The role-share-influence of the posterior tibial slope on rupture of the anterior cruciate ligament

Background/Aim. Posterior tibial slope is one of the most citated factors wich cause rupture of the anterior cruciate ligament (ACL). The aim of this study was to determine the association of a greather posterior tibial slope on the lateral condyle, that is a lesser posterior tibial slope on the medial condyle, with ACL rupture. Methods. The patients were divided into two groups. The study group included the patients with chronic instability of the knee besause of a previous rupture of ACL. The control group included the patients with knee lesion, but without ACL rupture. Posterior tibial slope measuring was performed by sagittal MR slices supported by lateral radiograph of the knee. We measured posterior tibial slope on lateral and medial condyles of the tibia. Using these values we calculated an average posterior tibial slope as well as the difference between slopes on lateral and medial condyles. Results. Patients with ACL rupture have highly statistically significantly greather posterior tibial slope (p < 0.01) on lateral tibial condyle (7.1° : 4.5°) as well as statistically significantly lesser posterior tibial slope (p < 0.05) on medial tibial condyle (5.0° : 6.6°) than patients with intact ACL. Conclusion. Great posterior tibial slope on lateral tibial condyle associated with the small posterior tibial slope on the medial tibial condyle, that is a positive differentce between lateral and medial tibial condyles are factors wich may cause ACL rupture

Food waste as a nutrient source for the production of biopigment in Streptomyces sp. BV365

The genus Streptomyces has been studied for the vast secondary metabolite production, biological activity of crude extracts, as well as colouring properties on textile materials [1, 2]. Streptomyces sp. BV365 is a potent producer of yellow pigments, used to efficiently colour different natural textiles [3]. Utilization of food waste for bacterial growth and production of pigments and antifungals [4] could contribute to conversion of waste to valuable molecules, providing more economically acceptable and more eco-friendly generated biotherapeutics, enzymes and pigments.KNJIGA IZVODA: 9. simpozijum Hemija i zaštita životne sredine Kladovo, 4-7. jun 2023. BOOK OF ABSTRACTS : 9th Symposium Chemistry and Environmental Protection Kladovo, 4-7th June 202

キンセイ ジョウシ ユライ ノ トシ コウエン ニオケル シゼン リョクチ ノ セイタイテキ・シャカイテキ ヒョウカ

Supporting information for: [https://doi.org/10.1021/acs.organomet.5b00041]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/1746

Performanse krmnog sirka u funkciji cirkularne ekonomije

With a circular economy, biodegradable waste – plant biomass can be reused as: compost, for soil fertilization, and for biogas production, as an affordable bioenergy source. In this study, the productivity of two hybrids of fodder sorghum, grown in Ilandza, Serbia, was examined. The results showed that there was a statistically significant difference between the tested hybrids, for leaf mass. A positive highly significant correlation was found between plant mass and leaf mass. Fodder sorghum is a species with C4 photosynthesis, which has a high degree of photosynthetic activity and has a high production of organic matter resulting in high biomass yield. Sorghum is a productive and cost-effective plant suitable for production: animal feed, and for energy purposes.Cirkularnom ekonomijom, biorazgradivi otpad-biomasa biljaka može se koristiti i kao: kompost ali i za proizvodnju biogasa, kao pristupačan izvor bioenergije. U ovoj studiji ispitivana je produktivnost dva hibrida krmnog sirka, gajenog u Ilandži u Srbiji. Rezultati su pokazali da postoji statistički značajna razlika između testiranih hibrida. Pronađena je pozitivna značajna korelacija između mase biljke i mase lista. Krmni sirak je vrsta sa S4 fotosintezom, ima visok stepen fotosintetske aktivnosti i visoku proizvodnju organske materije što rezultira visokim prinosom biomase. Produktivna je vrsta pogodna za proizvodnju: hrane za životinje i energetske svrhe

Levels of Presepsin and Midregion-Proadrenomedullin in Septic Patients with End-Stage Renal Disease after Cardiovascular Surgery: 1-Year Follow Up Study

