3,815 research outputs found
Exploring student difficulties with observation location
Throughout introductory physics, students create and interpret free body
diagrams in which multiple forces act on an object, typically at a single
location (the object's center of mass). The situation increases in difficulty
when multiple objects are involved, and further when electric and magnetic
fields are present. In the latter, sources of the fields are often identified
as a set of electric charges or current-carrying wires, and students are asked
to determine the electric or magnetic field at a separate location defined as
the observation location. Previous research suggests students struggle with
accounting for how a measurement or calculation depends on the observation
location. We present preliminary results from a studio-style, algebra-based,
introductory electricity and magnetism course showing the prevalence of correct
and incorrect responses to questions about observation location by analyzing
student written work involving vector addition of fields
‘I really enjoy it’ : emotional engagement of university peer mentors
Peer mentoring programs are commonly used to facilitate the transition of new students into higher education settings. Peer mentors’ experiences and emotions during mentoring are important but under-researched. We report exploratory work to address this gap in a two-phase study using a grounded theory approach. In Phase 1 mentors in an Australian university responded to online (n=35) or face-to-face (n=10) questions about their emotions during a peer mentor program. Emotions were found to be primarily positive, mentors varied in the extent to which they express emotions, and emotions relating to different time points were evident. In Phase 2, we examined temporal dimensions of emotions in more depth with peer mentors in a German university and added anticipated future emotions to existing categories. Connections between mentors’ emotions and their own early experiences at university were explored, with another category of recalled prior emotions being added. Our findings are consistent with previous research regarding the positive and negative emotional aspects of being a peer mentor and further contribute to the understanding of the complexity of emotions in mentoring, specifically peer mentoring in higher education settings.peer-reviewe
Prostaglandins and cancer
ABSTRACT Prostaglandins (PGs) are lipids produced enzymatically and nonenzymatically from 20 carbon fatty acids, particularly arachidonic acid. Prostaglandins and related metabolites (collectively referred to as eicosanoids), including the thromboxanes, prostacyclins, hydroperoxy and hydroxy fatty acids, and leukotrienes are produced by most tissues of the body by oxidation of arachidonic acid, although the amount and class of product varies with cell type. The biological action of many of these eicosanoids as key regulators of cell processes that range from proliferation to adhesion and migration are currently being elucidated. An association of high levels of PGs and their synthetic enzymes, the PG synthases/cyclooxygenases, have been noted for many of the major types of cancer. Prostaglandins may contribute to the cancer processes through one or more of several mechanisms including increased proliferation, apoptosis, enhanced carcinogen metabolism or modulation of the immune system. The recent understanding of the regulation of substrate availability and of the regulation (or dysregulation in many _________________________________________________
The Status of Women Leaders in Utah Education
In September of 2013, the Center for American Progress released a report titled“ The State of Women in America: A 50- State Analysis of How Women Are Faring Across the Nation.” The report ranked Utah last of all 50 states in terms of women holding positions of decision making and leadership. Because the focus was solely on the percentage of women in elected office and private sector management positions, we determined that a more detailed look at the status of women and leadership in various sectors within the state would be useful. This is the third of four 2014 briefs, and it focuses on the status of women leaders in Utah education (higher and public K–12). The previous briefs highlighted data on women in Utah politics and nonprofit organizations, and the remaining one will focus on business. Each compares Utah data with national data and reviews applicable literature
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Mouse Genetic Models Reveal Surprising Functions of IκB Kinase Alpha in Skin Development and Skin Carcinogenesis
Gene knockout studies unexpectedly reveal a pivotal role for IκB kinase alpha (IKKα) in mouse embryonic skin development. Skin carcinogenesis experiments show that Ikkα heterozygous mice are highly susceptible to chemical carcinogen or ultraviolet B light (UVB) induced benign and malignant skin tumors in comparison to wild-type mice. IKKα deletion mediated by keratin 5 (K5).Cre or K15.Cre in keratinocytes induces epidermal hyperplasia and spontaneous skin squamous cell carcinomas (SCCs) in Ikkα floxed mice. On the other hand, transgenic mice overexpressing IKKα in the epidermis, under the control of a truncated loricrin promoter or K5 promoter, develop normal skin and show no defects in the formation of the epidermis and other epithelial organs, and the transgenic IKKα represses chemical carcinogen or UVB induced skin carcinogenesis. Moreover, IKKα deletion mediated by a mutation, which generates a stop codon in the Ikkα gene, has been reported in a human autosomal recessive lethal syndrome. Downregulated IKKα and Ikkα mutations and deletions are found in human skin SCCs. The collective evidence not only highlights the importance of IKKα in skin development, maintaining skin homeostasis, and preventing skin carcinogenesis, but also demonstrates that mouse models are extremely valuable tools for revealing the mechanisms underlying these biological events, leading our studies from bench side to bedside
