The Wolf and the Dog: eristic, elenchus, and kinds of wisdom in Plato’s Euthydemus

In Plato’s Sophist, the Stranger warns Theaetetus not to let the similarities between the sophist and the practitioner of the elenctic method blind him to their crucial differences, alluding to the resemblance of a wolf to a dog, «the most savage of animals to the most gentle» (231a6). All the same, Plato has the Eleatic Stranger describe the master of elenchus – the method for which Socrates was famous – as a sophist, albeit a sophist of noble birth (231b7-8), leading scholars to ask whether Plato in his later period regarded Socrates’ method as essentially sophistic, and to that extent dubious and destructive. In this paper I argue that by looking to the illustration of the elenctic and sophistic methods in the Euthydemus, we can see that in several significant respects, Plato regarded the similarities as merely apparent. In particular, I argue, the elenctic method is presented as a constructive method, which facilitates the interlocutor’s articulation and awareness of tacit beliefs about the subject under investigation. Some of these beliefs are tacit in the familiar sense that the interlocutor is already disposed to affirm their content. Other beliefs, however, are a special kind of tacit belief, in that although they follow immediately, or in a very small number of inferential steps from the interlocutor’s pre-existing, explicitly held beliefs, they are not beliefs the interlocutor is disposed to affirm at the outset of the enquiry. The elenctic method is, therefore, able to bring the interlocutor to self- knowledge concerning their own beliefs, and the relations of entailment between them, concerning the subject of inquiry

A 360 degree approach to resolving uncertainty and prioritising delivery of coastal adaptation, resilience and environmental protection for the future economic growth of Jersey, Channel Isles

The island of Jersey has a rich history influenced by natural and man-made change; particularly the fortifications constructed as defensive structures during periods of conflict, from the Napoleonic period through to 1940’s. Over the next century Jersey faces a growing challenge from the predicted impacts of climate change via rising sea levels combined with increasingly intense rainfall which will result in an increase to the extents of coastal and pluvial flooding. Jersey needs to be prepared and resilient; to support a digital Island that attracts international business, providing a secure and safe location. Jersey’s shoreline policies balance the Island’s environmental legislation and economic policies, but a priority for the Government is flood avoidance, mitigation and development opportunities through planning policy and asset adaptation in a way that supports the Island’s prosperity. This includes consideration of advancing the ‘defence’ line. A 360 degree approach is taken to deliver an island wide coastal resilience plan, which includes pluvial flooding as well as coastal flooding – the outcome will be the Jersey Shoreline Management Plan (SMP). This paper presents the first ever emerging coastal flood and erosion mapping for the whole island under the jurisdiction of the Government of Jersey. The mapping is supported by shoreline planning and policy over the next 20, 50 and 100 years, which augments the plan for integrated coastal management based on the Government’s environmental, community and economic objectives for the island

Does a lack of social support and perceived stigma influence the relationship between motor neurone disease-related stress and psychological distress?

Objectives This study aimed to investigate the mechanisms through which social support and felt stigma influence the relationship between motor neurone disease (MND)‐related stress and psychological distress for people with MND. Although a lack of social support has been identified as a significant predictor of psychological distress for individuals with MND, the mechanisms through which this relationship exists have not been assessed, nor have the predictive nature of stigma. Furthermore, the theoretical model specifying the effects of enacted stigma on self‐stigma has not been tested in individuals with MND. Design A cross‐sectional design utilizing an online survey method was used. It was hypothesized that social support would moderate the relationship between MND‐related stress (operationalized as enacted stigma or physical functioning) and psychological distress (operationalized as depression, anxiety, and stress). Furthermore, felt stigma would significantly mediate the relationship between MND‐related stress (enacted stigma) and psychological distress. Methods Individuals with a diagnosis of MND were recruited internationally through social media and through various organizations and support services. Seventy‐seven participants completed the online survey. Results Significant correlations were identified between social support, felt, and enacted stigma and psychological distress. Moderation analysis was not significant. However, the mediation analyses identified felt stigma as a significant mediator of the relationship between enacted stigma and psychological distress. A direct relationship between enacted stigma and stress (but not depression and anxiety) was also evident. Conclusions A comprehensive approach to tackling stigma is important in ameliorating psychological distress for people with MND. Limitations of the current study are discussed, along with implications for clinical practice

