1,688 research outputs found

    I saw him first: Competitive nonverbal flirting among women, the tactics used and their perceived effectiveness

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    Here we explored nonverbal actions women use to flirt competitively against each other for the purposes of accessing a mate. We also investigated the perceived effectiveness of these competitive flirting actions. Using act nomination, Study 1 (n = 91) yielded 11 actions (eye contact with the man, dancing in his line of sight, smiling at him, touching him, giggling at his jokes, butting in between the other woman and the man, showing distaste for her, brushing against him, hugging him, flirting with other men, waving to him) for competitive flirtation against other women. Actions that signal possession (e.g., tie-signs) were predicted to be perceived as the most effective. While other actions were included in Study 2 (n = 139), results showed the most effective actions were tie-signs: touching him, initiating eye contact, hugging him, giggling at his jokes, and butting in between him and the rival. These findings are discussed in terms of prior research

    Mutant glycyl-tRNA synthetase (Gars) ameliorates SOD1G93A motor neuron degeneration phenotype but has little affect on Loa dynein heavy chain mutant mice

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    Background: In humans, mutations in the enzyme glycyl-tRNA synthetase (GARS) cause motor and sensory axon loss in the peripheral nervous system, and clinical phenotypes ranging from Charcot-Marie-Tooth neuropathy to a severe infantile form of spinal muscular atrophy. GARS is ubiquitously expressed and may have functions in addition to its canonical role in protein synthesis through catalyzing the addition of glycine to cognate tRNAs. Methodology/Principal findings: We have recently described a new mouse model with a point mutation in the Gars gene resulting in a cysteine to arginine change at residue 201. Heterozygous Gars^{C201R/+} mice have locomotor and sensory deficits. In an investigation of genetic mutations that lead to death of motor and sensory neurons, we have crossed the Gars^{C201R/+} mice to two other mutants: the TgSOD1^{G93A} model of human amyotrophic lateral sclerosis and the Legs at odd angles mouse (Dync1h1^{Loa}) which has a defect in the heavy chain of the dynein complex. We found the Dync1h1^{Loa/+}; Gars^{C201R/+} double heterozygous mice are more impaired than either parent, and this is may be an additive effect of both mutations. Surprisingly, the Gars^{C201R} mutation significantly delayed disease onset in the SOD1^{G93A}; Gars^{C201R/+} double heterozygous mutant mice and increased lifespan by 29% on the genetic background investigated. Conclusions/Significance: These findings raise intriguing possibilities for the study of pathogenetic mechanisms in all three mouse mutant strains

    Exploring how family carers of a person with dementia manage pre-death grief: A mixed methods study

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    Objectives: Many family carers of a person with dementia experience pre-death grief. We aimed to identify strategies that help carers manage pre-death grief. We hypothesised that emotion and problem focussed styles would be associated with lower, and dysfunctional coping with higher grief intensity. Methods: Mixed methods observational study using structured and semi-structured interviews with 150 family carers of people with dementia living at home or in a care home. Most participants were female (77%), caring for a parent (48%) or partner/spouse (47%) with mild (25%), moderate (43%) or severe (32%) dementia. They completed the Marwit-Meuser Caregiver Grief Inventory Short Form and the Brief Coping Orientation to Problems Experienced (Brief-COPE) questionnaire. We asked carers to identify strategies used for managing grief. We recorded field notes for 150 interviews and audio-recorded additional interviews with a sub-sample of 16 participants. Results: Correlations indicated that emotion-oriented coping was associated with lower grief (R = −0.341), and dysfunctional coping with higher grief (R = 0.435), with a small association with problem-focused strategies (R = −0.109), partly supporting our hypothesis. Our qualitative themes broadly match the three Brief-COPE styles. Unhelpful strategies of denial and avoidance align with dysfunctional coping strategies. Psychological strategies (including acceptance and humour) and seeking support were consistent with emotion-focused strategies, but we did not identify a theme relating to problem-focused strategies. Conclusion: Most carers identified multiple strategies for processing grief. Carers could readily identify supports and services that they found helpful for managing pre-death grief, yet current services appear under-resourced to meet growing demand. (ClinicalTrials.gov ID: NCT03332979)

    Thinking and acting both globally and locally : The Field School in intercultural education as a model for action-research training and civic learning.

