Satisfaction Analysis In Men Presenting With Localized Prostate Cancer Treated With Radical Prostatectomy Or Radiotherapy: Psychological And Social Aspects [análisis De Satisfacción En Varones Que Presentaban Cáncer De Próstata Localizado Tratados Con Prostatectomía Radical O Radioterapia: Aspectos Psicológicos Y Sociales]

Objective: Analyze the treatment satisfaction and impact on patients with localized prostate cancer. Methods: One-hundred and eighty patients, with mean age of 60 years, were divided into three groups: group I - 100 patients submitted to radical retropubic prostatectomy (RRP), group II - 40 patients who underwent radiotherapy (RT), and group III - 40 healthy men. A questionnaire was applied to the groups to assess physical and psychological changes 18 months after treatment, The investigational tool was based on two questionnaires; first: SF-36 (Short Form Health Survey), second: FACT-P (Functional Assessment Cancer Therapy). Results: In group I, 70% never used pads, 5% presented with complete urinary incontinence, and 10% reported occasional stool leakage. In group II, 85% did not use pads and 5% reported two pads a day; 15% reported stool leakage or intestinal cramps. Sexual dysfunction was similar in both groups: 75% of the surgical group and 72.5% of the radiotherapy group reported erectile dysfunction, In the control group, 40% reported erectile dysfunction; 10% reported occasional stool leakage and none had changes regarding the overall treatment-related satisfaction, Seventy-eight percent of the RRP group and 77.5% of the RT group reported being happy respecting satisfaction with the accepted or chosen treatment, and affirmed that would choose it again. Conclusions: The assessment of treatment-related satisfaction determines the treatment tolerability, This study's results did not show any significant changes in this issue between both treatment modalities (p>0.05).324411416Macdonagh, R., Quality of life and its assessments in urology (1996) Br. J. Urol, 78 (4), pp. 485-496Litwin, M.S., Hays, R.D., Fink, A., Ganz, P.A., Leake, B., Leach, G.E., Quality of life outcomes in men treated for localized prostate cancer (1995) JAMA, 273 (2), pp. 129-135Fosså, S.D., Woehre, H., Kurth, K.H., Hetherington, J., Bakke, H., Rustad, D.A., Influence of urological morbidity on quality of life in patients with prostate cancer (1997) Eur Urol, 31 (SUPPL. 3), pp. 3-8Krongrad, A., Litwin, M.S., Lai, H., Lai, S., Dimensions of quality of life in prostate cancer (1998) J. Urol, 160 (3 PART 1), pp. 807-810Litwin, M.S., Lubeck, D.P., Henning, J.M., Flanders, S.C., Differences in urologist and patient assessments of health related quality of life in men with prostate cancer (1998) J Urol, 159 (6), pp. 1988-1991Clark, J.A., Rieker, P., Propert, J.K., Talcott, J.A., Changes in quality of life following treatment for early prostate cancer (1999) Urology, 53 (1), pp. 161-168MeCammon, K.A., Kolm, P., Main, B., Schelhammer, P.F., Comparative quality of life analysis after radical prostatectomy or external beam radiation for localized prostate cancer (1999) Urology, 54 (3), pp. 509-516Walsh, P.C., Lepor, H., Eggleston, J.C., Radical retropubic prostatectomy with preservation of sexual function: Anatomical and pathological considerations (1983) Prostate, 4 (5), pp. 473-476Walsh, P.C., Radical prostatectomy for localized prostate cancer provides durable cancer control with excellent quality of life: A structured debate (2000) J Urol, 163 (6), pp. 1166-1170Caffo, O., Fellini, G., Graffer, U., Luciani, L., Assessment of quality of life after radiotherapy (1996) B J Urol, 78 (4), pp. 557-563Esper, P., Mo, F., Chodak, G., Sinner, M., Cella, D., Pienta, K.J., Measuring quality of life in men with prostate cancer using the Functional Assessment of Cancer Therapy-Prostate Instrument (1997) Urology, 50 (6), pp. 920-928Krongrad, A., Perczek, R.E., Burke, M.A., Granville, L.J., Lai, H., Lai, S., Reliability of spanish translations of select urological quality of life instruments (1997) J Urol, 158 (2), pp. 493-498Brasilis, K.G., Santa-Cruz, C., Brickman, A.L., Soloway, M.S., Quality of life 12 months after radical prostatectomy (1995) B J Urol, 75 (1), pp. 48-53Smith, D.S., Carvalhal, G.F., Schneider, K., Krygiel, J., Yan, Y., Catalona, W.J., Quality of life outcomes for men with prostate cancer detected by screening (2000) Cancer, 88 (6), pp. 1454-1463Lim, A.J., Brandon, A.H., Fiedler, J., Brickman, A.L., Boyer, C.I., Raub Jr, W.A., Quality of life: Radical Prostatectomy versus Radiation Therapy for prostate cancer (1998) JAMA, 272, pp. 129-135Goluboff, E.T., Saidi, J.A., Mazer, S., Bagiella, E., Heitjan, D.F., Benson, M.C., Urinary incontinence after radical prostatectomy: The Columbia Experience (1998) J Urol, 159 (4), pp. 1276-1280Kaye, K.W., Creed, K.E., Wilson, G.J., D'Antuono, M., Dawkins, H.J., Urinary continence after radical retropubic prostatectomy. Analysis and synthesis of contributing factors: A unified concept (1997) B J Urol, 80 (3), pp. 444-501Twiss, C., Martin, S., Shore, R., Lepor, H., A continence index predicts the early return of urinary continence after radical retropubic prostatectomy (2000) J Urol, 164 (4), pp. 1241-1247Kerr, L.A., Zincke, H., Radical retropubic prostatectomy for prostate cancer in the elderly and young: Complications and prognosis (1994) Eur Urol, 25 (4), pp. 305-311Beard, C.J., Propert, K.J., Rieker, P.P., Clark, J.A., Kaplan, I., Kantoff, P.W., Complications after treatment with external-beam irradiation in early-stage prostate cancer patients: A prospective multiinstitutional outcomes study (1997) J Clin Oncol, 15 (1), pp. 223-229Geary, E.S., Dendinger, T.E., Freiha, E.S., Nerve sparing radical prostatectomy: A different view (1995) J Urol, 154 (1), pp. 145-149Litwin, M.S., Pasta, D.J., Yu, J., Stoddard, M.L., Flanders, S.C., Urinary function and bother after radical prostatectomy or radiation therapy for prostate cancer. A longitudinal, multivariate quality of life analysis from the Cancer of Prostate Strategic Urologic Research Endeavor (2000) J Urol, 164 (6), pp. 1973-1977Zelefsky, M.J., McKee, A.B., Lee, H., Leibel, S.A., Efficacy of oral sildenafil in patients with erectile dysfunction after radiotherapy for carcinoma of the prostate (1999) Urology, 53 (4), pp. 775-778Johannes, C.B., Araujo, A.B., Feldman, H.A., Derby, C.A., Kleinman, K.P., McKinlay, J.B., Incidence on erectile dysfunction in men 40 to 69 years old: Longitudinal results from the Massachusetts Male Aging Study (2000) J Urol, 163 (2), pp. 460-465Siegel, T., Moul, J.W., Sperak, M., Alvord, G.W., Costabile, R.A., The development of erectile dysfunction in men treated for prostate cancer (2001) J Urol, 165 (2), pp. 430-435Gralnek, D., Hunter, W., Dalkin, B.L., Differences in sexual function and quality of life after nerve sparing and non nerve sparing radical retropubic prostatectomy (2000) J Urol, 163, pp. 1166-1170Nehra, A., Goldstein, I., Sildenafil citrate (Viagra) after radical retropubic prostatectomy: Con (1999) Urology, 54 (4), pp. 587-58