Background: Procalcitonin (PCT) is a marker for sepsis diagnosis, identification of bacterial infection and monitoring of antibiotic therapy. It has been shown that PCT is not a good choice in patients with hemodialysis. Therefore, we have explored two biomarkers: a) presepsin, and, b) midregion-proadrenomedullin (MR-proADM) in patients having End-Stage Renal Disease (ESRD). Patients and Methods: We prospectively enlisted 20 patients, who underwent cardiovascular surgery and had been on dialysis. The diagnosis of sepsis has been established clinically and confirmed by PCT. Blood samples were taken before and after dialysis. Additionally, plasma and sera of 10 healthy blood donors without any complications were used as controls. Results: Presepsin plasma concentrations (4368 ± 3088 vs. 694.1 ± 239.1 pg/mL) were significantly higher in patients with sepsis compared with controls (p0.05) with no significance between alive and deceased (p=0.53) patients. Adjustments have shown that the difference for MR-proADM level is due to the random sampling variability (p=0.989), whereas difference for presepsin remained highly significant (p<0.001). Conclusions: Our results indicate that the accuracy of new biomarkers is equal to that of PCT in patients with ESRD. Presepsin might be as good marker in repeated measurements, before and after dialysis, as it is PCT. © 2014 Maravic-Stojkovic V, et al

Biocompatible and degradable scaffolds based on 2-hydroxyethyl methacrylate, gelatin and poly(beta amino ester) crosslinkers

Gelatin hydrogels have great potential in regenerative medicine but their weak mechanical properties are a major drawback for the load-bearing applications, such as scaffolds for tissue engineering. To overcome this deficiency, novel biodegradable hydrogels with improved mechanical properties were prepared by combining gelatine with 2-hydroxyethyl methacrylate (HEMA), using a double network synthetic procedure. The first, superporous and mechanically strong network, was obtained by free radical polymerization of HEMA at cryogenic temperature, in the presence of gelatin. Degradable poly (beta-amino ester) (PBAE) macromers of different chemical composition or molecular weight were used as crosslinkers to introduce hydrolytically labile bonds in PHEMA. The second gelatin network was formed by crosslinking gelatin with glutaraldehyde. For comparison, a set of biodegradable PHEMA networks was obtained by polymerization of HEMA at cryogenic temperature. All samples were characterized revealing that mechanical strength, swelling behavior and degradation rate as well as high biocompatibility of new IPNs are in accordance with values required for scaffolds in tissue engineering applications and that tuning of these properties is accomplished by simply using different PBAE macromers

2-Hydroxyethyl Metahcrylate/Gelatin based Superporous Hydrogels for Tissue Regeneration

In this study, superporous hydrogels were synthesized by free radical polymerization of 2-hydroxyethyl methacrylate without and in the presence of gelatin. Highly porous hydrogel structures were obtained by two different techniques: using a gas blowing agent, sodium bicarbonate, and a cryogenic treatment followed by freeze-drying. After the gel synthesis, gelatin molecules were covalently immobilised onto PHEMA via glytaraldehyde activation. All samples were characterized for morphological, mechanical, swelling and antibacterial properties. The results obtained show that samples with gelatin show better properties in comparison with PHEMA samples, which make these materials highly attractive for developing hydrogel scaffolds for tissue regeneration

Bilateral sequential motor cortex stimulation and skilled task performance with non-dominant hand

Objective: To check whether bilateral sequential stimulation (BSS) of M1 with theta burst stimulation (TBS), using facilitatory protocol over non-dominant M1 followed by inhibitory one over dominant M1, can improve skilled task performance with non-dominant hand more than either of the unilateral stimulations do. Both, direct motor cortex (M1) facilitatory non-invasive brain stimulation (NIBS) and contralateral M1 inhibitory NIBS were shown to improve motor learning. Methods: Forty right-handed healthy subjects were divided into 4 matched groups which received either ipsilateral facilitatory (intermittent TBS [iTBS] over non-dominant M1), contralateral inhibitory (continuous TBS [cTBS] over dominant M1), bilateral sequential (contralateral cTBS followed by ipsilateral iTBS), or placebo stimulation. Performance was evaluated by Purdue peg-board test (PPT), before (T0), immediately after (T1), and 30 min after (T2) an intervention. Results: In all groups and for both hands, the PPT scores increased at T1 and T2 in comparison to T0, showing clear learning effect. However, for the target non-dominant hand only, immediately after BSS (at T1) the PPT scores improved significantly more than after either of unilateral interventions or placebo. Conclusion: M1 BSS TBS is an effective intervention for improving motor performance. Significance: M1 BSS TBS seems as a promising tool for motor learning improvement with potential uses in neurorehabilitation