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    We present the Field School model of intercultural civic education, service-learning, action research training, and collaboration (with local academic and community partners) based on field work in applied anthropology. Theoretical and methodological foundations of the Field School also include experiential learning and immersive pedagogy, multiculturalism and cross-cultural communication, international education and study abroad programs, collaborative international development, participatory research, and in-depth knowledge in one’s own specific discipline. The primary goals of these intensive, short-term action research projects in other, less-developed countries or regions are benefits for community partners that are as sustainable as possible and to foster and assess learning experiences of students. The Peabody-Vanderbilt Field School in Intercultural Education began in Ecuador and Argentina, but we focus on Field Schools in China, rural New Mexico, and South Africa. In Guangxi, P.R.C., U.S. and Chinese students learned to navigate political and cultural complexities to study migration, community needs and assets assessment, and health effects of changing diet on children, and assisted English language learning in schools, a university and a factory. Native American students from Gallup, NM, and students from Nashville, TN, travelled to each other’s locale to study the impact of diabetes in each culture and develop health education and other prevention strategies. In Cape Town, SA, students worked on health and education projects in three townships; we focus here on a collaboration with high school staff to study and reduce the high dropout rate. We analyze Field School impacts on local community partners and student-researchers

    Practical and emotional preparation for death: A mixed methods study investigating experiences of family carers of people with dementia

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    BACKGROUND: When family carers are more prepared for the end of the life of a person they care for, they report improved bereavement outcomes. Few studies have explored how carers prepare for the death of a person with dementia. We aimed to explore how carers for people with all stages of dementia experience preparing for end of life care and death. METHODS: This was a mixed methods cross-sectional study. Family carers of people with dementia (n = 150) completed a structured interview with validated scales, alongside questions about death preparedness and advance decisions. A sub-sample (n = 16) completed qualitative interviews exploring their experiences of planning for end of life. We fitted logistic regression models to explore associations with preparedness, and thematically analysed qualitative data. RESULTS: We addressed practical and emotional preparation separately for 143 participants. Fifty seven percent of participants were very practically prepared for death, while only 29% were very emotionally prepared. Male carers were more likely than female carers to report being very emotionally and practically prepared. Higher engagement with healthcare professionals was associated with feeling very practically prepared; although we found that formal discussions of end of life care issues with healthcare professionals did not impact carers’ feelings of preparation. Higher levels of dementia severity and carer depression were associated with feeling very emotionally prepared. Three qualitative themes related to practical and emotional preparation were identified: (1) ambiguity and uncertainty; (2) support from the system; and (3) how death is perceived by the carer. CONCLUSIONS: While most carers felt practically prepared for death, emotional preparation was much lower. Further research is needed to understand how engagement with healthcare professionals or other forms of social or emotional support could help carers, particularly female carers, to emotionally prepare for their relative’s death

    Practical and emotional preparation for death: A mixed methods study investigating experiences of family carers of people with dementia

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    BACKGROUND: When family carers are more prepared for the end of the life of a person they care for, they report improved bereavement outcomes. Few studies have explored how carers prepare for the death of a person with dementia. We aimed to explore how carers for people with all stages of dementia experience preparing for end of life care and death. METHODS: This was a mixed methods cross-sectional study. Family carers of people with dementia (n = 150) completed a structured interview with validated scales, alongside questions about death preparedness and advance decisions. A sub-sample (n = 16) completed qualitative interviews exploring their experiences of planning for end of life. We fitted logistic regression models to explore associations with preparedness, and thematically analysed qualitative data. RESULTS: We addressed practical and emotional preparation separately for 143 participants. Fifty seven percent of participants were very practically prepared for death, while only 29% were very emotionally prepared. Male carers were more likely than female carers to report being very emotionally and practically prepared. Higher engagement with healthcare professionals was associated with feeling very practically prepared; although we found that formal discussions of end of life care issues with healthcare professionals did not impact carers' feelings of preparation. Higher levels of dementia severity and carer depression were associated with feeling very emotionally prepared. Three qualitative themes related to practical and emotional preparation were identified: (1) ambiguity and uncertainty; (2) support from the system; and (3) how death is perceived by the carer. CONCLUSIONS: While most carers felt practically prepared for death, emotional preparation was much lower. Further research is needed to understand how engagement with healthcare professionals or other forms of social or emotional support could help carers, particularly female carers, to emotionally prepare for their relative's death

    Cancer Rehabilitation Publications (2008–2018) With a Focus on Physical Function: A Scoping Review

