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    Bartonella Clarridgeiae Bacteremia Detected In An Asymptomatic Blood Donor

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    Human exposure to Bartonella clarridgeiae has been reported only on the basis of antibody detection. We report for the first time an asymptomatic human blood donor infected with B. clarridgeiae, as documented by enrichment blood culture, PCR, and DNA sequencing.531352356Maggi, R.G., Duncan, A.W., Breitschwerdt, E.B., Novel chemically modified liquid medium that will support the growth of seven Bartonella species (2005) J Clin Microbiol, 43, pp. 2651-2655. , http://dx.doi.org/10.1128/JCM.43.6.2651-2655.2005Drummond, M.R., Pitassi, L.H., Lania, B.G., Dos Santos, S.R., Gilioli, R., Velho, P.E., Detection of Bartonella henselae in defibrinated sheep blood used for culture media supplementation (2011) Braz J Microbiol, 42, pp. 430-432. , http://dx.doi.org/10.1590/S1517-83822011000200003Altschul, S.F., Gish, W., Miller, W., Myers, E.W., Lipman, D.J., Basic local alignment search tool (1990) J Mol Biol, 215, pp. 403-410Dalton, M.J., Robinson, L.E., Cooper, J., Regnery, R.L., Olson, J.G., Childs, J.E., Use of Bartonella antigens for serologic diagnosis of cat-scratch disease at a national referral center (1995) Arch Intern Med, 155, pp. 1670-1676Breitschwerdt, E.B., Maggi, R.G., Chomel, B.B., Lappin, M.R., Bartonellosis: An emerging infectious disease of zoonotic importance to animals and human beings (2010) J Vet Emerg Crit Care (San Antonio), 20, pp. 8-30. , http://dx.doi.org/10.1111/j.1476-4431.2009.00496.xChamberlin, J., Laughlin, L.W., Romero, S., Solorzano, N., Gordon, S., Andre, R.G., Pachas, P., Watts, D., Epidemiology of endemic Bartonella bacilliformis: A prospective cohort study in a Peruvian mountain valley community (2002) J Infect Dis, 186, pp. 983-990. , http://dx.doi.org/10.1086/344054Maggi, R.G., Ericson, M., Mascarelli, P.E., Bradley, J.M., Breitschwerdt, E.B., Bartonella henselae bacteremia in a mother and son potentially associated with tick exposure (2013) Parasit Vectors, 6, p. 101. , http://dx.doi.org/10.1186/1756-3305-6-101Scott, M.A., McCurley, T.L., Vnencak-Jones, C.L., Hager, C., McCoy, J.A., Anderson, B., Collins, R.D., Edwards, K.M., Cat scratch disease: Detection of Bartonella henselae DNA in archival biopsies from patients with clinically, serologically, and histologically defined disease (1996) Am J Pathol, 149, pp. 2161-2167Slater, L.N., Welch, D.F., Min, K.W., Rochalimaea henselae causes bacillary angiomatosis and peliosis hepatis (1992) Arch Intern Med, 152, pp. 602-606Sander, A., Zagrosek, A., Bredt, W., Schiltz, E., Piemont, Y., Lanz, C., Dehio, C., Characterization of Bartonella clarridgeiae flagellin (FlaA) and detection of antiflagellin antibodies in patients with lymphadenopathy (2000) J Clin Microbiol, 38, pp. 2943-2948Kordick, D.L., Hilyard, E.J., Hadfield, T.L., Wilson, K.H., Steigerwalt, A.G., Brenner, D.J., Breitschwerdt, E.B., Bartonella clarridgeiae, a newly recognized zoonotic pathogen causing inoculation papules, fever, and lymphadenopathy (cat scratch disease) (1997) J Clin Microbiol, 35, pp. 1813-1818Margileth, A.M., Baehren, D.F., Chest-wall abscess due to cat-scratch disease (CSD) in an adult with antibodies to Bartonella clarridgeiae: Case report and review of the thoracopulmonary manifestations of CSD (1998) Clin Infect Dis, 27, pp. 353-357. , http://dx.doi.org/10.1086/514671Chomel, B.B., Mac Donald, K.A., Kasten, R.W., Chang, C.C., Wey, A.C., Foley, J.E., Thomas, W.P., Kittleson, M.D., Aortic valve endocarditis in a dog due to Bartonella clarridgeiae (2001) J Clin Microbiol, 39, pp. 3548-3554. , http://dx.doi.org/10.1128/JCM.39.10.3548-3554.2001Gillespie, T.N., Washabau, R.J., Goldschmidt, M.H., Cullen, J.M., Rogala, A.R., Breitschwerdt, E.B., Detection of Bartonella henselae and Bartonella clarridgeiae DNA in hepatic specimens from two dogs with hepatic disease (2003) J Am Vet Med Assoc, 222, pp. 47-51. , http://dx.doi.org/10.2460/javma.2003.222.47, 35Robinson, M.T., Hillman, T., Langton, D.A., Shaw, S.E., Bartonella clarridgeiae in a cat in the UK (2009) Vet Rec, 164, pp. 58-59. , http://dx.doi.org/10.1136/vr.164.2.58Sykes, J.E., Westropp, J.L., Kasten, R.W., Chomel, B.B., Association between Bartonella species infection and disease in pet cats as determined using serology and culture (2010) J Feline Med Surg, 12, pp. 631-636. , http://dx.doi.org/10.1016/j.jfms.2010.04.003Fouch, B., Coventry, S., A case of fatal disseminated Bartonella henselae infection (cat-scratch disease) with encephalitis (2007) Arch Pathol Lab Med, 131, pp. 1591-1594Boudebouch, N., Sarih, M., Beaucournu, J.C., Amarouch, H., Hassar, M., Raoult, D., Parola, P., Bartonella clarridgeiae, B. 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    Prevalence Of Dermatoses In The Primary Health Care System Of Campinas, São Paulo - Brazil [prevalência De Dermatoses Na Rede Básica De Saúde De Campinas, São Paulo - Brasil]

