6,254 research outputs found
Is the Make-Buy Decision Process a Core Competence?
Many of today's products are so complex that no single company has all the necessary knowledge about either the product or the required processes to completely design and manufacture them in-house. As a result, most companies are dependent on others for crucial elements of their corporate well-being. Typically, however, companies have some choice as to whom they become dependent upon and for what sorts of skills and competences. That is, although few companies can "do it all," most have significant
influence over the strategic choice of corporate identity and what businesses to be in. What is the range of choices they face? How are different companies making those choices? Can we make sense of the variety of decisions we can
observe now in different industries or different parts of the world? What are the skills that companies must retain?
In this paper we address the challenge of making these choices rationally. We give examples in which similar companies, facing similar choices, select make/buy patterns in very different ways, resulting in very different patterns
of interdependencies along companies' supply chains. These choices are not
restricted to skills related to the product, but include choices related to key
design and manufacturing issues. To make sense of these differences, we
propose a framework that ties together the following engineering and
management concepts into one coherent view:
1) core competencies
2) the product development process
3) systems engineering
4) product architecture and modularity, and
5) supply chain design.ONR and various MIT programs including Leaders for Manufacturing,
International Motor Vehicle Program, Industrial Performance Center, Japan Program, International Center for Management of Technology
Seasonal variation in sonic muscles in the fawn cusk-eel <i>Lepophidium profundorum</i>
The fawn cusk-eel Lepophidium profundorum (Ophidiidae) has an unusual sound-producing system with sexually dimorphic sets of antagonistic muscles. Outside the mating season, the dorsal and ventral muscles are well developed and larger in males than in females, but the tiny intermediate muscles are smaller, suggesting a minor role, if any, in male advertisement call production. We examined summer individuals with more developed gonads and find a fourfold hypertrophy of the intermediate but not the other muscles. This result suggests androgen dependence and an important role in sound production for the intermediate muscle. Even though both sexes gain weight in the summer, the ventral and dorsal muscles in females lose weight, suggesting that sound production is less important in females and that muscle mass may be used to support egg growth
On Zurek's derivation of the Born rule
Recently, W. H. Zurek presented a novel derivation of the Born rule based on
a mechanism termed environment-assisted invariance, or "envariance" [W. H.
Zurek, Phys. Rev. Lett. 90(2), 120404 (2003)]. We review this approach and
identify fundamental assumptions that have implicitly entered into it,
emphasizing issues that any such derivation is likely to face.Comment: 8 pages; v2: minor clarifications added; v3: reference to Zurek's
quant-ph/0405161 added. To appear in Foundations of Physics (Cushing Volume
Numerical Simulation of Vortex Crystals and Merging in N-Point Vortex Systems with Circular Boundary
In two-dimensional (2D) inviscid incompressible flow, low background
vorticity distribution accelerates intense vortices (clumps) to merge each
other and to array in the symmetric pattern which is called ``vortex
crystals''; they are observed in the experiments on pure electron plasma and
the simulations of Euler fluid. Vortex merger is thought to be a result of
negative ``temperature'' introduced by L. Onsager. Slight difference in the
initial distribution from this leads to ``vortex crystals''. We study these
phenomena by examining N-point vortex systems governed by the Hamilton
equations of motion. First, we study a three-point vortex system without
background distribution. It is known that a N-point vortex system with boundary
exhibits chaotic behavior for N\geq 3. In order to investigate the properties
of the phase space structure of this three-point vortex system with circular
boundary, we examine the Poincar\'e plot of this system. Then we show that
topology of the Poincar\'e plot of this system drastically changes when the
parameters, which are concerned with the sign of ``temperature'', are varied.
Next, we introduce a formula for energy spectrum of a N-point vortex system
with circular boundary. Further, carrying out numerical computation, we
reproduce a vortex crystal and a vortex merger in a few hundred point vortices
system. We confirm that the energy of vortices is transferred from the clumps
to the background in the course of vortex crystallization. In the vortex
merging process, we numerically calculate the energy spectrum introduced above
and confirm that it behaves as k^{-\alpha},(\alpha\approx 2.2-2.8) at the
region 10^0<k<10^1 after the merging.Comment: 30 pages, 11 figures. to be published in Journal of Physical Society
of Japan Vol.74 No.
