21 research outputs found
Estudo longitudinal da população materno-infantil da região urbana do Sul do Brasil, 1993: aspectos metodológicos e resultados preliminares
Cell Kinetics Analysis in Patients Affected by Squamous Cell Carcinoma of the Head and Neck Treated with Primary Surgery and Adjuvant Radiotherapy
Clinically Useful Measures to Assess the Effectiveness of Treatments: Hints for a Proper Choice with Special Emphasis on Cancer Research
Performance indexes of a dot-enzime-linked immunosorbent assay (dot-ELISA) and an ezyme-linked immunosorbent assay (IgG-ELISA) for field surveys of new world leishmaniasis Índices de desempenho do dot-ELISA e do IgG-ELISA, em inquéritos soroepidemiológicos da leishmaniose do Novo Mundo
Diagnostic performance indexes of sensitivity, specificity, positive predictive value and efficiency were determined for dot-ELISA and IgG-ELISA tests in 340 leishmaniasis sera. Sensitivity of the dot-ELISA was significantly lower than IgG-ELISA's; the two tests had indexes of specificity and positive predictive value of the same magnitude. Seventy-eight sera gave a negative dot-ELISA test result and a positive IgG-ELISA test result. When sera were classified according to different criteria as how to interpret this diversity, the kappa statistic did not corroborate the classification indicating that the two tests display a substantial strength of agreement. The results presented indicate that performance indexes accrued in a survey where variables arc well known may be extrapolated to other population studies if the disease presents itself as highly prevalent (due to a selection bias or not) and may be expected to discriminate a disease status among test positives.<br>Índices de desempenho diagnóstico de sensibilidade, especificidade, valor preditivo positivo e eficiência foram determinados nas reações de dot-ELISA e IgG-ELISA em 340 soros de leishmaniose mucocutânea. A sensibilidade do dot-ELISA foi significativamente mais baixa que a da IgG-ELISA e os dois testes tiveram índices de especificidade e de valor de predição positivo da mesma magnitude. Setenta e oito soros tinham resultado negativo à reação de dot-ELISA e resultado positivo ao IgG-ELISA. Quando os soros foram examinados de acordo com diferentes critérios de análise, quanto a esta discrepância a estatística kappa não corroborou esta hipótese indicando que os dois testes concordavam substancialmente. Os resultados apresentados indicam que os índices de desempenho diagnóstico obtidos em trabalhos de campo onde haja boa caracterização das variáveis podem ser extrapolados a outros estudos populacionais desde que a doença se mostre de alta prevalência (devido a um viés de seleção ou não) e nestas condições se pode esperar que os índices façam o diagnóstico de doença entre os resultados positivos ao teste
Interobserver variation in the reporting of cervical colposcopic biopsy specimens: comparison of grading systems.
A new Magneto‐Inductive tracking technique to uncover subterranean activity: what do animals do underground?
Evaluation of the European Fish Index: false-positive and false-negative error rate to detect disturbance and consistency with alternative fish indices
Reliability and construct validity of the Dutch psychopathy checklist: youth version: findings from a sample of male adolescents in a juvenile justice treatment institution
The present study examines the reliability and construct validity of the Dutch version of the Psychopathy Check List: Youth Version (PCL:YV) in a sample of male adolescents admitted to a secure juvenile justice treatment institution (N = 98). Hare's four-factor model is used to examine reliability and validity of the separate dimensions of psychopathy. Interrater reliabilities are good to excellent for the PCL:YV total score and most factor scores, except for the affective factor. Several suggestions are offered for optimizing reliability of this factor. Finally, meaningful associations between PCL:YV scores and scores on the Minnesota Multiphasic Personality Inventory-Adolescent and the Interpersonal Checklist-Revised support the construct validity of the PCL:YV total score as well as the four factors in the Dutch contex