Information Technology, Diffusion, and the Human Services Industry

There has been substantial research in the diffusion of innovation as applied to information systems. For nearly twenty years, this research has relied mostly on IS-process models and IS-factor models. IS-process models consider the typical stages of incorporation of information technologies (IT) into the organization (Gibson and Nolan, 1974; McKenney and McFarlan, 1982). IS-factor models examine the various technological, organizational, and external environmental characteristics that relate to IS-diffusion within an enterprise. Kwon & Zmud (1987) and Fichman (1992) provide extensive reviews of earlier factors research, and outline several factor areas that need further exploration. Current literature includes a third modelthe consequencemodel for IT diffusion. In this model, the extent of IT diffusion serves as an intervening variable, with organizational consequences serving as the dependent variable (Ferns & Palley, 1995). The literature on IT diffusion provides little information about IT diffusion innonbusiness sectors. There have been some IT diffusion studies that include public administration areas (Bretschneider & Wittmer, 1993), education (Trachtman, Spirek, Sparks & Stohl, 1991) and healthcare systems (Palley, 1991). Nonetheless, there has beenlittle investigation of IT diffusion on other nonprofit sectors. This research addresses problems in applying existing theory on IT diffusion to the Human Services sector, and in Direct Service Providers (DSPs), as defined below, in particular. One, thereare few studies in the literature that even describe the extent of IT diffusion in DSPs. Second, most factorsmodel studies operationalize the factor constructs in the context of business organizations. The metrics used in these studies may not be appropriate for DSPs. Finally, studies of the consequences of IT diffusion are rare, and this is particularly true of IT diffusion in DSPs. The lack of data on these consequences creates a vacuum in which potential innovators may have only subjective information on which to base implementation decisions. In such cases, potential innovators may either inappropriately implement or resist IT innovations. This research considers DSPs in terms of standing ITdiffusion research, and indicates probable reasons that have contributed to low levels of diffusion. We examine DSP structural characteristics, contrast the information needs of this sector to business sectors, and project what IT diffusion theory indicates within this industry. This research also will weigh the opportunity costs associated with the lack of IT/DSP diffusion research and will suggest significant areas where more knowledge of IT diffusion would have the greatest potential utilit

Columbia River Rhyolites: Age-Distribution Patterns and Their Implications for Arrival, Location, and Dispersion of Continental Flood Basalt Magmas in the Crust

Columbia River province magmatism is now known to include abundant and widespread rhyolite centers even though the view that the earliest rhyolites erupted from the McDermitt Caldera and other nearby volcanic fields along the Oregon–Nevada state border has persisted. Our study covers little-studied or unknown rhyolite occurrences in eastern Oregon that show a much wider distribution of older centers. With our new data on distribution of rhyolite centers and ages along with literature data, we consider rhyolites spanning from 17.5 to 14.5 Ma of eastern Oregon, northern Nevada, and western Idaho to be a direct response to flood basalts of the Columbia River Basalt Group (CRBG) and collectively categorize them as Columbia River Rhyolites. The age distribution patterns of Columbia River Rhyolites have implications for the arrival, location, and dispersion of flood basalt magmas in the crust. We consider the period from 17.5 to 16.4 Ma to be the waxing phase of rhyolite activity and the period from 15.3 to 14.5 Ma to be the waning phase. The largest number of centers was active between 16.3–15.4 Ma. The existence of crustal CRBG magma reservoirs beneath rhyolites seems inevitable, and hence, rhyolites suggest the following. The locations of centers of the waxing phase imply the arrival of CRBG magmas across the distribution area of rhyolites and are thought to correspond to the thermal pulses of arriving Picture Gorge Basalt and Picture-Gorge-Basalt-like magmas of the Imnaha Basalt in the north and to those of Steens Basalt magmas in the south. The earlier main rhyolite activity phase corresponds with Grande Ronde Basalt and evolved Picture Gorge Basalt and Steens Basalt. The later main phase rhyolite activity slightly postdated these basalts but is contemporaneous with icelanditic magmas that evolved from flood basalts. Similarly, centers of the waning phase span the area distribution of earlier phases and are similarly contemporaneous with icelanditic magmas and with other local basalts. These data have a number of implications for long-held notions about flood basalt migration through time and the age-progressive Snake River Plain Yellowstone rhyolite trend. There is no age progression in rhyolite activity from south-to-north, and this places doubt on the postulated south-to-north progression in basalt activity, at least for main-phase CRBG lavas. Furthermore, we suggest that age-progressive rhyolite activity of the Snake River Plain–Yellowstone trend starts at ~12 Ma with activity at the Bruneau Jarbidge center, and early centers along the Oregon–Nevada border, such as McDermitt, belong to the early to main phase rhyolites identified here

