Autonomous path following and emergency braking control for intelligent vehicles using low cost devices

Proceeding of: 15th International Symposium on Advanced Vehicle Control (AVEC '22), September 12-15, 2022, Kanagawa, JapanThe novelty of this paper is an Event-Triggered LPV Output-Feedback H∞ controller that generates a steering control signal to follow the road, an acoustic sensor based AEB-P system which avoids vehicle collision with pedestrians and a speed controller based on the curvature of the path. The validation of the proposed system is done through simulation tests with CarSim®This work was supported by the FEDER/Ministry of Science and Innovation - Agencia Estatal de Investigación (AEI) of the Government of Spain through the project [RTI2018-095143-B-C21]

Simultaneous Estimation of Vehicle Sideslip and Roll Angles Using an Integral-Based Event-Triggered Hinfinity Observer Considering Intravehicle Communications

In recent years, several technological advances have been incorporated into vehicles to ensure their safety and ride comfort. Most of these driver-assistance technologies aim to prevent skidding, whereas less attention has been paid to the avoidance of other dangerous situations such as a rollover. Since knowledge of slip and roll angles is critical to the control and safety of vehicle handling, their estimation remains of great interest when addressing emerging constraints in modern technologies involving networked communications and distributed computing. This paper presents an integral-based event-triggered H ¿ observer to simultaneously estimate the sideslip and roll angles, considering intravehicle communications with a networked-induced delay. As the longitudinal velocity and tire cornering stiffness of a vehicle can vary significantly during driving and have a strong influence on vehicle lateral stability, these time-varying parameter uncertainties are considered in the design of the observer. The simulation and experimental results demonstrate the effectiveness of the proposed observer.This work was supported by the Agencia Estatal de Investigacion (AEI) of the Ministry of Science and Innovation of the Government of Spain through the project RTI2018-095143-B-C2

Simultaneous Estimation of Vehicle Sideslip and Roll Angles Using an Event-Triggered-Based IoT Architecture

In recent years, there has been a significant integration of advanced technology into the automotive industry, aimed primarily at enhancing safety and ride comfort. While a notable proportion of these driver-assist systems focuses on skid prevention, insufficient attention has been paid to addressing other crucial scenarios, such as rollovers. The accurate estimation of slip and roll angles plays a vital role in ensuring vehicle control and safety, making these parameters essential, especially with the rise of modern technologies that incorporate networked communication and distributed computing. Furthermore, there exists a lag in the transmission of information between the various vehicle systems, including sensors, actuators, and controllers. This paper outlines the design of an IoT architecture that accurately estimates the sideslip angle and roll angle of a vehicle, while addressing network transmission delays with a networked control system and an event-triggered communication scheme. Experimental results are presented to validate the performance of the IoT architecture proposed. The event-triggered scheme of the IoT solution is used to decrease data transmission and prevent network overload.Funding. Grant [ PID2022-136468OB-I00 ] funded by MCIN/AEI/ 10.13039/501100011033 and by “ERDF A way of making Europe”

Whole-Body MRI and Ethnic Differences in Adipose Tissue and Skeletal Muscle Distribution in Overweight Black and White Adolescent Boys

It is unclear whether ethnic differences exist in adipose tissue (AT) and skeletal muscle (SM) distribution in black and white youth. Investigation into the pattern of AT and SM distribution in black versus white youth may provide insight into the previously reported health disparities between these ethnicities. Therefore, we examined total and regional AT and SM in overweight black and white boys. The study sample included overweight black (n = 19) and white (n = 21) boys (11–18 yr, BMI ≥ 85th) whose body composition was evaluated using whole-body MRI. Despite similar age, Tanner stage, and BMI, black boys had significantly (P < .05) less visceral AT than white boys and more (P < .05) total and lower-body subcutaneous AT (SAT) in both absolute (kg) and relative (%) terms. There was a main effect (P < .05) of ethnicity on the relationship between total and regional AT, such that for a given amount of total body AT (kg), black boys had a greater (P < .05) lower-body SAT and less visceral AT than their white peers. For a given amount of total SM, black boys had more (P < .05) SM in the thigh. Compared with overweight white boys, overweight black boys have less visceral fat, more subcutaneous fat, and more thigh skeletal muscle

Gene Expression Space Shapes the Bioprocess Trade-Offs among Titer, Yield and Productivity

[EN] Optimal gene expression is central for the development of both bacterial expression systems for heterologous protein production, and microbial cell factories for industrial metabolite production. Our goal is to fulfill industry-level overproduction demands optimally, as measured by the following key performance metrics: titer, productivity rate, and yield (TRY). Here we use a multiscale model incorporating the dynamics of (i) the cell population in the bioreactor, (ii) the substrate uptake and (iii) the interaction between the cell host and expression of the protein of interest. Our model predicts cell growth rate and cell mass distribution between enzymes of interest and host enzymes as a function of substrate uptake and the following main lab-accessible gene expression-related characteristics: promoter strength, gene copy number and ribosome binding site strength. We evaluated the differential roles of gene transcription and translation in shaping TRY trade-offs for a wide range of expression levels and the sensitivity of the TRY space to variations in substrate availability. Our results show that, at low expression levels, gene transcription mainly defined TRY, and gene translation had a limited effect; whereas, at high expression levels, TRY depended on the product of both, in agreement with experiments in the literature.This research was partially supported by grants MINECO/AEI, EU DPI2017-82896-C21-R 662 and MICINN/AEI, EU PID2020-117271RB-C21. F.N.S.-N. thanks the UPV grant number PAID-01-2017.Santos-Navarro, FN.; Boada-Acosta, YF.; Vignoni, A.; Picó, J. (2021). Gene Expression Space Shapes the Bioprocess Trade-Offs among Titer, Yield and Productivity. Applied Sciences. 11(13):1-17. https://doi.org/10.3390/app11135859S117111

