Unilaterale sino-orbitale en subcutane aspergillose bij een kat

After a period of sneezing and conjunctivitis, a young female cat was presented with leftsided facial subcutaneous swellings and ocular disease characterized by a hyperemic conjunctiva with protrusion of the third eyelid. In the oral cavity, swellings were present labial of the premolar teeth and in the pterygopalatine fossa. The left submandibular lymphnode was enlarged. The cat sneezed from time to time but there was no nasal discharge. The skin lesions had a distinctive yellow color. Cytology of affected skin revealed pyogranulomatous inflammation with eosinophils. Only deep sampling of the skin contained representative tissue for cytologic, histopathologic and mycologic examination. Aspergillus section fumigatus was diagnosed on morphologic aspects of the mycologic culture and the fungus was identified by molecular technology as Aspergillus viridinutans. The definite diagnosis was sino-orbital aspergillosis with extensive subcutaneous invasion. Due to progressive disease despite therapy, the cat was euthanized