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High calcium chemically defined culture medium
A high calcium chemically defined animal cell culture medium including vitamins A and D and a fatty acid or its ester. The medium is particularly adapted for the primary or secondary culture of epithelial cells. However, the medium may be utilized for establishing and maintaining cell lines, in particular myelomae and hybridomae.Board of Regents, University of Texas Syste
The Status of Women Leaders in Utah Nonprofits
In September 2013, the Center for American Progress released a report titled “ The State of Women in America: A 50- State Analysis of How Women Are Faring Across the Nation.” This report ranks Utah last of all 50 states in terms of women being in positions of decision making and leadership. Although the focus is solely on the percentage of women in elected office and private sector management positions, we feel that a more detailed look on the status of women in leadership in various sectors within the state would be useful. This is the second of four 2014 briefs, each of which compares national data with Utah data and provides a pertinent literature review. The first provides data on women in Utah politics; subsequent ones will focus on women leaders in education and business. This brief focuses on the status of women leaders in Utah nonprofit organizations
Prenatal exposure to methadone or buprenorphine: Early childhood developmental outcomes.
BACKGROUND: Methadone and buprenorphine are recommended to treat opioid use disorders during pregnancy. However, the literature on the relationship between longer-term effects of prenatal exposure to these medications and childhood development is both spare and inconsistent.
METHODS: Participants were 96 children and their mothers who participated in MOTHER, a randomized controlled trial of opioid-agonist pharmacotherapy during pregnancy. The present study examined child growth parameters, cognition, language abilities, sensory processing, and temperament from 0 to 36 months of the child\u27s life. Maternal perceptions of parenting stress, home environment, and addiction severity were also examined.
RESULTS: Tests of mean differences between children prenatally exposed to methadone vs. buprenorphine over the three-year period yielded 2/37 significant findings for children. Similarly, tests of mean differences between children treated for NAS relative to those not treated for NAS yielded 1/37 significant finding. Changes over time occurred for 27/37 child outcomes including expected child increases in weight, head and height, and overall gains in cognitive development, language abilities, sensory processing, and temperament. For mothers, significant changes over time in parenting stress (9/17 scales) suggested increasing difficulties with their children, notably seen in increasing parenting stress, but also an increasingly enriched home environment (4/7 scales).
CONCLUSIONS: Findings strongly suggest no deleterious effects of buprenorphine relative to methadone or of treatment for NAS severity relative to not-treated for NAS on growth, cognitive development, language abilities, sensory processing, and temperament. Moreover, findings suggest that prenatal opioid agonist exposure is not deleterious to normal physical and mental development
The Relationship Between Superintendent Servant Leadership Behavior and Principal Job Satisfaction in Iowa
Data from recent studies indicate that school principal turnover is high and that some principals suggest low job satisfaction levels. Superintendent leadership can influence the job satisfaction level of principals. This study examined the extent to which superintendent servant leadership behaviors correlate with principal job satisfaction. The population included all public school principals in the state. The final sample size consisted of 312 principals. The study utilized two survey instruments to explore superintendent servant leadership characteristics and job satisfaction data. The servant leadership characteristics included accountability, authenticity, courage, empowerment, forgiveness, humility, standing back, and stewardship. Questions investigating principal job satisfaction were broken into intrinsic and extrinsic subcategories. Results indicated a statistically significant relationship between superintendent servant leadership behavior and overall principal job satisfaction. Data also showed statistically significant relationships between each of the eight servant leadership characteristics and overall principal job satisfaction
Analyzing Commercial Video Game Instruction through the Lens of Instructional Design
This paper will examine how Gagne’s Nine Events of Instruction (1992) may appear, perhaps inadvertently, within commercial games that guide the user from novice to expert player. By employing a qualitative artifact analysis methodology, we examine a popular action adventure video game to determine if game designers encourage players to build game expertise by employing similar events to Gagne’s instructional design model. We demonstrate that our artifact of analysis does consistently employ Gagne’s events, though often in a manner unique to a digitally mediated space. We conclude that an experiential game setting has the potential to be a platform for instructional delivery
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