Germinação de sementes e desenvolvimento de plântulas de moringa (Moringa oleifera Lam.) em função do peso da semente e do tipo de substrato Germination of seeds and seedling development of drumstick as a function of seed weight and substrate type

Moringa oleifera Lam. é uma espécie arbórea originária do noroeste indiano, cultivada graças ao seu valor alimentar, medicinal, industrial e no tratamento de água para o consumo humano. Os efeitos do peso de sementes e do substrato na germinação e desenvolvimento das plântulas foram determinados, sob condições de casa de vegetação (sombrite 50% com nebulização intermitente) em Fortaleza (CE), de 29/11 a 14/12/02. Os tratamentos constaram de arranjo fatorial 3x3 referente a três categorias de semente: pesadas (272,41 g/1000 sementes), médias (218,88 g/1000 sementes) e leves (177,07 g/1000 sementes); e três substratos: vermiculita; Plantmax® e uma mistura à base de solo esterilizado (S), húmus de minhoca (H) e pó de coco lavado (PC), na proporção de 2:1:1, dispostos em delineamento inteiramente casualizado com quatro repetições (24 sementes/repetição). Efetuou-se a semeadura das três classes de pesos de sementes em bandejas de isopor de 72 células contendo os substratos, avaliando-se a percentagem, velocidade e tempo médio de germinação, altura da plântula, massa seca da parte aérea e massa seca total. As sementes pesadas e médias apresentaram maior percentagem e velocidade de germinação do que as leves; as sementes pesadas proporcionaram plântulas mais vigorosas; no substrato Plantmax® e na mistura (S+H+PC) a percentagem e a velocidade de germinação foi superior à vermiculita; e as plântulas desenvolveram-se melhor no substrato Plantmax®.<br>To compensate the shortage of information on the influence of seed weight and substrate over the germination and seedling development of Moringa oleifera an experiment was conducted under greenhouse conditions (50% of natural light with intermittent nebulization) in Fortaleza, Ceará State, Brazil. The treatments consisted of a 3x3 factorial arrangement [three seed weights: heavy (272.41 g/1000 seeds); medium (218.88 g/1000 seeds) and light (177.07 g/1000 seeds) and three substrates: vermiculite; Plantmax® and a v/v 2:1:1 mixture based on sterilized soil (S) plus earthworm humus (H) and washed powdered coconut peels (PCP), respectively] disposed on an entirely randomized design with four repetitions (24 seeds/repetition). The three seed classes were sown in isopor trays with 72 cells containing the respective substrate. The percentage, rate and average time for germination; height and dry weight of total and aerial parts of the seedling were measured. Heavy and medium seeds presented a higher percentage and rate of germination than light seeds; heavy seeds yielded more vigorous seedlings; the commercial substrate Plantmax® and the mixture (S+H+PCP) allowed a higher percentage and germination rate than vermiculite; the seedlings showed a better development on the commercial substrate Plantmax®