General anaesthetic and airway management practice for obstetric surgery in England: a prospective, multi-centre observational study

There are no current descriptions of general anaesthesia characteristics for obstetric surgery, despite recent changes to patient baseline characteristics and airway management guidelines. This analysis of data from the direct reporting of awareness in maternity patients' (DREAMY) study of accidental awareness during obstetric anaesthesia aimed to describe practice for obstetric general anaesthesia in England and compare with earlier surveys and best-practice recommendations. Consenting patients who received general anaesthesia for obstetric surgery in 72 hospitals from May 2017 to August 2018 were included. Baseline characteristics, airway management, anaesthetic techniques and major complications were collected. Descriptive analysis, binary logistic regression modelling and comparisons with earlier data were conducted. Data were collected from 3117 procedures, including 2554 (81.9%) caesarean deliveries. Thiopental was the induction drug in 1649 (52.9%) patients, compared with propofol in 1419 (45.5%). Suxamethonium was the neuromuscular blocking drug for tracheal intubation in 2631 (86.1%), compared with rocuronium in 367 (11.8%). Difficult tracheal intubation was reported in 1 in 19 (95%CI 1 in 16-22) and failed intubation in 1 in 312 (95%CI 1 in 169-667). Obese patients were over-represented compared with national baselines and associated with difficult, but not failed intubation. There was more evidence of change in practice for induction drugs (increased use of propofol) than neuromuscular blocking drugs (suxamethonium remains the most popular). There was evidence of improvement in practice, with increased monitoring and reversal of neuromuscular blockade (although this remains suboptimal). Despite a high risk of difficult intubation in this population, videolaryngoscopy was rarely used (1.9%)

The Littlefield Rhyolite and Associated Mafic Lavas: Bimodal Volcanism of the Columbia River Magmatic Province, with Constraints on Age and Storage Sites of Grande Ronde Basalt Magmas

We present data that distinguishes the long-known Littlefield Rhyolite of eastern Oregon (northwestern United States) into two distinct, voluminous, Snake River–type, high-temperature rhyolite lava packages that erupted in short sequence overk.y., with minimum volumes of 100 and 150 km3 respectively, contemporaneous with flood basalt volcanism of the Grande Ronde Basalt phase of the Columbia River Basalt Group. Contemporaneity of rhyolites with flood basalts is exceptionally demonstrated within the Malheur Gorge by intercalated mafic units belonging to the Grande Ronde Basalt that are stratigraphically constrained by underlying and overlying Littlefield Rhyolite flows, and the underlying Dinner Creek Tuff (unit 1). Our new ages of 16.11 Ma and 16.02 Ma for the lower and upper Littlefield Rhyolite, respectively, provide a narrow age constraint on the controversial lower age of Grande Ronde Basalt volcanism. Petrological data on local, intercalated Fe‑rich andesitic (icelanditic) lavas provide further evidence for coeval existence of rhyolitic and mafic magmas, and additionally provide location evidence for storage sites of Grande Ronde Basalt magmas. Based on these data in addition to similar data on the nearby Dinner Creek Tuff rhyolite center, as well as the locations of other rhyolite centers that fall within the same period of intense rhyolite volcanism of ca. 16.1 Ma, we infer that Grande Ronde Basalt crustal magma reservoirs were widespread in this area of eastern Oregon. We further infer that the main eruptions of stored flood basalt magmas followed the magmas’ lateral transport from these reservoirs to the well-known dike swarms located at the periphery of the rhyolite distribution area where local eruptions of rhyolites are notably absent. Our study highlights the interplay of mafic and crustally derived rhyolite magmas, with implications for other continental flood basalt provinces that are less well preserved than the Columbia River Basalt province