Online therapy with families ‐ what can families tell us about how to do this well? A qualitative study assessing families’ experience of remote Dyadic Developmental Psychotherapy compared to face-to-face therapy

Dyadic Developmental Psychotherapy (DDP) is a family-based therapy for adopted children aiming to achieve secure attachment between the child and parent. Due to restrictions under the COVID-19 pandemic, delivery of DDP transitioned from face-to-face to online methods. This study aimed to explore families experience of online DDP compared to face-to-face DDP, looking at the advantages and disadvantages of remote delivery methods and the implications this has on future service delivery for clinicians. Semi-structured interviews with 6 families were conducted online. Analysis of transcripts using Interpretative Phenomenological Analysis (IPA) revealed four superordinate themes: environment and child engagement, non-verbal communication, travel and familiarity with remote interactions. Parents recognised the influence the physical and online environment had on their child’s engagement levels, however, varied in their experience and hence preference of delivery method. All families emphasised the importance of non-verbal communication within DDP sessions and majority highlighted this may be lost online. For families who travelled to face-to-face DDP, car journeys provided a unique opportunity to decompress and reflect after sessions. For families where travel is unfeasible, online DDP was a lifeline, demonstrating the ability of remote therapy to widen access to specialist healthcare. Familiarity with online work emerged as a strong indicator of positive attitudes towards remote DDP, especially if the previous experience is positive and the child is confident using technology. Overall, families differed greatly in their experience of remote and face-to-face DDP indicating a new approach must be undertaken with each family beginning therapy, ensuring it is unique and individual to their needs

Editorial: There's an AI for that

In recent months, the educators and higher education institutions have responded with concern, critique, and hope, to the rise of generative artificial intelligence (AI)’s unregulated and mounting influence. Following the period of emergency remote teaching, and the great ‘snapback’ (Jandrić et al., 2022), yet another new concern has emerged, promising to revolutionise education, or threaten its existence. The gravity of the situation has reverberated across the system, as wizardry of predictive pattern recognition fundamentally threatens the validity of long-held practices of summative assessments including essays, and online quizzes. This latest quandary/crisis shows no sign of abating, as venture capitalist funding and language modelling datasets grow. The technology becomes more deeply integrated into word processing, and cloud-based applications through which much of our academic labour is conducted. Understanding and conceptualising new technology within education has long been a necessity, as we wrestle with wrangling tools into our human interactions. Higher education’s relationship with edtech has always been characterised by a cyclical response to disruptive external influences of evolving technology, whose recent developments are often underpinned by neoliberal values of competition, efficiency, market-based solutions, and the privatisation of software platforms. Recent large language model developments are proving no different, with deregulation and the free market serving as the impetus to design and create such tools. Across higher education, educators scramble to decode the GenAI black box, deciphering hallucinations, confabulations, and smooth outputs indistinguishable from original student work. Policy responses range along a continuum of ban or embrace. New AI literacies are being woven into curricula, as change continues apace. 2023 marks a year of existential crisis precipitated by a global pandemic, followed by geopolitical events and a fatigue from the continual adaptation to a new normal. Even within, we are constantly shaping our educational systems. That pull is in many different directions – to accredit, to certify, to help learners become, to socialise, to emancipate, to measure - to meet very diverse purposes and aims. The politics and power structures inherent in our system further affect our response (Kuhn et al., 2023).  While the potential of AI chatbots based on natural language processing models is undeniable, it is crucial to discern the reality from the hype and to better understand how our actions and responses are shaping our educational systems in this evolving domain. This editorial examines this dilemma further, to consider the impact on our scholarship of teaching and learning and how we as a community of researchers and educators respond