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    Background: Cancer rehabilitation research has accelerated over the last decade. However, closer examination of the published literature reveals that the majority of this work has focused on psychological interventions and cognitive and behavioral therapies. Recent initiatives have aggregated expert consensus around research priorities, highlighting a dearth in research regarding measurement of and interventions for physical function. Increasingly loud calls for the need to address the myriad of physical functional impairments that develop in people living with and beyond cancer have been published in the literature. A detailed survey of the landscape of published research has not been reported to our knowledge. Purpose: This scoping review systematically identified literature published between 2008 and 2018 related to the screening, assessment, and interventions associated with physical function in people living with and beyond cancer. Data Sources: PubMed and CINAHL were searched up to September 2018. Study Selection: Study selection included articles of all levels of evidence on any disease stage and population. A total of 11,483 articles were screened for eligibility, 2507 full-text articles were reviewed, and 1055 articles were selected for final inclusion and extraction. Data Extraction: Seven reviewers recorded type of cancer, disease stage, age of participants, phase of treatment, time since diagnosis, application to physical function, study design, impairments related to physical function, and measurement instruments used. Data Synthesis: Approximately one-third of the articles included patients with various cancer diagnoses (30.3%), whereas the rest focused on a single cancer, most commonly breast (24.8%). Most articles (77%) measured physical function following the completion of active cancer treatment with 64% representing the assessment domain. The most commonly used measures of physical function were the Medical Outcomes Study 36-Item Health Survey Questionnaire (29%) and the European Organization for Research and Treatment of cancer Quality of Life Questionnaire-Cancer 30 (21.5%). Limitations: Studies not written in English, study protocols, conference abstracts, and unpublished data were excluded. Conclusions: This review elucidated significant inconsistencies in the literature regarding language used to define physical function, measurement tools used to characterize function, and the use of those tools across the cancer treatment and survivorship trajectory. The findings suggested that physical function in cancer research is predominantly measured using general health-related quality-of-life tools rather than more precise functional assessment tools. Interdisciplinary and clinician-researcher collaborative efforts should be directed toward a unified definition and assessment of physical function

    Mitigation Ponds Offer Drought Resiliency for Western Spadefoot (Spea hammondii) Populations

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    Synergistic effects of habitat loss, drought, and climate change exacerbate amphibian declines. In southern California urbanization continues to convert natural habitat, while prolonged drought reduces surface water availability. Protection of biodiversity may be provided through mitigation; however, the long-term effectiveness of different strategies is often unreported. As a mitigation measure for building a new development within occupied Spea hammondii (western spadefoot) habitat in Orange County, California, artificial breeding pools were constructed at two off-site locations. Spea hammondii tadpoles were translocated from the pools at the development site to two off-site locations in 2005–2006. We conducted surveys a decade later (2016) to determine if S. hammondii were persisting and breeding successfully at either the original development site or the human-made pools at the two mitigation sites. We also verified hydroperiods of any existing pools at all three locations to see if any held water long enough for successful S. hammondii recruitment through metamorphosis. During our study, no pooling water was detected at two of three main sites surveyed, and no S. hammondii were observed at these locations. Twelve of the 14 pools created at only one of the two mitigation sites held water for over 30 d, and we detected successful breeding at seven of these pools. Recruitment in some mitigation ponds indicated that S. hammondii habitat can be created and maintained over 10+ yr, even during the fifth year of a catastrophic drought. Therefore, this may also serve as a conservation strategy to mitigate climate change and habitat loss. During our study, no pooling water was detected at two of three main sites surveyed, and no S. hammondii were observed at these locations. Twelve of the 14 pools created at a third site held water for over 30 days and we detected successful breeding at seven of these pools in 2016. Recruitment in some mitigation ponds indicated that S. hammondii habitat can be created and maintained over 10+ years, even during the fifth year of a catastrophic drought, therefore this may also serve as a management strategy for conservation with regard to climate change and habitat loss

    The Ursinus Weekly, February 12, 1962

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    Immortalized in fiction, poetry, Lorelei lends name to Ursinus • Two theologians visit U.C. campus this week; Seminary president, Convocation guest to speak • College President banquet speaker • Spring rushing periods begin • Auden to recite Tuesday at YMHA • Twelve frosh women to run for WSGA, WAA • PSEA to hear principal; U.C. to host conference • Troy Chapman returns; Discusses urban renewal • Editorial: For the love of Mike • Letters to the editor • Ursinus in the past • Cartoonist\u27s play: A review of Feiffer\u27s Crawling Arnold • Certain obscure ceremonials: The Locker-Lampson effect • Women hoopsters show no mercy • Ursinus grapplers grind two opponents; Elizabethtown, Lebanon Valley fall victim • Hoopsters bruise Blue Jays, 54 to 35 as nine game Bear losing skein ends • Bloodmobile here Monday afternoon • Dr. Armstrong seeking U.C. tourists for Europe • Graduate grants • Silver opinion contest conducted on campushttps://digitalcommons.ursinus.edu/weekly/1310/thumbnail.jp
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