CD-ROM Search Techniques of Novice End-Users: Is the English-as-a -Second-Language Student at a Disadvantage?

published or submitted for publicatio

Columbia River Rhyolites: Age-Distribution Patterns and Their Implications for Arrival, Location, and Dispersion of Continental Flood Basalt Magmas in the Crust

Columbia River province magmatism is now known to include abundant and widespread rhyolite centers even though the view that the earliest rhyolites erupted from the McDermitt Caldera and other nearby volcanic fields along the Oregon–Nevada state border has persisted. Our study covers little-studied or unknown rhyolite occurrences in eastern Oregon that show a much wider distribution of older centers. With our new data on distribution of rhyolite centers and ages along with literature data, we consider rhyolites spanning from 17.5 to 14.5 Ma of eastern Oregon, northern Nevada, and western Idaho to be a direct response to flood basalts of the Columbia River Basalt Group (CRBG) and collectively categorize them as Columbia River rhyolites. The age distribution patterns of Columbia River rhyolites have implications for the arrival, location, and dispersion of flood basalt magmas in the crust. We consider the period from 17.5 to 16.4 Ma to be the waxing phase of rhyolite activity and the period from 15.3 to 14.5 Ma to be the waning phase. The largest number of centers was active between 16.3–15.4 Ma. The existence of crustal CRBG magma reservoirs beneath rhyolites seems inevitable, and hence, rhyolites suggest the following. The locations of centers of the waxing phase imply the arrival of CRBG magmas across the distribution area of rhyolites and are thought to correspond to the thermal pulses of arriving Picture Gorge Basalt and Picture-Gorge-Basalt-like magmas of the Imnaha Basalt in the north and to those of Steens Basalt magmas in the south. The earlier main rhyolite activity phase corresponds with Grande Ronde Basalt and evolved Picture Gorge Basalt and Steens Basalt. The later main phase rhyolite activity slightly postdated these basalts but is contemporaneous with icelanditic magmas that evolved from flood basalts. Similarly, centers of the waning phase span the area distribution of earlier phases and are similarly contemporaneous with icelanditic magmas and with other local basalts. These data have a number of implications for long-held notions about flood basalt migration through time and the age-progressive Snake River Plain Yellowstone rhyolite trend. There is no age progression in rhyolite activity from south-to-north, and this places doubt on the postulated south-to-north progression in basalt activity, at least for main-phase CRBG lavas. Furthermore, we suggest that age-progressive rhyolite activity of the Snake River Plain–Yellowstone trend starts at ~12 Ma with activity at the Bruneau Jarbidge center, and early centers along the Oregon–Nevada border, such as McDermitt, belong to the early to main phase rhyolite identified here

Osteoporosis and lactose intolerance

<p>A) Recombination pattern (according to jpHMM) of the URF_0206 (15228_1_49) discovered in the ICONIC dataset and the sequences L39106 and AF064699, prototypes of the recombinants CRF02_AG and CRF06_cpx, respectively. B) Bootscanning analysis of the URF_0206 performed using SimPlot and diagram showing the definitive recombination pattern.</p

Caveolin-3 Promotes Nicotinic Acetylcholine Receptor Clustering and Regulates Neuromuscular Junction Activity

This study identifies caveolin-3 as a key component of the signaling machinery that regulates clustering of the nicotinic acetylcholine receptor and controls neuromuscular junction function