Época de colheita e qualidade fisiológica de sementes de coentro produzidas no norte de Minas Gerais Harvest season and physiological quality of coriander seeds produced in the north of Minas Gerais

No presente trabalho, objetivou-se avaliar a época de colheita e a qualidade fisiológica de sementes de coentro produzidas no Norte de Minas Gerais. A primeira época de colheita das sementes foi realizada aos 15 dias após o florescimento pleno, quando aproximadamente 50% das plantas apresentavam flores. As demais colheitas foram realizadas de 7 em 7 dias, até as sementes atingirem 14,0% de umidade, fato que ocorreu na 6ª colheita. Imediatamente após cada colheita, as sementes foram avaliadas quanto ao teor de água, à germinação e ao vigor (testes de primeira contagem, emergência de plântulas e índice de velocidade de emergência). A maturidade fisiológica das sementes de coentro, cultivar Verdão, ocorre entre 42 a 44 dias após o florescimento, quando as sementes apresentam umidade em torno de 28,0%, podendo a colheita ser realizada até 50 dias após o florescimento, quando as sementes apresentavam 14,0% de umidade.<br>The present study aimed to evaluate the harvest season and physiological quality of coriander seeds produced in the North of Minas Gerais. The first season of harvest of the seeds was performed 15 days after full bloom, when approximately 50% of plants had flowers. The other crops were carried out 7 in 7 days, until the seeds reach 14,0% moisture, a fact that occurred in the 6th harvest. Immediately after each harvest, the seeds were evaluated for water content, germination and vigor tests (first count, seedling emergence and emergence speed index). The physiological maturity of coriander seeds, cultivate Verdão, occurs between 42 to 44 days after flowering, when the seeds had humidity around 28,0% at physiological maturity, the harvest may be held until 50 days after flowering, when seeds had 14,0% humidity

Informações fenotípicas e marcadores microssatélites de QTL na escolha de populações segregantes de feijoeiro Choice of common bean segregant populations using phenotypic information and QTL microsatellite markers

O objetivo deste trabalho foi selecionar populações segregantes de feijoeiro promissoras para a produtividade de grãos e com polimorfismo para marcadores microssatélites ligados a QTL relacionados previamente à produtividade de grãos. Foram utilizadas 49 linhagens, avaliadas em dois experimentos em látice triplo. Sete linhagens foram selecionadas e intercruzadas no esquema dialélico e também genotipadas com 24 marcadores microssatélites ligados a QTL previamente identificados. As populações foram avaliadas em blocos completos casualizados, com três repetições. Foram observadas diferenças significativas entre as capacidades gerais (CGC) e específicas de combinação (CEC) e os efeitos não-aditivos foram mais pronunciados. As linhagens RC1-10 e Z-9 se destacaram em razão das elevadas estimativas de g i. Entre os microssatélites, 25% foram polimórficos. Foram selecionadas quatro populações para a seleção de famílias com base na avaliação das linhagens, na análise dialélica e no polimorfismo entre os marcadores microssatélites. Destacou-se a população RC1-10 x Z-9, formada por genitores de alta CGC, com alta média e CEC e ainda grãos do tipo Carioca. Considerando o baixo número de microssatélites polimórficos obtidos nas populações, pode-se concluir haver necessidade de utilização de maior número de microssatélites ligados a QTL da produção de grãos.<br>The objective of this work was to select promising common bean segregant populations for grain yield and polymorphic to microsatellite markers for grain yield QTL previously identified. Fourty nine lines were utilized and evaluated in two field trials in a triple lattice. Seven lines were selected and intercrossed in a diallel scheme and genotyped with 24 single sequence repeat (SSR) markers associated to grain yield QTL previously identified. Populations were evaluated in a randomized block design with three replications. Significant differences in the general and specific combining ability were observed, and the non-additive effects were highest. The outstanding lines were RC1-10 and Z-9 due to the highest g i values. Twenty five percent of the markers were polymorphic. Four populations were chosen for selecting families based on the line evaluations, the diallel analysis and the polymorphism of SSR markers. Among the segregant populations, RC1-10 x Z-9 is remarkable for having high CEC, high grain yield of the Carioca type, and their parents expressed high CGC. Considering the low number of polymorphic microsatellite markers in each population, it is necessary to use higher number of microsatellite markers associated to grain yield QTL