPA, I attempted (in part 2) to determine whether tPA could play a comparable role to that of uPA in the invasive process. My strategy was to inhibit the expression of tPA via two different methods, namely the use of antisense RNA and ribozyme. I then hoped to isolate clones producing no tPA, which would have been injected into nude mice in order to assay for metastasis. Unfortunately, neither of these methods proved to be successful in abrogating tPA expression. I was thus unable to achieve the ultimate aim of the project. However, during the course of the study a number of unforeseen problems arose. Firstly, the clonal variation within the cell population, and secondly, my inability to obtain antisense transfectants. I have speculated that a possible reason for the latter may be that the cells are in fact unable to grow in the absence of tPA