RBS and Promoter Strengths Determine the Cell-Growth-Dependent Protein Mass Fractions and Their Optimal Synthesis Rates

[EN] Models of gene expression considering host-circuit interactions are relevant for understanding both the strategies and associated trade-offs that cell endogenous genes have evolved and for the efficient design of heterologous protein expression systems and synthetic genetic circuits. Here, we consider a small-size model of gene expression dynamics in bacterial cells accounting for host-circuit interactions due to limited cellular resources. We define the cellular resources recruitment strength as a key functional coefficient that explains the distribution of resources among the host and the genes of interest and the relationship between the usage of resources and cell growth. This functional coefficient explicitly takes into account lab-accessible gene expression characteristics, such as promoter and ribosome binding site (RBS) strengths, capturing their interplay with the growth-dependent flux of available free cell resources. Despite its simplicity, the model captures the differential role of promoter and RBS strengths in the distribution of protein mass fractions as a function of growth rate and the optimal protein synthesis rate with remarkable fit to the experimental data from the literature for Escherichia coli. This allows us to explain why endogenous genes have evolved different strategies in the expression space and also makes the model suitable for model-based design of exogenous synthetic gene expression systems with desired characteristics.This work was partially supported by grants MINECO/AEI, EU DPI2017-82896-C2-1-R, and MCIN/AEI/10.13039/501100011033 grant number PID2020-117271RB-C21. F.N.S.-N. is grateful to grant PAID-01-2017 (Universitat Politecnica de Valencia). The authors are very grateful to the anonymous reviewers for their comprehensive and in-depth reviews.Santos-Navarro, FN.; Vignoni, A.; Boada-Acosta, YF.; Picó, J. (2021). RBS and Promoter Strengths Determine the Cell-Growth-Dependent Protein Mass Fractions and Their Optimal Synthesis Rates. ACS Synthetic Biology. 10(12):3290-3303. https://doi.org/10.1021/acssynbio.1c0013132903303101

Programa de educación y fomento de la adherencia al tratamiento dirigido a los usuarios de los nuevos anticoagulantes orales

Introducción: Los principales anticoagulantes directos permitidos y regulados en España son Rivaroxabán (Xarelto®), Apixabán (Eliquis®) y Dabigatrán etexilato (Pradaxa®). Estos fármacos, según sus características, no sólo se aproximan al anticoagulante ideal sino que mejoran la seguridad y eficacia de los pacientes y pueden suponer un ahorro a largo plazo tanto para el Sistema Nacional de Salud como para el individuo. En España, el ritmo de introducción es inferior al del resto de Europa aunque se estima que en los próximos cinco años se usen en al menos el 50% de los pacientes con fibrilación auricular por lo que se deben elaborar programas de salud y guías de autocuidado para abordar este nuevo tratamiento. Objetivo: Elaborar un programa de educación y fomento de la adherencia al tratamiento para pacientes que se inician con los nuevos anticoagulantes orales (NACO). Metodología: Se realizó una búsqueda bibliográfica en las principales bases de datos (Dialnet, Pubmed y Science direct y Google académico), además de consultar distintas guías elaboradas por organizaciones nacionales e internacionales, revistas electrónicas y páginas webs. Conclusiones: Gracias a la difusión de una educación sanitaria dirigida especialmente a los usuarios de los nuevos anticoagulantes orales, los usuarios ganan en comodidad e independencia mejorando su calidad de vida y aumentando su adherencia al tratamiento

Abordaje de la ansiedad a partir de un programa de educación para la salud

Introducción: Actualmente la ansiedad es un problema muy extendido entre la población adulta española debido a los hábitos de vida y el estrés diario. Habitualmente la población utiliza fármacos para disminuir la ansiedad. Sin embargo una correcta educación sobre la ansiedad y las diversas técnicas para abordarla disminuirían la prevalencia de la ansiedad y mejoraría el autocuidado del paciente. Objetivos: El objetivo principal de este trabajo es elaborar un programa de salud en el cual se expliquen diversas técnicas utilizadas para disminuir y manejar la ansiedad además, además contiene una sesión de autocuidados. Metodología: La realización del programa tiene un carácter descriptivo y se basa en una búsqueda de artículos de carácter científico en diferentes bases de datos, libros y páginas web. Desarrollo: El programa irá dirigido a la población adulta entre 30 y 45 años de Valdespartera. El programa constará de tres sesiones en las que se contará con la colaboración de dos profesionales expertos en el tema a exponer, en estas sesiones daremos una pequeña muestra de las terapias propuestas. Conclusiones: El conocimiento de otras terapias además de la farmacológica invita a los pacientes a probarlas pudiendo disminuir el consumo de fármacos y la dependencia sobre los mismos. Una correcta educación para la salud mejorando los hábitos de vida podría prevenir muchos casos de ansiedad