77 research outputs found
Ongoing monkeypox virus outbreak, Portugal, 29 April to 23 May 2022
Up to 27 May 2022, Portugal has detected 96 confirmed
cases of monkeypox. We describe 27 confirmed
cases (median age: 33 years (range: 22â51); all males),
with an earliest symptom onset date of 29 April.
Almost all cases (n = 25) live in the Lisbon and Tagus
Valley health region. Most cases were neither part of
identified transmission chains, nor linked to travel or
had contact with symptomatic persons or with animals,
suggesting the possible previously undetected
spread of monkeypox.info:eu-repo/semantics/publishedVersio
Local ecological knowledge of fishers about the life cycle and temporal patterns in the migration of mullet (Mugil liza) in Southern Brazil
A fuzzy decision support system for meta-evaluation a new approach and a case study performed in Brazil
Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
Follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL) are the two most common non-Hodgkin lymphomas (NHLs). Here we sequenced tumour and matched normal DNA from 13 DLBCL cases and one FL case to identify genes with mutations in B-cell NHL. We analysed RNA-seq data from these and another 113 NHLs to identify genes with candidate mutations, and then re-sequenced tumour and matched normal DNA from these cases to confirm 109 genes with multiple somatic mutations. Genes with roles in histone modification were frequent targets of somatic mutation. For example, 32% of DLBCL and 89% of FL cases had somatic mutations in MLL2, which encodes a histone methyltransferase, and 11.4% and 13.4% of DLBCL and FL cases, respectively, had mutations in MEF2B, a calcium-regulated gene that cooperates with CREBBP and EP300 in acetylating histones. Our analysis suggests a previously unappreciated disruption of chromatin biology in lymphomagenesis
O estado do Rio de Janeiro como limite sul e norte de distribuição de algumas espécies de aves
A ETNOECOLOGIA EM PERSPECTIVA: ORIGENS, INTERFACES E CORRENTES ATUAIS DE UM CAMPO EM ASCENSĂO
A Novel Method for Inducing Nerve Growth via Modulation of Host Resting Potential: Gap Junction-Mediated and Serotonergic Signaling Mechanisms
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