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    BACKGROUND - Skin lesions are often noted by the individuals bearing them, as well as by their relatives. There is a significant number of patients with skin complaints who search for medical care. OBJECTIVES - To determine the frequency of dermatological complaints and/or findings in users of the primary health care system of the city of Campinas, Brazil. METHODS - Five units were chosen by the Municipal Health Department to participate in this research. All the patients assisted by health professionals of these units were evaluated regarding the presence or absence of dermatological symptoms/ signals in a time period of twenty working days. RESULTS - The acquired data demonstrated that 358 (24.01%) out of 1,491 assisted patients displayed dermatological complaints and/or findings, with a greater prevalence among the younger patients. Of all the users assisted by health professionals who participated in the study and had their records adequately filled out, 9.98% sought the primary care unit primarily because of a dermatological complaint. CONCLUSIONS - These results, in accordance to those of similar surveys carried out in other countries, show the importance of the specialty for the performance of non-dermatologist physicians, pediatricians in particular, and provide elements for the discussion surrounding the curricular reform, concerning the amount of time dedicated to the teaching of dermatology. ©2007 by Anais Brasileiros de Dermatologia.825419424Carli, P., Giorgi, V., Palli, D., Maurichi, A., Mulas, P., Orlandi, C., Dermatologist detection and skin self-examination are associated with thinner melanomas - results from a survey of the Italian multidisciplinary group on melanoma (2003) Arch Dermatol, 139, pp. 607-612Lowell, B.A., Froelich, C.W., Federman, D.G., Kirsner, R.S., Dermatology in primary care: Prevalence and patient disposition (2001) J Am Acad Dermatol, 45, pp. 250-255Greco, P., Cafiero, P., Rípoli, M., Pierini, A.M., Proporción de patología dermatológica en la atención ambulatoria pediátrica. Dermatological diseases: Their proportion in ambulatory pediatric care (1997) Arch Argent Dermatol, 47, pp. 91-97(1991) Morbidity statistics from general practice: 4th National Study, pp. 54-56. , Royal College of General Practitioners, London: HMSO;, 92Julian, C.G., Dermatology in general practice (1999) Br J Dermatol, 141, pp. 518-520Solomon, B.A., Collins, R., Silverberg, N.B., Glass, A.T., Quality of care: Issue or oversight in health care reform? (1996) J Am Acad Dermatol, 34, pp. 601-607Bechelli LM, Haddad N, Pagnano PMG, Uthida-Tanaka AM, Zanin LC, Rocha dos Santos MRO, et al. Censo epidemiológico de lesões e afecções cutâneas em escolares de Ribeirão Preto, SP, Brasil. Arch Argent Dermatol. 1990;40:45-59Halpern, A., Are primary care physicians well trained in dermatology? (1995) Manag Care, 4, p. 49Kirsner, R.S., Federman, D.G., Lack of correlation between internists ability in dermatology and their patterns of treating patients with skin disease (1996) Arch Dermatol, 132, pp. 1043-1046Ciracy, E.W., Bland, C.J., Stoller, J.E., Graduate follow-up in the University of Minnesota affiliated hospitals residency training program in family practice and community health (1980) J Fam Pract, 11, pp. 719-730Chen, F.M., Dermatology referrals in an academic family medicine clinic (2001) South Med J, 94, pp. 475-477Barbarulo, A.M., Gavazza, S., Fontana, M.I., Berbari, S., Azcune, R., Evaluación de la capacidad diagnóstica de los médicos generales en dermatología. (2002) Arch Argent Dermatol, 52, pp. 111-115Pereira, L.B., Gontijo, B., Neonatal dermatoses of relevant medical significance: Their report in the newborn's file (1999) J Pediatr, 75, pp. 357-360Stephenson, A., From, L., Cohen, A., Tipping, J., Family physicians knowledge of malignant melanoma (1997) J Am Acad Dermatol, 37, pp. 953-957Whitaker-Worth, D.L., Susser, W.C., Grant-Kels, J.M., Clinical dermatologic education and the diagnostic acumen of medical students and primary care residents (1998) Int J Dermatol, 37, pp. 855-859Ramsay, D.L., Weary, P.E., Primary care in dermatology: Whose role should it be? (1996) J Am Acad Dermatol, 35, pp. 1005-1007Whited, J.D., Russell, P.H., Simel, D.L., Horner, R.D., Primary care clinicians performance for detecting actinic keratoses and skin cancer (1997) Arch Intern Med, 157, pp. 985-990Federman, D.G., Concato, J., Kirsner, R.S., Comparison of dermatologic diagnoses by primary care practitioners and dermatologists (1999) Arch Fam Med, 8, pp. 170-172Federman, D., Hogan, D., Taylor, J.R., Caralis, P., Kirsner, R.S., A comparison of diagnosis, evaluation, and treatment of patients with dermatologic disorders (1995) J Am Acad Dermatol, 32, pp. 726-72
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