Inherited epidermolysis bullosa
Inherited epidermolysis bullosa (EB) encompasses a number of disorders characterized by recurrent blister formation as the result of structural fragility within the skin and selected other tissues. All types and subtypes of EB are rare; the overall incidence and prevalence of the disease within the United States is approximately 19 per one million live births and 8 per one million population, respectively. Clinical manifestations range widely, from localized blistering of the hands and feet to generalized blistering of the skin and oral cavity, and injury to many internal organs. Each EB subtype is known to arise from mutations within the genes encoding for several different proteins, each of which is intimately involved in the maintenance of keratinocyte structural stability or adhesion of the keratinocyte to the underlying dermis. EB is best diagnosed and subclassified by the collective findings obtained via detailed personal and family history, in concert with the results of immunofluorescence antigenic mapping, transmission electron microscopy, and in some cases, by DNA analysis. Optimal patient management requires a multidisciplinary approach, and revolves around the protection of susceptible tissues against trauma, use of sophisticated wound care dressings, aggressive nutritional support, and early medical or surgical interventions to correct whenever possible the extracutaneous complications. Prognosis varies considerably and is based on both EB subtype and the overall health of the patient
Transverse Demagnetization Dynamics of a Unitary Fermi Gas
Understanding the quantum dynamics of strongly interacting fermions is a
problem relevant to diverse forms of matter, including high-temperature
superconductors, neutron stars, and quark-gluon plasma. An appealing benchmark
is offered by cold atomic gases in the unitary limit of strong interactions.
Here we study the dynamics of a transversely magnetized unitary Fermi gas in an
inhomogeneous magnetic field. We observe the demagnetization of the gas, caused
by diffusive spin transport. At low temperatures, the diffusion constant
saturates to the conjectured quantum-mechanical lower bound ,
where is the particle mass. The development of pair correlations,
indicating the transformation of the initially non-interacting gas towards a
unitary spin mixture, is observed by measuring Tan's contact parameter.Comment: 8 pages, 6 figures. Accepted versio
Agile Manufacturing and Customer- Supplier Relations in the Auto and Aircraft Industries
Presentation on agile manufacturing and customer-supplier relations in auto and aircraft industrie
Research in the Restricted Problems of Three and Four Bodies Final Scientific Report
Seven studies have been conducted on research in the existence and nature of solutions of the restricted problems of three and four bodies. The details and results of five of these research investigations have already been published, and the latest two studies will be published shortly. A complete bibliography of publications is included in this report. This research has been primarily qualitative and has yielded new information on the behavior of trajectories near the libration points in the Earth-Moon-Sun and Sun-Jupiter-Saturn systems, and on the existence of periodic trajectories about the libration points of the circular and elliptical restricted four-body models. We have also implemented Birkhoff's normalization process for conservative and nonconservative Hamiltonian systems with equilibrium points. This makes available a technique for analyzing stability properties of certain nonlinear dynamical systems, and we have applied this technique to the circular and elliptical restricted three-body models. A related study was also conducted to determine the feasibility of using cislunar periodic trajectories for various space missions. Preliminary results suggest that this concept is attractive for space flight safety operations in cislunar space. Results of this research will be of interest to mathematicians, particularly those working in ordinary differential equations, dynamical systems and celestial mechanics; to astronomers; and to space guidance and mission analysts
Probabilities from Entanglement, Born's Rule from Envariance
I show how probabilities arise in quantum physics by exploring implications
of {\it environment - assisted invariance} or {\it envariance}, a recently
discovered symmetry exhibited by entangled quantum systems. Envariance of
perfectly entangled ``Bell-like'' states can be used to rigorously justify
complete ignorance of the observer about the outcome of any measurement on
either of the members of the entangled pair. For more general states,
envariance leads to Born's rule, for the outcomes
associated with Schmidt states. Probabilities derived in this manner are an
objective reflection of the underlying state of the system -- they represent
experimentally verifiable symmetries, and not just a subjective ``state of
knowledge'' of the observer. Envariance - based approach is compared with and
found superior to pre-quantum definitions of probability including the {\it
standard definition} based on the `principle of indifference' due to Laplace,
and the {\it relative frequency approach} advocated by von Mises. Implications
of envariance for the interpretation of quantum theory go beyond the derivation
of Born's rule: Envariance is enough to establish dynamical independence of
preferred branches of the evolving state vector of the composite system, and,
thus, to arrive at the {\it environment - induced superselection (einselection)
of pointer states}, that was usually derived by an appeal to decoherence.
Envariant origin of Born's rule for probabilities sheds a new light on the
relation between ignorance (and hence, information) and the nature of quantum
states.Comment: Figure and an appendix (Born's rule for continuous spectra) added.
Presentation improved. (Comments still welcome...
Realism and the wave-function
Realism -- the idea that the concepts in physical theories refer to 'things'
existing in the real world -- is introduced as a tool to analyze the status of
the wave-function. Although the physical entities are recognized by the
existence of invariant quantities, examples from classical and quantum physics
suggest that not all the theoretical terms refer to the entities: some terms
refer to properties of the entities, and some terms have only an epistemic
function. In particular, it is argued that the wave-function may be written in
terms of classical non-referring and epistemic terms. The implications for
realist interpretations of quantum mechanics and on the teaching of quantum
physics are examined.Comment: No figure
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