Association mapping of partitioning loci in barley

BACKGROUND: Association mapping, initially developed in human disease genetics, is now being applied to plant species. The model species Arabidopsis provided some of the first examples of association mapping in plants, identifying previously cloned flowering time genes, despite high population sub-structure. More recently, association genetics has been applied to barley, where breeding activity has resulted in a high degree of population sub-structure. A major genotypic division within barley is that between winter- and spring-sown varieties, which differ in their requirement for vernalization to promote subsequent flowering. To date, all attempts to validate association genetics in barley by identifying major flowering time loci that control vernalization requirement (VRN-H1 and VRN-H2) have failed. Here, we validate the use of association genetics in barley by identifying VRN-H1 and VRN-H2, despite their prominent role in determining population sub-structure. RESULTS: By taking barley as a typical inbreeding crop, and seasonal growth habit as a major partitioning phenotype, we develop an association mapping approach which successfully identifies VRN-H1 and VRN-H2, the underlying loci largely responsible for this agronomic division. We find a combination of Structured Association followed by Genomic Control to correct for population structure and inflation of the test statistic, resolved significant associations only with VRN-H1 and the VRN-H2 candidate genes, as well as two genes closely linked to VRN-H1 (HvCSFs1 and HvPHYC). CONCLUSION: We show that, after employing appropriate statistical methods to correct for population sub-structure, the genome-wide partitioning effect of allelic status at VRN-H1 and VRN-H2 does not result in the high levels of spurious association expected to occur in highly structured samples. Furthermore, we demonstrate that both VRN-H1 and the candidate VRN-H2 genes can be identified using association mapping. Discrimination between intragenic VRN-H1 markers was achieved, indicating that candidate causative polymorphisms may be discerned and prioritised within a larger set of positive associations. This proof of concept study demonstrates the feasibility of association mapping in barley, even within highly structured populations. A major advantage of this method is that it does not require large numbers of genome-wide markers, and is therefore suitable for fine mapping and candidate gene evaluation, especially in species for which large numbers of genetic markers are either unavailable or too costly

Interactions between Teladorsagia circumcincta infections and microbial composition of sheep with or without successful monepantel treatment:A preliminary study

Nematodes are one of the main impactors on the health, welfare and productivity of farmed animals. Teladorsagia circumcincta are endemic throughout many sheep-producing countries, particularly in the northern hemisphere, and contribute to the pathology and economic losses seen on many farms. Control of these nematode infections is essential and heavily reliant on chemotherapy (anthelmintics), but this has been compromised by the development of anthelmintic resistance. In mammals, the composition of the intestinal microbiota has been shown to have a significant effect on overall health. The interactions between host, microbiota and pathogens are complex and influenced by numerous factors. In this study, comparisons between intestinal and faecal microbiota of sheep infected with sensitive or resistant strains of T. circumcincta, with or without monepantel administration were assessed. The findings from both faecal samples and terminal ileum mucosal scrapings showed clear differences between successfully treated animals and those sheep that were left untreated and/or those carrying resistant nematodes. Specifically, the potentially beneficial genus Bifidobacterium was identified as elevated in successfully treated animals. The detection of these and other biomarkers will provide the basis for new therapeutic reagents particularly relevant to the problems of emerging multidrug anthelmintic resistance

A comparative study of the effects of four treatment regimes on ivermectin efficacy, body weight and pasture contamination in lambs naturally infected with gastrointestinal nematodes in Scotland

AbstractRefugia-based drenching regimes have been widely recommended to slow development of anthelmintic resistance but there are few comparisons between different treatment approaches in the UK. The impact of four ivermectin treatment regimes on drug efficacy, lamb body weight and nematode contamination during a 154 day grazing season were evaluated in a consecutive five year field study. Regimes were whole-flock treatment every 4weeks (NST), targeted selective treatment (TST) based on individual performance, strategic whole-flock treatments at pre-determined times (SPT) or whole-flock treatment when clinical signs were apparent (MT). Mean numbers of ivermectin drenches administered per season were 4.0, 1.8, 2.0 and 1.4 for NST, TST, SPT and MT groups, respectively. The mean anthelmintic efficacy (AE) for each treatment group was based on faecal egg count reduction post-treatment employing a bootstrap sampling based algorithm. Mean AE was 95–98% for all groups in 2006 and mean AE (95% confidence limits) for NST declined to 62% (55%, 68%) in 2010. In comparison, AE for TST, SPT and MT in 2010 were 86% (81%, 92%), 86% (83%, 90%) and 83% (78%, 88%), respectively. Body weight in TST and SPT was similar to NST in all years (p>0.05), however MT lambs were lighter than NST in 2006–2008 (p⩽0.04). Tracer lamb worm burdens was lowest in NST but was not significantly different between other groups. Overall, both the TST and SPT regimes appeared to maintain animal performance and conserve anthelmintic efficacy compared with a neo-suppressive anthelmintic treatment regime