72 research outputs found
Does the continuation of low-dose acetylsalicylic acid during the perioperative period of thyroidectomy increase the risk of cervical haematoma? A 1-year experience of two Italian centers
Background: A growing number of patients taking antiplatelet drugs, mainly low-dose acetylsalicylic acid (ASA) (75â150â
mg/day), for primary or secondary prevention of thrombotic events, are encountered in every field of surgery. While the bleeding risk due to the continuation of these medications during the perioperative period has been adequately investigated in several surgical specialties, in thyroid surgery it still needs to be clarified. The main aim of this study was to assess the occurrence of cervical haematoma in patients receiving low-dose acetylsalicylic acid, specifically ASA 100â
mg/day, during the perioperative period of thyroidectomy.
Methods: Patients undergoing thyroidectomy in two high-volume thyroid surgery centers in Italy, between January 2021 and December 2021, were retrospectively analysed. Enrolled patients were divided into two groups: those not taking ASA were included in Group A, while those receiving this drug in Group B. Univariate analysis was performed to compare these two groups. Moreover, multivariate analysis was employed to evaluate the use of low-dose ASA as independent risk factor for cervical haematoma.
Results: A total of 412 patients underwent thyroidectomy during the study period. Among them, 29 (7.04%) were taking ASA. Based on the inclusion criteria, 351 patients were enrolled: 322 were included in Group A and 29 in Group B. In Group A, there were 4 (1.24%) cervical haematomas not requiring surgical revision of haemostasis and 4 (1.24%) cervical haematomas requiring surgical revision of haemostasis. In Group B, there was 1 (3.45%) cervical haematoma requiring surgical revision of haemostasis. At univariate analysis, no statistically significant difference was found between the two groups in terms of occurrence of cervical haematoma, nor of the other early complications of thyroidectomy. At multivariate analysis, the use of low-dose ASA did not prove to be an independent risk factor for cervical haematoma.
Conclusions: Based on our findings, we believe that in patients receiving this drug, either for primary or secondary prevention of thrombotic events, its discontinuation during the perioperative period of thyroidectomy is not necessary
An X-ray polarimeter for hard X-ray optics
Development of multi-layer optics makes feasible the use of X-ray telescope
at energy up to 60-80 keV: in this paper we discuss the extension of
photoelectric polarimeter based on Micro Pattern Gas Chamber to high energy
X-rays. We calculated the sensitivity with Neon and Argon based mixtures at
high pressure with thick absorption gap: placing the MPGC at focus of a next
generation multi-layer optics, galatic and extragalactic X-ray polarimetry can
be done up till 30 keV.Comment: 12 pages, 7 figure
POLARIX: a pathfinder mission of X-ray polarimetry
Since the birth of X-ray astronomy, spectral, spatial and timing observation
improved dramatically, procuring a wealth of information on the majority of the
classes of the celestial sources. Polarimetry, instead, remained basically
unprobed. X-ray polarimetry promises to provide additional information
procuring two new observable quantities, the degree and the angle of
polarization. POLARIX is a mission dedicated to X-ray polarimetry. It exploits
the polarimetric response of a Gas Pixel Detector, combined with position
sensitivity, that, at the focus of a telescope, results in a huge increase of
sensitivity. Three Gas Pixel Detectors are coupled with three X-ray optics
which are the heritage of JET-X mission. POLARIX will measure time resolved
X-ray polarization with an angular resolution of about 20 arcsec in a field of
view of 15 arcmin 15 arcmin and with an energy resolution of 20 % at 6
keV. The Minimum Detectable Polarization is 12 % for a source having a flux of
1 mCrab and 10^5 s of observing time. The satellite will be placed in an
equatorial orbit of 505 km of altitude by a Vega launcher.The telemetry
down-link station will be Malindi. The pointing of POLARIX satellite will be
gyroless and it will perform a double pointing during the earth occultation of
one source, so maximizing the scientific return. POLARIX data are for 75 % open
to the community while 25 % + SVP (Science Verification Phase, 1 month of
operation) is dedicated to a core program activity open to the contribution of
associated scientists. The planned duration of the mission is one year plus
three months of commissioning and SVP, suitable to perform most of the basic
science within the reach of this instrument.Comment: 42 pages, 28 figure
A photoelectric polarimeter for XEUS: a new window in x-ray sky
XEUS is a large area telescope aiming to rise X-ray Astronomy to the level of
Optical Astronomy in terms of collecting areas. It will be based on two
satellites, locked on a formation flight, one with the optics, one with the
focal plane. The present design of the focal plane foresees, as an auxiliary
instrument, the inclusion of a Polarimeter based on a Micropattern Chamber. We
show how such a device is capable to solve open problems on many classes of
High Energy Astrophysics objects and to use X-ray sources as a laboratory for a
substantial progress on Fundamental Physics.Comment: 12 pages, 7 figure
POLARIX: a small mission of x-ray polarimetry
X-Ray Polarimetry can be now performed by using a Micro Pattern Gas Chamber
in the focus of a telescope. It requires large area optics for most important
scientific targets. But since the technique is additive a dedicated mission
with a cluster of small telescopes can perform many important measurements and
bridge the 40 year gap between OSO-8 data and future big telescopes such as
XEUS. POLARIX has been conceived as such a pathfinder. It is a Small Satellite
based on the optics of JET-X. Two telescopes are available in flight
configuration and three more can be easily produced starting from the available
superpolished mandrels. We show the capabilities of such a cluster of
telescopes each equipped with a focal plane photoelectric polarimeter and
discuss a few alternative solutions.Comment: 9 pages, 5 figure
AGILE TGFS AND GLOBAL LIGHTNING ACTIVITY
[1] The AGILE satellite detects Terrestrial Gamma-ray Flashes (TGFs) in the 0.35â100 MeV energy range using its Mini-Calorimeter (MCAL) instrument with an average detection rate of 10 TGFs/month. Thanks to its Low Earth Orbit with only 2.5 degree of inclination, AGILE guarantees an unprecedented exposure above the equator, where both lightning activity and TGF detection peak. Here we report the comparison between the AGILE TGFs detected between March 2009 and February 2010 and full climatology lightning worldwide distribution based on satellite optical observations from LIS (Lightning Imaging Sensor) and OTD (Optical Transient Detector) instruments. This approach is complementary to the one-to-one TGF/lightning correlations by ground-based sferics measurements. Based on mono and bi-dimensional Kolmogorov-Smirnov tests, we show that the AGILE TGFs and time-averaged global lightning in the equatorial area are not drawn from the same distribution. However, we find significant regional differences in the degree of correlation as well as in the TGF/lightning ratio. In the case of south east Asia we find a 87% probability for the TGF and lightning being samples of the same distribution. This result supports the idea that the physical conditions at play in TGF generation can have strong geographical and climatological modulation. Based on the assumption that the observed range of TGF/flash ratio holds at all latitudes we can estimate a global rate of â 220 Ă· 570 TGFs per day. The observed TGF/flash geographical modulation as well as the TGF global rate estimate are in agreement with previous observations
TGF DETECTION BY AGILE
We report the detection by the Astrorivelatore Gamma a Immagini Leggero (AGILE) satellite of terrestrial gamma ray flashes (TGFs) obtained with the minicalorimeter (MCAL) detector operating in the ..
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