Inventory of current EU paediatric vision and hearing screening programmes

Background: We examined the diversity in paediatric vision and hearing screening programmes in Europe. Methods: Themes relevant for comparison of screening programmes were derived from literature and used to compile three questionnaires on vision, hearing and public-health screening. Tests used, professions involved, age and frequency of testing seem to influence sensitivity, specificity and costs most. Questionnaires were sent to ophthalmologists, orthoptists, otolaryngologists and audiologists involved in paediatric screening in all EU fullmember, candidate and associate states. Answers were cross-checked. Results: Thirty-nine countries participated; 35 have a vision screening programme, 33 a nation-wide neonatal hearing screening programme. Visual acuity (VA) is measured in 35 countries, in 71% more than once. First measurement of VA varies from three to seven years of age, but is usually before the age of five. At age three and four picture charts, including Lea Hyvarinen are used most, in children over four Tumbling-E and Snellen. As first hearing screening test otoacoustic emission (OAE) is used most in healthy neonates, and auditory brainstem response (ABR) in premature newborns. The majority of hearing testing programmes are staged; children are referred after one to four abnormal tests. Vision screening is performed mostly by paediatricians, ophthalmologists or nurses. Funding is mostly by health insurance or state. Coverage was reported as >95% in half of countries, but reporting was often not first-hand. Conclusion: Largest differences were found in VA charts used (12), professions involved in vision screening (10), number of hearing screening tests before referral (1-4) and funding sources (8)

Blogging While Female: How Internet Misogyny Parallels Real-World Harassment

In early March 2007, The Washington Post published a front-page article titled Harsh Words Die Hard on the Web: Law Students Feel Lasting Effects of Anonymous Attacks. 1 It detailed an online message board called AutoAdmit, wherein anonymous posters leave hundreds of comments every day about law school admissions, top schools, and law firms-along with sexualized and sexually aggressive comments about female law students, whose pictures are regularly posted for commenters to evaluate. All of the women quoted in the article asked to remain anonymous out of fear that the posts on the message board might have negative consequences for their employment prospects. The article hit a nerve-because I was one of the women whose pictures and personal information were posted on AutoAdmit

The Interstellar Medium White Paper

The interstellar medium is the engine room for galactic evolution. While much is known about the conditions within the ISM, many important areas regarding the formation and evolution of the various phases of the ISM leading to star formation, and its role in important astrophysical processes, remain to be explained. This paper discusses several of the fundamental science problems, placing them in context with current activities and capabilities, as well as the future capabilities that are needed to progress them in the decade ahead. Australia has a vibrant research community working on the interstellar medium. This discussion gives particular emphasis to Australian involvement in furthering their work, as part of the wider international endeavour. The particular science programs that are outlined in this White Paper include the formation of molecular clouds, the ISM of the Galactic nucleus, the origin of gamma-rays and cosmic rays, high mass star and cluster formation, the dense molecular medium, galaxy evolution and the diffuse atomic medium, supernova remnants, the role of magnetism and turbulence in the Galactic ecology and complex organic molecules in space

Improved Aedes aegypti mosquito reference genome assembly enables biological discovery and vector control

Female Aedes aegypti mosquitoes infect hundreds of millions of people each year with dangerous viral pathogens including dengue, yellow fever, Zika, and chikungunya. Progress in understanding the biology of this insect, and developing tools to fight it, has been slowed by the lack of a high-quality genome assembly. Here we combine diverse genome technologies to produce AaegL5, a dramatically improved and annotated assembly, and demonstrate how it accelerates mosquito science and control. We anchored the physical and cytogenetic maps, resolved the size and composition of the elusive sex-determining M locus, significantly increased the known members of the glutathione-S-transferase genes important for insecticide resistance, and doubled the number of chemosensory ionotropic receptors that guide mosquitoes to human hosts and egg-laying sites. Using high-resolution QTL and population genomic analyses, we mapped new candidates for dengue vector competence and insecticide resistance. We predict that AaegL5 will catalyse new biological insights and intervention strategies to fight this deadly arboviral vector